Shipping to Germany We Offer Worldwide Shipping
Login Wishlist

Isoforskolin

$905

  • Brand : BIOFRON

  • Catalogue Number : AV-P12392

  • Specification : 98%

  • CAS number : 64657-21-2

  • Formula : C22H34O7

  • Molecular Weight : 410.5

  • PUBCHEM ID : 10001602

  • Volume : 20mg

Available on backorder

Quantity
Checkout Bulk Order?

Catalogue Number

AV-P12392

Analysis Method

HPLC,NMR,MS

Specification

98%

Storage

2-8°C

Molecular Weight

410.5

Appearance

Powder

Botanical Source

Constit. of Coleus forskohlii and Excoecaria cochinchinensis

Structure Type

Diterpenoids

Category

SMILES

CC(=O)OC1C2C(CCC(C2(C3(C(=O)CC(OC3(C1O)C)(C)C=C)O)C)O)(C)C

Synonyms

[(3R,4aR,5S,6S,10S,10aR,10bS)-3-ethenyl-5,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-5,6,6a,8,9,10-hexahydro-2H-benzo[f]chromen-6-yl] acetate

IUPAC Name

[(3R,4aR,5S,6S,10S,10aR,10bS)-3-ethenyl-5,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-5,6,6a,8,9,10-hexahydro-2H-benzo[f]chromen-6-yl] acetate

Applications

Density

1.2±0.1 g/cm3

Solubility

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

Flash Point

173.6±23.6 °C

Boiling Point

524.5±50.0 °C at 760 mmHg

Melting Point

InChl

InChI=1S/C22H34O7/c1-8-19(5)11-14(25)22(27)20(6)13(24)9-10-18(3,4)16(20)15(28-12(2)23)17(26)21(22,7)29-19/h8,13,15-17,24,26-27H,1,9-11H2,2-7H3/t13-,15-,16?,17-,19-,20-,21+,22-/m0/s1

InChl Key

CLOQVZCSBYBUPB-VDCUXWMXSA-N

WGK Germany

RID/ADR

HS Code Reference

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:64657-21-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

23983079

Abstract

Objective
To study the comorbidity of common mental disorders (CMDs) and cancer, and the mental health treatment gap among community residents with active cancer, cancer survivors and cancer-free respondents in 13 high- and 11 low-middle income countries.

Methods
Data were derived from the World Mental Health Surveys (N=66,387; n=357 active cancer, n=1,373 cancer survivors, n=64,657 cancer free respondents). The WHO/Composite International Diagnostic Interview was used in all surveys to estimate CMDs prevalence rates. Respondents were also asked about mental health service utilization in the preceding 12 months. Cancer status was ascertained by self-report of physician’s diagnosis.

Results
Twelve month prevalence rates of CMDs were higher among active cancer (18.4% SE=2.1) than cancer free respondents (13.3%, SE=0.2) adjusted for socio-demographic confounders and other lifetime chronic conditions (Adjusted Odds Ratio (AOR)=1.44 95% CI 1.05-1.97). CMD rates among cancer survivors (14.6% SE=0.9) compared with cancer-free respondents did not differ significantly (AOR=0.95 95% CI 0.82-1.11). Similar patterns characterized high and low-middle income countries. Of respondents with active cancer who had CMD in the preceding 12 months 59% sought services for mental health problems (SE=5.3). The pattern of service utilization among people with CMDs by cancer status (highest among persons with active cancer, lower among survivors and lowest among cancer-free respondents) was similar in high- (64.0% SE=6.0, 41.2% SE=3.0, 35.6% SE=0.6) and low-middle income countries (46.4% SE=11.0, 22.5% SE=9.1, 17.4% SE=0.7).

Conclusions
Community respondents with active cancer have relatively higher CMD rates and relatively high treatment gap. Comprehensive cancer care should consider both factors.

