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Homoeriodictyol

$896

  • Brand : BIOFRON

  • Catalogue Number : BD-P0869

  • Specification : 98.0%(HPLC&TLC)

  • CAS number : 446-71-9

  • Formula : C16H14O6

  • Molecular Weight : 302.28

  • PUBCHEM ID : 73635

  • Volume : 25mg

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Catalogue Number

BD-P0869

Analysis Method

HPLC,NMR,MS

Specification

98.0%(HPLC&TLC)

Storage

-20℃

Molecular Weight

302.28

Appearance

Powder

Botanical Source

Structure Type

Flavonoids

Category

Standards;Natural Pytochemical;API

SMILES

COC1=C(C=CC(=C1)C2CC(=O)C3=C(C=C(C=C3O2)O)O)O

Synonyms

5,7,4'-Trihydroxy-3'-methoxyflavanone/4'-methoxy-5,7,3'-trihydroxyflavanone/cyanidanon-3-methyl ether 1625/Eriodictyonone//4',5,7-trihydroxy-3'-methoxyflavanoneEriodictyol 3'-methyl ether/(2S)-5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-2,3-dihydrochromen-4-one

IUPAC Name

(2S)-5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-2,3-dihydrochromen-4-one

Applications

Density

1.458g/cm3

Solubility

Methanol; Acetontrile; DMSO

Flash Point

222.1ºC

Boiling Point

583.8ºC at 760mmHg

Melting Point

225-227ºC (dec.)

InChl

InChI=1S/C16H14O6/c1-21-14-4-8(2-3-10(14)18)13-7-12(20)16-11(19)5-9(17)6-15(16)22-13/h2-6,13,17-19H,7H2,1H3/t13-/m0/s1

InChl Key

FTODBIPDTXRIGS-ZDUSSCGKSA-N

WGK Germany

RID/ADR

HS Code Reference

2932990000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:446-71-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

24711451

Abstract

Knowledge of the regulation of testicular retinoic acid synthesis is crucial for understanding its role in spermatogenesis. Bisdichloroacetyldiamines strongly inhibit spermatogenesis. We reported previously that one of these compounds, WIN 18,446, potently inhibited spermatogenesis in rabbits by inhibiting retinoic acid synthesis. To understand how WIN 18,446 inhibits retinoic acid synthesis, we characterized its effects on human retinal dehydrogenase ALDH1A2 in vitro as well as its effects on retinoid metabolism in vivo using mice. WIN 18,446 strongly and irreversibly inhibited ALDH1A2 in vitro. In vivo, WIN 18,446 treatment completely abolished spermatogenesis after 4 weeks of treatment and modestly reduced adiposity in mice fed a chow diet. Effects of WIN 18,446 on retinoid concentrations were tissue-dependent. Although lung and liver retinyl ester concentrations were lower in WIN 18,446-treated animals, adipose retinyl ester levels were increased following the treatment. Interestingly, animals treated with WIN 18,446 had significantly higher circulating retinol concentrations compared with control mice. The effect on spermatogenesis by WIN 18,446 was not prevented by simultaneous treatment with retinoic acid, whereas effects on other tissues were partially or completely reversed. Cessation of WIN 18,446 treatment for 4 weeks reversed most retinoid-related phenotypes except for inhibition of spermatogenesis. Our data suggest that WIN 18,446 may be a useful model of systemic acquired retinoic acid deficiency. Given the effects observed in our study, inhibition of retinoic acid biosynthesis may have relevance for the treatment of obesity and in the development of novel male contraceptives.

