We Offer Worldwide Shipping
Login Wishlist

Isoniazid

$43

  • Brand : BIOFRON

  • Catalogue Number : BF-I2007

  • Specification : 98%

  • CAS number : 54-85-3

  • Formula : C6H7N3O

  • Molecular Weight : 137.14

  • PUBCHEM ID : 3767

  • Volume : 20mg

In stock

Quantity
Checkout Bulk Order?

Catalogue Number

BF-I2007

Analysis Method

HPLC,NMR,MS

Specification

98%

Storage

2-8°C

Molecular Weight

137.14

Appearance

Powder

Botanical Source

synthesis

Structure Type

Others

Category

Standards;Natural Pytochemical;API

SMILES

C1=CN=CC=C1C(=O)NN

Synonyms

INH/RIMIFON/Isonicotinyl hydrazide/Isoniazide/4-pyridine-carbonic acid hydrazide/LANIAZID/Pyridine-4-carboxylic hydrazide/In-73/pyridine-4-carbohydrazide/4-pyridinecarbohydrazide/Cedin/pyridine-4-carboxylic acid hydrazide/Hyzyd/Isoniazid/HIA/4-Pyridinecarboxylic acid, hydrazide/isonicotinic acid hydrazid/Isonicotinate hydrazide/INAH/Isonicotinohydrazide/Isonicotinic acid hydrazide/isonicotinoyl hydrazide/fsr3/GINK/NYDRAZID

IUPAC Name

pyridine-4-carbohydrazide

Density

1.2±0.1 g/cm3

Solubility

Flash Point

>250°C

Boiling Point

Melting Point

171-173 °C(lit.)

InChl

InChl Key

WGK Germany

RID/ADR

HS Code Reference

2933390000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:54-85-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

PMID

32212527

Title

Telacebec (Q203), a New Antituberculosis Agent.

Author

de Jager VR1, Dawson R2, van Niekerk C3, Hutchings J3, Kim J3, Vanker N4, van der Merwe L5, Choi J3, Nam K3, Diacon AH6.

Publish date

2020 Mar 26;

PMID

32187483

Title

HIV, Pregnancy, and Isoniazid Preventive Therapy. Reply.

Author

Gupta A, Montepiedra G, Theron G

Publish date

2020 Mar 19

PMID

32187482

Title

HIV, Pregnancy, and Isoniazid Preventive Therapy.

Author

Tiendrebeogo T, Anglaret X, Becquet R.

Publish date

2020 Mar 19


Description :

Isoniazid is an antibacterial agent used primarily as a tuberculostatic.Target: AntibacterialIsoniazid is a prodrug and must be activated by a bacterial catalase-peroxidase enzyme that in M. tuberculosis is called KatG [1]. KatG couples the isonicotinic acyl with NADH to form isonicotinic acyl-NADH complex. This complex binds tightly to the enoyl-acyl carrier protein reductase known as InhA, thereby blocking the natural enoyl-AcpM substrate and the action of fatty acid synthase. This process inhibits the synthesis of mycolic acid, required for the mycobacterial cell wall. A range of radicals are produced by KatG activation of isoniazid, including nitric oxide, which has also been shown to be important in the action of another antimycobacterial prodrug PA-824 [2, 3]. Isoniazid is bactericidal to rapidly dividing mycobacteria, but is bacteriostatic if the mycobacteria are slow-growing [4].