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Kaempferol

$65

  • Brand : BIOFRON

  • Catalogue Number : BD-D1339

  • Specification : 98%(HPLC)

  • CAS number : 520-18-3

  • Formula : C15H10O6

  • Molecular Weight : 286.24

  • PUBCHEM ID : 5280863

  • Volume : 20MG

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Catalogue Number

BD-D1339

Analysis Method

HPLC,NMR,MS

Specification

98%(HPLC)

Storage

-20℃

Molecular Weight

286.24

Appearance

Yellow crystalline powder

Botanical Source

Kaempferia galanga L./Very widespread in the plant world, e.g. in Cruciferae, Apocynaceae, Dilleniaceae, Ranunculaceae, Leguminosae, etc.

Structure Type

Flavonols/Flavanonols

Category

Standards;Natural Pytochemical;API

SMILES

C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O

Synonyms

3,4',5,7-Tetrahydroxyflavone Hydrate/4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2- (4-hydroxyphenyl)-/Pelargidenolon/4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-/campherol/3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one/KaeMpferol Hydrate/Swartziol/asurone/3,5,7,4'-tetrahydroxyflavone/nimbecetin/Trifolitin/Populnetin/3 4' 5 7-tetrahydroxyflavone/5,7,4'-trihydroxyflavonol/kampherol/Kaempferol/Rhamnolutin/Robigenin/Swartsiol/Rhamnolutein/3,4',5,7-tetrahydroxyflavone/3,4,5,7-Tetrahydroxyflavone/kempferol

IUPAC Name

3,5,7-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one

Density

1.7±0.1 g/cm3

Solubility

Methanol

Flash Point

226.1±23.6 °C

Boiling Point

582.1±50.0 °C at 760 mmHg

Melting Point

276°C

InChl

InChl Key

WGK Germany

RID/ADR

HS Code Reference

2932990000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:520-18-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

25982933

Abstract

Inflammation is an important process of human healing response, wherein the tissues respond to injuries induced by many agents including pathogens. It is characterized by pain, redness and heat in the injured tissues. Chronic inflammation seems to be associated with different types of diseases such as arthritis, allergies, atherosclerosis, and even cancer. In recent years natural product based drugs are considered as the novel therapeutic strategy for prevention and treatment of inflammatory diseases. Among the different types of phyto-constituents present in natural products, flavonoids which occur in many vegetable foods and herbal medicines are considered as the most active constituent, which has the potency to ameliorate inflammation under both in vitro and in vivo conditions. Kaempferol is a natural flavonol present in different plant species, which has been described to possess potent anti-inflammatory properties. Despite the voluminous literature on the anti-inflammatory effects of kaempferol, only very limited review articles has been published on this topic. Hence the present review is aimed to provide a critical overview on the anti-inflammatory effects and the mechanisms of action of kaempferol, based on the current scientific literature. In addition, emphasis is also given on the chemistry, natural sources, bioavailability and toxicity of kaempferol.

Copyright © 2015 Elsevier Ltd. All rights reserved.

KEYWORDS

Anti-inflammatory activity; Flavonoids; Kaempferol; Pro-inflammatory cytokines

Title

Kaempferol and inflammation: From chemistry to medicine.

Author

Devi KP1, Malar DS1, Nabavi SF2, Sureda A3, Xiao J4, Nabavi SM5, Daglia M6.

Publish date

2015 Sep


Description :

Kaempferol inhibits estrogen receptor α expression in breast cancer cells and induces apoptosis in glioblastoma cells and lung cancer cells by activation of MEK-MAPK.