KEYWORDS

Adipose Tissue, Animal Models, Metabolism, Obesity, Vitamin A, ALDH1A2, Bisdichloroacetyldiamine, Fertility, Retinoic Acid

Title

Inhibition of Retinoic Acid Biosynthesis by the Bisdichloroacetyldiamine WIN 18,446 Markedly Suppresses Spermatogenesis and Alters Retinoid Metabolism in Mice*

Author

Jisun Paik,‡,1 Michael Haenisch,‡ Charles H. Muller,§ Alex S. Goldstein,¶ Samuel Arnold,‖ Nina Isoherranen,‖ Thea Brabb,‡ Piper M. Treuting,‡ and John K. Amory*

Publish date

2014 May 23;

PMID

28632728

Abstract

Background:
We previously reported that GTA-446 may be a useful biomarker for early detection of colorectal cancer. In the present study, we confirmed the clinical feasibility of GTA-446 as a screening tool for colorectal cancer with a novel measurement system developed for clinical use. We also improved sensitivity by analysing GTA-446 levels according to gender.

Methods:
Serum samples were collected from 225 colorectal cancer patients and 916 healthy volunteers to measure GTA-446 levels by flow injection analysis-mass spectrometry.

Results:
GTA-446 levels were downregulated in colorectal cancer patients compared with the healthy volunteers, and in females compared with the males in both groups. Receiver operating characteristic curve analysis revealed an optimal cut-off of 2.72 μmol l−1 in males and 1.87 μmol l−1 in females, with a large area under the curve of 0.89-0.93. The sensitivity and specificity were 90.4% and 84.9% for males, 85.2% and 80.5% for females, and 83.3% and 84.8% for all subjects, respectively.

Conclusions:
GTA-446 is a clinically relevant biomarker for colorectal cancer with high sensitivity when analysed by gender. Thus, GTA-446 is a promising tool for primary colorectal cancer screening to identify populations at a higher risk of colorectal cancer, with an emphasis on early detection.

KEYWORDS

GTA-446, metabolite, colorectal cancer, early detection, screening, biomarker

Title

Downregulation of serum metabolite GTA-446 as a novel potential marker for early detection of colorectal cancer

Author

Tsuyoshi Hata,1,3 Ichiro Takemasa,2,3,* Hidekazu Takahashi,1 Naotsugu Haraguchi,1 Junichi Nishimura,1 Taishi Hata,1 Tsunekazu Mizushima,1 Yuichiro Doki,1 and Masaki Mori1

