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L-Hyoscyamine

$113

  • Brand : BIOFRON

  • Catalogue Number : BF-L2003

  • Specification : 98%

  • CAS number : 101-31-5

  • Formula : C17H23NO3

  • Molecular Weight : 289.37

  • PUBCHEM ID : 154417

  • Volume : 20mg

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Catalogue Number

BF-L2003

Analysis Method

HPLC,NMR,MS

Specification

98%

Storage

2-8°C

Molecular Weight

289.37

Appearance

White crystal

Botanical Source

roots of Anisodus tanguticus

Structure Type

Alkaloids

Category

Standards;Natural Pytochemical;API

SMILES

CN1[C@@H]2CC[C@H]1CC(C2)OC(=O)[C@H](CO)C3=CC=CC=C3

Synonyms

CYSTOSPAZ/L-Hyoscyamine/3a-Tropanyl S-(-)-Tropate/(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl-(2S)-3-hydroxy-2-phenylpropanoat/scopolamine HCl/SCOPINE TROPATE/Levsin/(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl (2S)-3-hydroxy-2-phenylpropanoate/(S)-(-)-hyoscyamine/Benzeneacetic acid, α-(hydroxymethyl)-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, (αS)-/SCOPINE TROPATE HYDROCHLORIDE/Benzeneacetic acid, α-(hydroxymethyl)-, (3-endo)-8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, (αS)-/(S)-atropine/Hyoscyamine/(-)-Hycosamine/(-)-Hyoscyamine/Daturine/chlorhydratedescopolamine/Egacene/1-Tropic Acid Ester with Tropine/(-)-atropine/er),hcl/[3(S)-endo]-a-(Hydroxymethyl)benzeneacetic Acid 8-Methyl-8-azabicyclo[3.2.1]oct-3-yl Ester/Peptard/ScopolamineSeries/L-Tropine tropate/(2S)-(1R,5S)-8-Methyl-8-azabicyclo[3.2.1]octan-3-yl 3-hydroxy-2-phenylpropanoate/1aH,5aH-Tropan-3a-ol(-)-tropate (Ester)

IUPAC Name

[(1S,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] (2S)-3-hydroxy-2-phenylpropanoate

Density

1.2±0.1 g/cm3

Solubility

Ethanol; Chloroform

Flash Point

213.7±28.7 °C

Boiling Point

429.8±45.0 °C at 760 mmHg

Melting Point

108.5ºC

InChl

InChI=1S/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13-,14+,15?,16-/m1/s1

InChl Key

RKUNBYITZUJHSG-VFSICIBPSA-N

WGK Germany

RID/ADR

HS Code Reference

2939800000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:101-31-5) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

PMID

31108527

Title

Hyoscyamine for a Slow Ventricular Response During Atrial Fibrillation.

Author

Helgeson SA1, Mwakyanjala EJ1, Parikh PP1, Venkatachalam KL1.

Publish date

2019 May 21

PMID

31108526

Title

Hyoscyamine for a Slow Ventricular Response During Atrial Fibrillation.

Author

Gupta N1.

Publish date

2019 May 21

PMID

30560886

Abstract

Plant secondary metabolites play a major role in plant adaptation to stress. Species belonging to Solanaceae family and Datura genus produce tropane alkaloids: D. stramonium, D. tatula and D. innoxia. These species are cultivated for their hyoscyamine (HS) content, whence the interest of this study to induce transformed roots of these species with strain A4 of Agrobacterium rhizogenes. Hairy roots (HRs) of Datura were established at high frequency by infecting vitroplants. All HRs (343 independent lines) were next employed to study the production of HS and growth. A screening of HRs alkaloid content by GC/MS is performed; it reveals, for the first time, the production of 13 alkaloids by the selected root lines. The selection of high productive line offers an interesting option to enhance the productivity. As HS is the dominant compound, the lines of Datura species were selected for their characteristics for biomass and HS production. The elicitors salicylic acid (SA) and acetyl salicylic acid (ASA) were also used to increase HS production. The results showed that the optimal concentration of the two elicitors (AS and ASA) was 0.1 mM. The highest HS content (17.94 ± 0.14 mg g-1 D.W.) obtained in HRs of D. tatula treated with 0.1 mM of acetyl salicylic acid.

Title

Tropane alkaloids GC/MS analysis and low dose elicitors' effects on hyoscyamine biosynthetic pathway in hairy roots of Algerian Datura species.

Author

Harfi B1,2, Khelifi L3, Khelifi-Slaoui M3, Assaf-Ducrocq C4, Gontier E4.

Publish date

2018 Dec 18


Description :

L-Hyoscyamine is a chemical compound, a tropane alkaloid it is the levo-isomer to atropine.Target: mAChRHyoscyamine is a chemical compound, a tropane alkaloid it is the levo-isomer to atropine. It is a secondary metabolite of some plants, particularly henbane (Hyoscamus niger.)Hyoscyamine is used to provide symptomatic relief to various gastrointestinal disorders including spasms, peptic ulcers, irritable bowel syndrome, pancreatitis, colic and cystitis. It has also been used to relieve some heart problems, control some of the symptoms of Parkinson's disease, as well as for control of respiratory secretions in end of life care [1].