Catalogue Number
BF-I4004
Analysis Method
HPLC,NMR,MS
Specification
98%(HPLC)
Storage
-20℃
Molecular Weight
234.3
Appearance
Cryst.
Botanical Source
Curcuma wenyujin,Curcuma phaeocaulis
Structure Type
Terpenoids
Category
Standards;Natural Pytochemical;API
SMILES
CC1CCC2C13CC(=C(C)C)C(O3)(CC2=C)O
Synonyms
Isocurcumenol/9-Isopropylidene-2-methyl-6-methylene-11-oxatricyclo[6.2.1.0]undecan-8-ol/isocurcomenol/6H-3a,6-Epoxyazulen-6-ol, octahydro-3-methyl-8-methylene-5-(1-methylethylidene)-/(1S,2S,5S,8R)-9-Isopropylidene-2-methyl-6-methylene-11-oxa-tricyclo[6.2.1.01,5]undecan-8-ol/(3a,3aα,6α,8aβ)-5-isopropylidene-3-methyl-8-methylene-3a,6-epoxyperhydroazulen-6-ol/Isourecumenol
IUPAC Name
(1S,2S,5S,8R)-2-methyl-6-methylidene-9-propan-2-ylidene-11-oxatricyclo[6.2.1.01,5]undecan-8-ol
Density
1.1±0.1 g/cm3
Solubility
Methanol; Ethyl Acetate
Flash Point
147.9±22.1 °C
Boiling Point
351.0±42.0 °C at 760 mmHg
Melting Point
InChl
InChI=1S/C15H22O2/c1-9(2)13-8-14-11(4)5-6-12(14)10(3)7-15(13,16)17-14/h11-12,16H,3,5-8H2,1-2,4H3/t11-,12-,14-,15+/m0/s1
InChl Key
DEBDFZGNZTYPMF-NZBPQXDJSA-N
WGK Germany
RID/ADR
HS Code Reference
2938900000
Personal Projective Equipment
Correct Usage
For Reference Standard and R&D, Not for Human Use Directly.
Meta Tag
provides coniferyl ferulate(CAS#:24063-71-6) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate
MSDS
No Article Available.
Description :
Antitumour Effects of?Isocurcumenol?Isolated from Curcuma zedoaria Rhizomes on Human and Murine Cancer Cells. PUMID/DOI：27429805 Int J Med Chem.?2011;2011:253962. Curcuma zedoaria belonging to the family Zingiberaceae has been used in the traditional system of medicine in India and Southwest Asia in treating many human ailments and is found to possess many biological activities. The rationale of the present study was to isolate, identify, and characterize antitumour principles from the rhizomes of Curcuma zedoaria, to assess its cytotoxic effects on human and murine cancer cells, to determine its apoptosis inducing capacity in cancer cells, and to evaluate its tumour reducing properties in in vivo mice models.?Isocurcumenol?was characterized as the active compound by spectroscopy and was found to inhibit the proliferation of cancer cells without inducing significant toxicity to the normal cells. Fluorescent staining exhibited the morphological features of apoptosis in the compound-treated cancer cells. In vivo tumour reduction studies revealed that a dose of 35.7?mg/kg body weight significantly reduced the ascitic tumour in DLA-challenged mice and increased the lifespan with respect to untreated control mice.