Publish date

2017 Jul 11

PMID

27534393

Title

25th Annual Computational Neuroscience Meeting: CNS-2016

Author

Tatyana O. Sharpee,corresponding author1 Alain Destexhe,corresponding author2,3 Mitsuo Kawato,corresponding author4 Vladislav Sekulić,corresponding author5,6 Frances K. Skinner,5,6,7,179,180,182 Daniel K. Wojcik,corresponding author8 Chaitanya Chintaluri,8 Dorottya Cserpan,9 Zoltan Somogyvari,9 Jae Kyoung Kim,corresponding author10 Zachary P. Kilpatrick,11 Matthew R. Bennett,12 Kresimir Josić,11,13 Irene Elices,corresponding author14 David Arroyo,14 Rafael Levi,14,15 Francisco B. Rodriguez,14 Pablo Varona,corresponding author14 Eunjin Hwang,16,414,418 Bowon Kim,16,17,415 Hio-Been Han,16,18 Tae Kim,19 James T. McKenna,20 Ritchie E. Brown,20 Robert W. McCarley,20 Jee Hyun Choi,corresponding author16,17,412,414,416,417,420 James Rankin,corresponding author21,421 Pamela Osborn Popp,21 John Rinzel,21,22 Alejandro Tabas,corresponding author23 Andre Rupp,24,25 Emili Balaguer-Ballester,23,26 Matias I. Maturana,27,28 David B. Grayden,28,29,249,335,423,424 Shaun L. Cloherty,30 Tatiana Kameneva,corresponding author28 Michael R. Ibbotson,27,31 Hamish Meffin,corresponding author27,31,252,253,334 Veronika Koren,corresponding author32,33 Timm Lochmann,32,33 Valentin Dragoi,34 Klaus Obermayer,32,33 Maria Psarrou,corresponding author35 Maria Schilstra,35 Neil Davey,35 Benjamin Torben-Nielsen,35 Volker Steuber,35 Huiwen Ju,36 Jiao Yu,37 Michael L. Hines,38 Liang Chen,39 Yuguo Yu,corresponding author36 Jimin Kim,40 Will Leahy,41 Eli Shlizerman,corresponding author40,42 Justas Birgiolas,corresponding author43 Richard C. Gerkin,43 Sharon M. Crook,2,44 Atthaphon Viriyopase,corresponding author45,46,47 Raoul-Martin Memmesheimer,45,47,48 Stan Gielen,45,46 Yuri Dabaghian,corresponding author49,50 Justin DeVito,49 Luca Perotti,51 Anmo J. Kim,corresponding author52 Lisa M. Fenk,52 Cheng Cheng,51 Gaby Maimon,52 Chang Zhao,corresponding author53 Yves Widmer,54 Simon Sprecher,54 Walter Senn,43 Geir Halnes,corresponding author55 Tuomo Maki-Marttunen,corresponding author56,361 Daniel Keller,57 Klas H. Pettersen,58,59 Ole A. Andreassen,56,361 Gaute T. Einevoll,55,60,365 Yasunori Yamada,corresponding author61 Moira L. Steyn-Ross,corresponding author62 D. Alistair Steyn-Ross,62 Jorge F. Mejias,corresponding author21 John D. Murray,63 Henry Kennedy,64 Xiao-Jing Wang,21,65 Alexandra Kruscha,corresponding author66,67 Jan Grewe,68,69 Jan Benda,68,69 Benjamin Lindner,66,67,169 Laurent Badel,corresponding author70 Kazumi Ohta,70 Yoshiko Tsuchimoto,70 Hokto Kazama,70 B. Kahng,corresponding author71 Nicoladie D. Tam,corresponding author72 Luca Pollonini,73 George Zouridakis,74 Jaehyun Soh,75 DaeEun Kim,corresponding author75 Minsu Yoo,corresponding author76 S. E. Palmer,77 Viviana Culmone,corresponding author78 Ingo Bojak,78 Andrea Ferrario,corresponding author79 Robert Merrison-Hort,79 Roman Borisyuk,79 Chang Sub Kim,corresponding author80 Taro Tezuka,corresponding author81 Pangyu Joo,corresponding author82 Young-Ah Rho,corresponding author83,84 Shawn D. Burton,85,86 G. Bard Ermentrout,83,86 Jaeseung Jeong,corresponding author84,163,164,190,313,314,316 Nathaniel N. Urban,85,86 Petr Marsalek,corresponding author87,88 Hoon-Hee Kim,84 Seok-hyun Moon,89 Do-won Lee,89 Sung-beom Lee,89 