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Catalogue Number
BD-D1339
Analysis Method
HPLC,NMR,MS
Specification
98%(HPLC)
Storage
-20℃
Molecular Weight
286.24
Appearance
Yellow crystalline powder
Botanical Source
Kaempferia galanga L./Very widespread in the plant world, e.g. in Cruciferae, Apocynaceae, Dilleniaceae, Ranunculaceae, Leguminosae, etc.
Structure Type
Flavonols/Flavanonols
Category
Standards;Natural Pytochemical;API
SMILES
C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O
Synonyms
3,4',5,7-Tetrahydroxyflavone Hydrate/4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2- (4-hydroxyphenyl)-/Pelargidenolon/4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-/campherol/3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one/KaeMpferol Hydrate/Swartziol/asurone/3,5,7,4'-tetrahydroxyflavone/nimbecetin/Trifolitin/Populnetin/3 4' 5 7-tetrahydroxyflavone/5,7,4'-trihydroxyflavonol/kampherol/Kaempferol/Rhamnolutin/Robigenin/Swartsiol/Rhamnolutein/3,4',5,7-tetrahydroxyflavone/3,4,5,7-Tetrahydroxyflavone/kempferol
IUPAC Name
3,5,7-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one
Applications
Kaempferol inhibits estrogen receptor α expression in breast cancer cells and induces apoptosis in glioblastoma cells and lung cancer cells by activation of MEK-MAPK.
Density
1.7±0.1 g/cm3
Solubility
Methanol
Flash Point
226.1±23.6 °C
Boiling Point
582.1±50.0 °C at 760 mmHg
Melting Point
276°C
InChl
InChl Key
WGK Germany
RID/ADR
HS Code Reference
2932990000
Personal Projective Equipment
Correct Usage
For Reference Standard and R&D, Not for Human Use Directly.
Meta Tag
provides coniferyl ferulate(CAS#:520-18-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate
No Technical Documents Available For This Product.
25982933
Inflammation is an important process of human healing response, wherein the tissues respond to injuries induced by many agents including pathogens. It is characterized by pain, redness and heat in the injured tissues. Chronic inflammation seems to be associated with different types of diseases such as arthritis, allergies, atherosclerosis, and even cancer. In recent years natural product based drugs are considered as the novel therapeutic strategy for prevention and treatment of inflammatory diseases. Among the different types of phyto-constituents present in natural products, flavonoids which occur in many vegetable foods and herbal medicines are considered as the most active constituent, which has the potency to ameliorate inflammation under both in vitro and in vivo conditions. Kaempferol is a natural flavonol present in different plant species, which has been described to possess potent anti-inflammatory properties. Despite the voluminous literature on the anti-inflammatory effects of kaempferol, only very limited review articles has been published on this topic. Hence the present review is aimed to provide a critical overview on the anti-inflammatory effects and the mechanisms of action of kaempferol, based on the current scientific literature. In addition, emphasis is also given on the chemistry, natural sources, bioavailability and toxicity of kaempferol.
Copyright © 2015 Elsevier Ltd. All rights reserved.
Anti-inflammatory activity; Flavonoids; Kaempferol; Pro-inflammatory cytokines
Kaempferol and inflammation: From chemistry to medicine.
Devi KP1, Malar DS1, Nabavi SF2, Sureda A3, Xiao J4, Nabavi SM5, Daglia M6.
2015 Sep