KEYWORDS

Cancer, Epidemiology, Mental health, Oncology, Treatment gap, World Mental Health Surveys

Title

Comorbidity of common mental disorders with cancer and their treatment gap: Findings from the World Mental Health Surveys

Author

Ora Nakash,1 Itzhak Levav,2 Sergio Aguilar-Gaxiola,3 Jordi Alonso,4 Laura Helena Andrade,5 Matthias C. Angermeyer,6 Ronny Bruffaerts,7 Jose Miguel Caldas-de-Almeida,8 Slivia Florescu,9 Giovanni de Girolamo,10 Oye Gureje,11 Yanling He,12 Chiyi Hu,13 Peter de Jonge,14 Elie G. Karam,15 Viviane Kovess-Masfety,16 Maria Elena Medina-Mora,17 Jacek Moskalewicz,18 Sam Murphy,19 Yosikazu Nakamura,20 Marina Piazza,21 Jose Posada-Villa,22 Dan J. Stein,23 Nezar Ismet Taib,24 Zahari Zarkov,25 Ronald C. Kessler,26 and Kate M. Scott27

Publish date

2015 Jan 1.

PMID

31516929

Abstract

Control and manipulation of synthesis parameters of thin film coatings is of critical concern in determination of material properties and performance. Structural and morphological properties of rf-sputtered WC-Co thin films deposited under varying deposition parameters namely, substrate temperature and rf power are presented in this data article. The surface morphology, crystallite size and nature were acquired using x-ray photoelectron spectroscopy (XPS) and Grazing Incidence X-ray absorption spectroscopy (GI-XAS). Furthermore, Synchrotron findings are correlated with complimentary data acquired from Scanning electron microscopy (SEM), Raman spectroscopy and surface profilometry to predict and point out optimum synthesis parameters for best properties of the film.

KEYWORDS

WC-Co thin films, X-ray photoelectron spectroscopy (XPS), Grazing incidence X-ray absorption spectroscopy (GI-XAS), Synchrotron radiation, SEM

Title

Structural and morphological dataset for rf-sputtered WC-Co thin films using synchrotron radiation methods

Author

R.R. Phiri,a O.P. Oladijo,a,b,? H. Nakajima,c A. Rattanachata,c and E.T. Akinlabib

Publish date

2019 Aug;

PMID

29334890

Abstract

Background
Late embryogenesis abundant (LEA) proteins are large groups of hydrophilic proteins with major role in drought and other abiotic stresses tolerance in plants. In-depth study and characterization of LEA protein families have been carried out in other plants, but not in upland cotton. The main aim of this research work was to characterize the late embryogenesis abundant (LEA) protein families and to carry out gene expression analysis to determine their potential role in drought stress tolerance in upland cotton. Increased cotton production in the face of declining precipitation and availability of fresh water for agriculture use is the focus for breeders, cotton being the backbone of textile industries and a cash crop for many countries globally.

Results
In this work, a total of 242, 136 and 142 LEA genes were identified in G. hirsutum, G. arboreum and G. raimondii respectively. The identified genes were classified into eight groups based on their conserved domain and phylogenetic tree analysis. LEA 2 were the most abundant, this could be attributed to their hydrophobic character. Upland cotton LEA genes have fewer introns and are distributed in all chromosomes. Majority of the duplicated LEA genes were segmental. Syntenic analysis showed that greater percentages of LEA genes are conserved. Segmental gene duplication played a key role in the expansion of LEA genes. Sixty three miRNAs were found to target 89 genes, such as miR164, ghr-miR394 among others. Gene ontology analysis revealed that LEA genes are involved in desiccation and defense responses. Almost all the LEA genes in their promoters contained ABRE, MBS, W-Box and TAC-elements, functionally known to be involved in drought stress and other stress responses. Majority of the LEA genes were involved in secretory pathways. Expression profile analysis indicated that most of the LEA genes were highly expressed in drought tolerant cultivars Gossypium tomentosum as opposed to drought susceptible, G. hirsutum. The tolerant genotypes have a greater ability to modulate genes under drought stress than the more susceptible upland cotton cultivars.

Conclusion
The finding provides comprehensive information on LEA genes in upland cotton, G. hirsutum and possible function in plants under drought stress.

Electronic supplementary material
The online version of this article (10.1186/s12863-017-0596-1) contains supplementary material, which is available to authorized users.

KEYWORDS

Cotton (Gossypium spp), Identification, LEA proteins, miRNAs, Gene ontology, Gene expression, Genome, Drought

Title

Characterization of the late embryogenesis abundant (LEA) proteins family and their role in drought stress tolerance in upland cotton

Author

Richard Odongo Magwanga,1,2 Pu Lu,1 Joy Nyangasi Kirungu,1 Hejun Lu,1 Xingxing Wang,1 Xiaoyan Cai,1 Zhongli Zhou,1 Zhenmei Zhang,1 Haron Salih,1 Kunbo Wang,corresponding author1 and Fang Liucorresponding author1

Publish date

2018