Ji-yong Lee,89 Yaroslav I. Molkov,corresponding author90 Khaldoun Hamade,91 Wondimu Teka,92 William H. Barnett,90 Taegyo Kim,91 Sergey Markin,91 Ilya A. Rybak,91 Csaba Forro,corresponding author93 Harald Dermutz,93 Laszlo Demko,93 Janos Voros,93 Andrey Babichev,49,50 Haiping Huang,corresponding author94 Sergio Verduzco-Flores,corresponding author95 Filipa Dos Santos,corresponding author96 Peter Andras,96 Christoph Metzner,corresponding author97,364 Achim Schweikard,98 Bartosz Zurowski,99 James P. Roach,corresponding author100 Leonard M. Sander,101,102 Michal R. Zochowski,101,102 Quinton M. Skilling,103 Nicolette Ognjanovski,104 Sara J. Aton,104 Michal Zochowski,corresponding author103,105 Sheng-Jun Wang,106,107 Guang Ouyang,107 Jing Guang,108 Mingsha Zhang,108 K. Y. Michael Wong,109 Changsong Zhou,corresponding author107,110,111 Peter A. Robinson,12,112,113,206 Paula Sanz-Leon,corresponding author112,113,206 Peter M. Drysdale,112,113 Felix Fung,112,113 Romesh G. Abeysuriya,112 Chris J. Rennie,112,113 Xuelong Zhao,112,113 Yoonsuck Choe,corresponding author114 Huei-Fang Yang,115 Yuanyuan Mi,116,188 Xiaohan Lin,116 Si Wu,corresponding author116,188 Joscha Liedtke,corresponding author117,118 Manuel Schottdorf,corresponding author117,118 Fred Wolf,117,118 Yoriko Yamamura,corresponding author119 Jeffery R. Wickens,119 Timothy Rumbell,120 Julia Ramsey,121 Amy Reyes,121 Danel Draguljić,121 Patrick R. Hof,122 Jennifer Luebke,123 Christina M. Weaver,corresponding author111 Hu He,124 Xu Yang,corresponding author125 Hailin Ma,124 Zhiheng Xu,124 Yuzhe Wang,124 Kwangyeol Baek,corresponding author126,127 Laurel S. Morris,126 Prantik Kundu,128 Valerie Voon,126 Everton J. Agnes,corresponding author129 Tim P. Vogels,129 William F. Podlaski,corresponding author130 Martin Giese,corresponding author131,344 Pradeep Kuravi,132 Rufin Vogels,131 Alexander Seeholzer,corresponding author133 William Podlaski,134 Rajnish Ranjan,135 Tim Vogels,133 Joaquin J. Torres,136 Fabiano Baroni,137 Roberto Latorre,14 Bart Gips,corresponding author45 Eric Lowet,45,138 Mark J. Roberts,45,138 Peter de Weerd,138 Ole Jensen,45 Jan van der Eerden,45 Abdorreza Goodarzinick,corresponding author139 Mohammad D. Niry,139,140 Alireza Valizadeh,139,141,142,143 Aref Pariz,corresponding author142 Shervin S. Parsi,142 Julia M. Warburton,corresponding author144 Lucia Marucci,145 Francesco Tamagnini,146,147 Jon Brown,148,149 Krasimira Tsaneva-Atanasova,150 Florence I. Kleberg,corresponding author151 Jochen Triesch,151,154 Bahar Moezzi,corresponding author152 Nicolangelo Iannella,152,153 Natalie Schaworonkow,154 Lukas Plogmacher,154 Mitchell R. Goldsworthy,155 Brenton Hordacre,155 Mark D. McDonnell,corresponding author152,336 Michael C. Ridding,155 Martin Zapotocky,corresponding author156,157 Daniel Smit,156,157,158 Coralie Fouquet,158 Alain Trembleau,158 Sakyasingha Dasgupta,corresponding author159,200,401,402 Isao Nishikawa,161 Kazuyuki Aihara,161,440 Taro Toyoizumi,160 Daniel T. Robb,corresponding author162 Nick Mellen,163 Natalia Toporikova,164 Rongxiang Tang,165 Yi-Yuan Tang,corresponding author166 Guangsheng Liang,166 Seth A. Kiser,167 James H. Howard, Jr.,168 Julia Goncharenko,corresponding author35 Sergej O. Voronenko,corresponding author66,169 Tosif Ahamed,corresponding author170 Greg Stephens,170,171 