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(-)-Isobicyclogermacrenal

$784

  • Brand : BIOFRON

  • Catalogue Number : BD-P0400

  • Specification : 98.0%(HPLC)

  • CAS number : 73256-82-3

  • Formula : C15H22O

  • Molecular Weight : 218.33458

  • PUBCHEM ID : 13818874

  • Volume : 0.05ml

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Catalogue Number

BD-P0400

Analysis Method

HPLC,NMR,MS

Specification

98.0%(HPLC)

Storage

-20℃

Molecular Weight

218.33458

Appearance

Powder

Botanical Source

Structure Type

Sesquiterpenoids

Category

SMILES

CC1=CCCC(=CC2C(C2(C)C)CC1)C=O

Synonyms

(1R,2E,6Z,10S)-7,11,11-trimethylbicyclo[8.1.0]undeca-2,6-diene-3-carbaldehyde

IUPAC Name

(1R,2E,6E,10S)-7,11,11-trimethylbicyclo[8.1.0]undeca-2,6-diene-3-carbaldehyde

Applications

Density

Solubility

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

Flash Point

Boiling Point

Melting Point

InChl

InChI=1S/C15H22O/c1-11-5-4-6-12(10-16)9-14-13(8-7-11)15(14,2)3/h5,9-10,13-14H,4,6-8H2,1-3H3/b11-5-,12-9+/t13-,14+/m0/s1

InChl Key

BLCUVJCHWZPQCX-CWAMIXHFSA-N

WGK Germany

RID/ADR

HS Code Reference

2933990000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:73256-82-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

26343630

Abstract

As a classical herb pair in clinics of traditional Chinese medicine, Curcumae Rhizoma-Sparganii Rhizoma (HP CR-SR) is used for activating blood circulation to remove blood stasis. The essential components in HP CR-SR and its single herbs were comparatively analyzed using gas chromatography-mass spectrometry data. 66, 22, and 54 components in volatile oils of Curcumae Rhizoma, Sparganii Rhizoma, and HP CR-SR were identified, and total contents accounted for 75.416%, 91.857%, and 79.553% respectively. The thirty-eight components were found in HP CR-SR, and not detected in single herbs Curcumae Rhizoma and Sparganii Rhizoma. The highest radical trapping action was seen by an essential oil of HP CR-SR (IC50 = 0.59 ± 0.04 mg/mL). Furthermore, the HP CR-SR essential oil showed more remarkable cytotoxicity on tumor cell lines than that of the single herbs Curcumae Rhizoma and Sparganii Rhizoma in a dose-dependent manner: IC50 values showing 32.32 ± 5.31 μg/mL (HeLa), 34.76 ± 1.82 μg/mL (BGC823), 74.84 ± 1.66 μg/mL (MCF-7), 66.12 ± 11.23 μg/mL (SKOV3), and 708.24 ± 943.91 μg/mL (A549), respectively. In summary, the essential oil of HP CR-SR is different from any one of Curcumae Rhizoma and Sparganii Rhizoma, nor simply their superposition, and HP CR-SR oil presented more remarkable anticancer and antioxidant activities compared with Curcumae Rhizoma and Sparganii Rhizoma oils.

KEYWORDS

Curcumae Rhizoma, Sparganii Rhizoma, Curcumae Rhizoma-Sparganii Rhizoma, herb pair, essential oils, antioxidant activity, anti-cancer activity

Title

Chemical Composition, Antioxidative and Anticancer Activities of the Essential Oil: Curcumae Rhizoma-Sparganii Rhizoma, a Traditional Herb Pair

Author

Guan-Ling Xu,1 Di Geng,1 Meng Xie,1 Kai-Yue Teng,1 Yu-Xin Tian,1 Zi-Zhen Liu,1 Cheng Yan,1 Yan Wang,1 Xia Zhang,1 Yan Song,2 Yue Yang,1 and Gai-Mei She1,* Derek J. McPhee, Academic Editor

Publish date

2015 Sep;