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L-Leucine

$43

  • Brand : BIOFRON

  • Catalogue Number : BF-L3013

  • Specification : 98%

  • CAS number : 61-90-5

  • Formula : C6H13NO2

  • Molecular Weight : 131.17

  • PUBCHEM ID : 6106

  • Volume : 100mg

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Catalogue Number

BF-L3013

Analysis Method

HPLC,NMR,MS

Specification

98%

Storage

2-8°C

Molecular Weight

131.17

Appearance

White needle crystal

Botanical Source

cultures of Corynebacterium glutamicum.

Structure Type

Others

Category

Standards;Natural Pytochemical;API

SMILES

CC(C)CC(C(=O)O)N

Synonyms

Glusate/H-L-GLU-OH/Leucine/L-GLU/(l)-leucine/H-GLU-OH/[14C]-L-(+)-Leucine/GLU/[14C]-L-Glutamic acid/L-2-Amino-4-methylpentanoic acid/(2S)-α-Leucine/GLUTACID/4-Methyl-L-norvaline/LEUCINE, L-/l-Leu/Leucinum/[3H]-L-Glutamic acid/Leucine (USP)/L-Leucine/S-leucine/QVYZ1Y1&1 &&L or S Form/2-Amino-4-methylpentanoic acid, (S)-/H-Leu-OH/(S)-2-amino-4-methyl-pentanoic acid/L-(+)-glutamic acid/(S)-(+)-Leucine/Aciglut/(S)-leucine/glutamic/L-(-)-2-Amino-4-methylpentanoic acid/LEU/Glutaton

IUPAC Name

(2S)-2-amino-4-methylpentanoic acid

Density

1.0±0.1 g/cm3

Solubility

Aqueous acid

Flash Point

90.3±22.6 °C

Boiling Point

225.8±23.0 °C at 760 mmHg

Melting Point

286-288 ºC

InChl

InChl Key

WGK Germany

RID/ADR

HS Code Reference

2922490000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:61-90-5) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

PMID

31055970

Abstract

l-Leucine, as an essential branched-chain amino acid for humans and animals, has recently been attracting much attention because of its potential for a fast-growing market demand. The applicability ranges from flavor enhancers, animal feed additives and ingredients in cosmetic to specialty nutrients in pharmaceutical and medical fields. Microbial fermentation is the major method for producing l-leucine by using Escherichia coli and Corynebacterium glutamicum as host bacteria. This review gives an overview of the metabolic pathway of l-leucine (i.e. production, import and export systems) and highlights the main regulatory mechanisms of operons in E. coli and C. glutamicum l-leucine biosynthesis. We summarize here the current trends in metabolic engineering techniques and strategies for manipulating l-leucine producing strains. Finally, future perspectives to construct industrially advantageous strains are considered with respect to recent advances in biology.

KEYWORDS

-Leucine biosynthesis; metabolic engineering; regulatory mechanisms; strain development

Title

Metabolic engineering of l-leucine production in Escherichia coli and Corynebacterium glutamicum: a review.

Author

Wang YY1, Xu JZ1,2, Zhang WG1.

Publish date

2019 Aug


Description :

L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1].