Pierre Yger,corresponding author172 Baptiste Lefebvre,172 Giulia Lia Beatrice Spampinato,172 Elric Esposito,172 Marcel Stimberg et Olivier Marre,172 Hansol Choi,173 Min-Ho Song,corresponding author174 SueYeon Chung,corresponding author175 Dan D. Lee,176 Haim Sompolinsky,175,177 Ryan S. Phillips,corresponding author178,179 Jeffrey Smith,178 Alexandra Pierri Chatzikalymniou,corresponding author179,180 Katie Ferguson,179,181 N. Alex Cayco Gajic,corresponding author183 Claudia Clopath,184,410 R. Angus Silver,183 Padraig Gleeson,corresponding author183,271 Boris Marin,183 Sadra Sadeh,183 Adrian Quintana,183,271 Matteo Cantarelli,185 Salvador Dura-Bernal,186,260,267 William W. Lytton,186,260,266,267 Andrew Davison,187 Luozheng Li,188 Wenhao Zhang,188 Dahui Wang,188,189 Youngjo Song,190 Sol Park,190,191 Ilhwan Choi,191 Hee-sup Shin,191 Hannah Choi,corresponding author40,192,193 Anitha Pasupathy,192,193 Eric Shea-Brown,40,193,425,427 Dongsung Huh,corresponding author194 Terrence J. Sejnowski,194,195 Simon M. Vogt,corresponding author196 Arvind Kumar,197,198,287,291,298,302 Robert Schmidt,196,197 Stephen Van Wert,corresponding author199 Steven J. Schiff,199,200 Richard Veale,corresponding author201 Matthias Scheutz,202 Sang Wan Lee,corresponding author84,203,204 Júlia Gallinaro,corresponding author205 Stefan Rotter,205 Leonid L. Rubchinsky,corresponding author207,208 Chung Ching Cheung,207 Shivakeshavan Ratnadurai-Giridharan,207 Safura Rashid Shomali,corresponding author209 Majid Nili Ahmadabadi,209,210 Hideaki Shimazaki,211 S. Nader Rasuli,212,213 Xiaochen Zhao,116 Malte J. Rasch,corresponding author116 Jens Wilting,corresponding author214 Viola Priesemann,118,214,215,217,218,224 Anna Levina,corresponding author216 Lucas Rudelt,corresponding author218 Joseph T. Lizier,219,220 Richard E. Spinney,220 Mikail Rubinov,221,222 Michael Wibral,223 Ji Hyun Bak,corresponding author225 Jonathan Pillow,226 Yuan Zaho,228,229 Il Memming Park,corresponding author223,227 Jiyoung Kang,230 Hae-Jeong Park,corresponding author231 Jaeson Jang,corresponding author84 Se-Bum Paik,84,225,232,233 Woochul Choi,corresponding author84,232,233 Changju Lee,corresponding author84 Min Song,corresponding author84,233 Hyeonsu Lee,corresponding author84 Youngjin Park,corresponding author84 Ergin Yilmaz,corresponding author234 Veli Baysal,234 Mahmut Ozer,235 Daniel Saska,corresponding author236 Thomas Nowotny,236,237 Ho Ka Chan,corresponding author237 Alan Diamond,237 Christoph S. Herrmann,238 Micah M. Murray,239 Silvio Ionta,239 Axel Hutt,240 Jeremie Lefebvre,corresponding author241 Philipp Weidel,corresponding author242 Renato Duarte,242,243,244 Abigail Morrison,242,243,245,246,292,298,301 Jung H. Lee,corresponding author247,433 Ramakrishnan Iyer,247,433 Stefan Mihalas,247,433 Christof Koch,247 Mihai A. Petrovici,corresponding author248 Luziwei Leng,248 Oliver Breitwieser,247 David Stockel,248 Ilja Bytschok,248 Roman Martel,248 Johannes Bill,248 Johannes Schemmel,248 Karlheinz Meier,248 Timothy B. Esler,corresponding author249 Anthony N. Burkitt,21,28,249 Robert R. Kerr,250 Bahman Tahayori,251 Max Nolte,corresponding author254 Michael W. Reimann,254 Eilif Muller,254 Henry Markram,254 Antonio Parziale,corresponding author255,256 Rosa Senatore,255,256,257 Angelo Marcelli,255,256 