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Isocurcumenol

$250

  • Brand : BIOFRON

  • Catalogue Number : BF-I4004

  • Specification : 98%(HPLC)

  • CAS number : 24063-71-6

  • Formula : C15H22O2

  • Molecular Weight : 234.3

  • PUBCHEM ID : 10399139

  • Volume : 25mg

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Catalogue Number

BF-I4004

Analysis Method

HPLC,NMR,MS

Specification

98%(HPLC)

Storage

-20℃

Molecular Weight

234.3

Appearance

Cryst.

Botanical Source

Curcuma wenyujin,Curcuma phaeocaulis

Structure Type

Terpenoids

Category

Standards;Natural Pytochemical;API

SMILES

CC1CCC2C13CC(=C(C)C)C(O3)(CC2=C)O

Synonyms

Isocurcumenol/9-Isopropylidene-2-methyl-6-methylene-11-oxatricyclo[6.2.1.0]undecan-8-ol/isocurcomenol/6H-3a,6-Epoxyazulen-6-ol, octahydro-3-methyl-8-methylene-5-(1-methylethylidene)-/(1S,2S,5S,8R)-9-Isopropylidene-2-methyl-6-methylene-11-oxa-tricyclo[6.2.1.01,5]undecan-8-ol/(3a,3aα,6α,8aβ)-5-isopropylidene-3-methyl-8-methylene-3a,6-epoxyperhydroazulen-6-ol/Isourecumenol

IUPAC Name

(1S,2S,5S,8R)-2-methyl-6-methylidene-9-propan-2-ylidene-11-oxatricyclo[6.2.1.01,5]undecan-8-ol

Applications

Antitumour Effects of?Isocurcumenol?Isolated from Curcuma zedoaria Rhizomes on Human and Murine Cancer Cells. PUMID/DOI:27429805 Int J Med Chem.?2011;2011:253962. Curcuma zedoaria belonging to the family Zingiberaceae has been used in the traditional system of medicine in India and Southwest Asia in treating many human ailments and is found to possess many biological activities. The rationale of the present study was to isolate, identify, and characterize antitumour principles from the rhizomes of Curcuma zedoaria, to assess its cytotoxic effects on human and murine cancer cells, to determine its apoptosis inducing capacity in cancer cells, and to evaluate its tumour reducing properties in in vivo mice models.?Isocurcumenol?was characterized as the active compound by spectroscopy and was found to inhibit the proliferation of cancer cells without inducing significant toxicity to the normal cells. Fluorescent staining exhibited the morphological features of apoptosis in the compound-treated cancer cells. In vivo tumour reduction studies revealed that a dose of 35.7?mg/kg body weight significantly reduced the ascitic tumour in DLA-challenged mice and increased the lifespan with respect to untreated control mice.

Density

1.1±0.1 g/cm3

Solubility

Methanol; Ethyl Acetate

Flash Point

147.9±22.1 °C

Boiling Point

351.0±42.0 °C at 760 mmHg

Melting Point

InChl

InChI=1S/C15H22O2/c1-9(2)13-8-14-11(4)5-6-12(14)10(3)7-15(13,16)17-14/h11-12,16H,3,5-8H2,1-2,4H3/t11-,12-,14-,15+/m0/s1

InChl Key

DEBDFZGNZTYPMF-NZBPQXDJSA-N

WGK Germany

RID/ADR

HS Code Reference

2938900000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:24063-71-6) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

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