K. Skiker,corresponding author258 M. Maouene,259 Samuel A. Neymotin,corresponding author260,261 Alexandra Seidenstein,260,262 Peter Lakatos,263 Terence D. Sanger,264,265 Rosemary J. Menzies,268 Campbell McLauchlan,268 Sacha J. van Albada,269,292 David J. Kedziora,268 Samuel Neymotin,267 Cliff C. Kerr,corresponding author268 Benjamin A. Suter,270 Gordon M. G. Shepherd,270 Juhyoung Ryu,corresponding author272 Sang-Hun Lee,272,273,274,275 Joonwon Lee,corresponding author273 Hyang Jung Lee,corresponding author274 Daeseob Lim,corresponding author275 Jisung Wang,276 Heonsoo Lee,corresponding author276 Nam Jung,277 Le Anh Quang,277 Seung Eun Maeng,277 Tae Ho Lee,277 Jae Woo Lee,corresponding author277 Chang-hyun Park,corresponding author278,279 Sora Ahn,280,282 Jangsup Moon,278,279 Yun Seo Choi,279 Juhee Kim,280 Sang Beom Jun,corresponding author280,281,282 Seungjun Lee,corresponding author280,282 Hyang Woon Lee,278,279,283 Sumin Jo,282 Eunji Jun,282 Suin Yu,282 Felix Goetze,corresponding author284,285 Pik-Yin Lai,284 Seonghyun Kim,286 Jeehyun Kwag,corresponding author286 Hyun Jae Jang,286 Marko Filipović,corresponding author287,288 Ramon Reig,289 Ad Aertsen,287,288 Gilad Silberberg,290 Claudia Bachmann,corresponding author292 Simone Buttler,292 Heidi Jacobs,293,294,295 Kim Dillen,296 Gereon R. Fink,296,297 Juraj Kukolja,296,297 Daniel Kepple,corresponding author299 Hamza Giaffar,299 Dima Rinberg,300 Steven Shea,299 Alex Koulakov,299 Jyotika Bahuguna,corresponding author298,301,302 Tom Tetzlaff,301 Jeanette Hellgren Kotaleski,302 Tim Kunze,corresponding author303,304 Andre Peterson,305 Thomas Knosche,303 Minjung Kim,306 Hojeong Kim,corresponding author306 Ji Sung Park,307 Ji Won Yeon,307 Sung-Phil Kim,corresponding author307,308 Jae-Hwan Kang,308 Chungho Lee,308 Andreas Spiegler,corresponding author309 Spase Petkoski,309,310 Matias J. Palva,311 Viktor K. Jirsa,309 Maria L. Saggio,corresponding author309 Silvan F. Siep,309 William C. Stacey,312,351,352 Christophe Bernar,309 Oh-hyeon Choung,corresponding author84 Yong Jeong,84 Yong-il Lee,84,313 Su Hyun Kim,84,313 Mir Jeong,84 Jeungmin Lee,84,314 Jaehyung Kwon,84,313 Jerald D. Kralik,corresponding author84,314 Jaehwan Jahng,corresponding author84,313 Dong-Uk Hwang,315 Jae-Hyung Kwon,corresponding author84,316 Sang-Min Park,84,316 Seongkyun Kim,84 Hyoungkyu Kim,84 Pyeong Soo Kim,84 Sangsup Yoon,84,313 Sewoong Lim,84,313 Choongseok Park,corresponding author317 Thomas Miller,317 Katie Clements,317 Sungwoo Ahn,318 Eoon Hye Ji,319 Fadi A. Issa,corresponding author317 JeongHun Baek,corresponding author320 Shigeyuki Oba,320 Junichiro Yoshimoto,321,322 Kenji Doya,321 Shin Ishii,320 Thiago S. Mosqueiro,323 Martin F. Strube-Bloss,324 Brian Smith,corresponding author325 Ramon Huerta,323 Michal Hadrava,corresponding author325,326,327 Jaroslav Hlinka,326 Hannah Bos,corresponding author292 Moritz Helias,292,328 Charles M. Welzig,corresponding author329 Zachary J. Harper,329,330 Won Sup Kim,331 In-Seob Shin,331 Hyeon-Man Baek,332 Seung Kee Han,corresponding author331 Rene Richter,corresponding author331 Julien Vitay,331 Frederick Beuth,331 Fred H. Hamker,331,332 Kelly Toppin,333 Yixin Guo,corresponding author333 Bruce P. Graham,337 Penelope J. Kale,corresponding author338 Leonardo L. Gollo,corresponding author338,409,431 Merav Stern,corresponding author339 L. F. Abbott,340 Leonid A. Fedorov,corresponding author341,342 Martin A. Giese,341,342 Mohammad Hovaidi Ardestani,corresponding author343,344 Mohammad Javad Faraji,corresponding author345 Kerstin Preuschoff,346 Wulfram Gerstner,345 Margriet J. van Gendt,corresponding author347 Jeroen J. Briaire,347 Randy K. Kalkman,347 Johan H. M. Frijns,347,348 Won Hee Lee,corresponding author349 Sophia Frangou,349 Ben D. Fulcher,corresponding author350 Patricia H. P. Tran,350 Alex Fornito,350 Stephen V. Gliske,351 Eugene Lim,353 Katherine A. Holman,354 Christian G. Fink,corresponding author353,355 Jinseop S. Kim,corresponding author356,357 Shang Mu,358 Kevin L. Briggman,359 H. Sebastian Seung,356,358 the EyeWirers, Detlef Wegener,corresponding author360 Lisa Bohnenkamp,353,361 Udo A. Ernst,360 Anna Devor,363,364 Anders M. Dale,362,363,368 Glenn T. Lines,367 Andy Edwards,366 Aslak Tveito,366 Espen Hagen,corresponding author292 Johanna Senk,292 Markus Diesmann,292,369,370,376,377,378 Maximilian Schmidt,corresponding author371 Rembrandt Bakker,45,370 Kelly Shen,372 Gleb Bezgin,373 Claus-Christian Hilgetag,374,375 Sacha Jennifer van Albada,370 Haoqi Sun,corresponding author379,380,381,382 Olga Sourina,379,381 Guang-Bin Huang,379,381 Felix Klanner,381,383 Cornelia Denk,381 Katharina Glomb,corresponding author384 Adrian Ponce-Alvarez,383 Matthieu Gilson,corresponding author383,390 Petra Ritter,385,386,387,388 Gustavo Deco,383,389,390 Maria A. G. Witek,391 Eric F. Clarke,392 Mads Hansen,393 Mikkel Wallentin,394 Morten L. Kringelbach,391,394,395 Peter Vuust,391,394 Guido Klingbeil,corresponding author396 Erik De Schutter,396,397,398,399,400 Weiliang Chen,corresponding author397 Yunliang Zang,corresponding author398 Sungho Hong,corresponding author403 Akira Takashima,399 Criseida Zamora,corresponding author400 Andrew R. Gallimore,400 Dennis Goldschmidt,corresponding author400 Poramate Manoonpong,401 Philippa J. Karoly,corresponding author404,407 Dean R. Freestone,corresponding author404,405 Daniel Soundry,405 Levin Kuhlmann,406 Liam Paninski,405 Mark Cook,404 Jaejin Lee,corresponding author408 Yonatan I. Fishman,409 Yale E. Cohen,408 James A. Roberts,corresponding author410,432 Luca Cocchi,410 Yann Sweeney,corresponding author411 Soohyun Lee,412,413 Woo-Sung Jung,412,414 Youngsoo Kim,416 Younginha Jung,418,419 Yoon-Kyu Song,419 Frederic Chavane,422 Karthik Soman,428 Vignesh Muralidharan,428 V. Srinivasa Chakravarthy,corresponding author428 Sabyasachi Shivkumar,428 Alekhya Mandali,428 B. Pragathi Priyadharsini,428 Hima Mehta,428 Catherine E. Davey,corresponding author424 Braden A. W. Brinkman,corresponding author40,426 Tyler Kekona,40 Fred Rieke,426,427 Michael Buice,26 Maurizio De Pittà,corresponding author429,430,435 Hugues Berry,430,431,436 Nicolas Brunel,430,431 Michael Breakspear,432 Gary Marsat,corresponding author437 Jordan Drew,417 Phillip D. Chapman,417 Kevin C. Daly,417 Samual P. Bradle,417 Sat Byul Seo,corresponding author438 Jianzhong Su,434 Ege T. Kavalali,439 Justin Blackwell,434 LieJune Shiau,corresponding author440 Laure Buhry,441 Kanishka Basnayake,442 Sue-Hyun Lee,corresponding author84,443 Brandon A. Levy,444 Chris I. Baker,444,446 Timothee Leleu,corresponding author445 Ryan T. Philips,427 and Karishma Chhabria427

Publish date

2016;