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Catalogue Number : BD-P0632
Specification : 95.0%(HPLC)
CAS number : 63-68-3
Formula : C5H11NO2S
Molecular Weight : 149.2
Volume : 1000mg

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L-Methionine (Synonyms: (S)-2-Amino-4-(methylthio)butanoic acid)

Methionine is one of nine essential amino acids in humans (provided by food), Methionine is required for growth and tissue repair. A sulphur-containing amino acid, methionine improves the tone and pliability of skin, hair, and strengthens nails. Involved in many detoxifying processes, sulphur provided by methionine protects cells from pollutants.

Catalogue Number


Analysis Method





Molecular Weight




Botanical Source

Structure Type





S-methionine/(S)-2-amino-4-(methylthio)-Butanoic acid/L-α-Amino-γ-methylmercaptobutyric acid/Methionine (VAN)/(L)-Methionine/Met-bNA/2-Amino-4-methylthiobutanoic acid (S)-/L-a-Amino-g-methylmercaptobutyric Acid/Methionine, L- (8CI)/(2S)-2-amino-4-(methylsulfanyl)butanoic acid/Methionine (USP)/N-L-Methionyl-2-naphthylamine/N-L-Methionyl-2-naphthylamin/L-Methionyl b-naphthylamide/(2S)-2-Amino-4-methylsulfanylbutanoic acid/Methionine/Methionine b-naphthylamide/2-Amino-4-(methylthio)butyric acid, (S)-/L-Methionine/l-met/(S)-(-)-Methionine/Met/L-Methionine (JP15)/H-Met-OH/L-Methionin



1.2±0.1 g/cm3



Flash Point

139.4±26.5 °C

Boiling Point

306.9±37.0 °C at 760 mmHg

Melting Point

284 °C (dec.)(lit.)


InChl Key


WGK Germany


HS Code Reference

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

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provides coniferyl ferulate(CAS#:63-68-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.




Chitin amendment is an agricultural management strategy for controlling soil-borne plant disease. We previously reported an exponential decrease in chitin added to incubated upland soil. We herein investigated the transition of the bacterial community structure in chitin-degrading soil samples over time and the characteristics of chitinolytic bacteria in order to elucidate changes in the chitinolytic bacterial community structure during chitin degradation. The addition of chitin to soil immediately increased the population of bacteria in the genus Streptomyces, which is the main decomposer of chitin in soil environments. Lysobacter, Pseudoxanthomonas, Cellulosimicrobium, Streptosporangium, and Nonomuraea populations increased over time with decreases in that of Streptomyces. We isolated 104 strains of chitinolytic bacteria, among which six strains were classified as Lysobacter, from chitin-treated soils. These results suggested the involvement of Lysobacter as well as Streptomyces as chitin decomposers in the degradation of chitin added to soil. Lysobacter isolates required yeast extract or casamino acid for significant growth on minimal agar medium supplemented with glucose. Further nutritional analyses demonstrated that the six chitinolytic Lysobacter isolates required methionine (Met) to grow, but not cysteine or homocysteine, indicating Met auxotrophy. Met auxotrophy was also observed in two of the five type strains of Lysobacter spp. tested, and these Met auxotrophs used d-Met as well as l-Met. The addition of Met to incubated upland soil increased the population of Lysobacter. Met may be a factor increasing the population of Lysobacter in chitin-treated upland soil.


Lysobacter; Streptomyces; chitin; d-Met; methionine


Transition of the Bacterial Community and Culturable Chitinolytic Bacteria in Chitin-treated Upland Soil: From Streptomyces to Methionine-auxotrophic Lysobacter and Other Genera.


Iwasaki Y1, Ichino T1, Saito A1.

Publish date





Two consecutive trials were carried out to study the effects of dietary supplementation of rumen-protected methionine (RPM) on nutrient digestibility, nitrogen (N) metabolism (Trial 1), and consequently the nitrous oxide (N2 O) emissions from urine in beef cattle (Trial 2). Eight 24-month-old castrated Simmental bulls with liveweights of 494 ± 28 kg, and four levels of dietary supplementation of RPM at 0, 10, 20, and 30 g head-1 d-1 , were allocated in a replicated 4 × 4 Latin square for Trial 1 and the N2 O emissions from the urine samples collected in Trial 1 were measured using a static incubation technique in Trial 2.

Supplementation of RPM at 0, 10, 20, and 30 g head-1 d-1 to a basal ration deficient in methionine (Met) did not affect the apparent digestibility of dry matter, organic matter, neutral detergent fiber, or acid detergent fiber (P > 0.05), but decreased the urinary excretions of total N (P < 0.05) and urea (P < 0.001), increased the ratio of N retention / digested N (P < 0.05) in beef cattle, and decreased the estimated cattle urine N2 O-N emissions by 19.5%, 23.4%, and 32.6%, respectively (P < 0.001). CONCLUSION: Supplementation of RPM to Met-deficient rations was effective in improving the utilization rate of dietary N and decreasing the N2 O emissions from urine in beef cattle. © 2019 Society of Chemical Industry. © 2019 Society of Chemical Industry.


beef cattle; methionine; nitrogen excretion; nitrous oxide; urine


Dietary supplementation of rumen-protected methionine decreases the nitrous oxide emissions of urine of beef cattle through decreasing urinary excretions of nitrogen and urea.


Zhao Y1, Rahman MS1, Zhao G1, Bao Y1, Zhou K1.

Publish date

2020 Mar 15




This study was conducted to explore the effects of sulfur containing amino acids on redox status and morphological parameters in the rat ileum tissue. Male Wistar albino rats were randomly divided into the following groups: Group K (saline (1 ml/day, i.p.)), Group M (methionine (0.8 mmol/kg/day, i.p.)), Group C (methionine (0.8 mmol/kg/day) + L-cysteine (7 mg/kg/day), i.p.) and Group N (methionine (0.8 mmol/kg/day) + N-acetyl-L-cysteine (50 mg/kg/day), i.p.). Activities of antioxidant enzymes in the ileum were analyzed to profile oxidative status. Morphometric analysis included measurement of villus height (μm), tunica mucosa thickness (μm), tunica muscularis thickness (μm), the total thickness of the ileal wall (μm) and the number of cells in the lamina propria (per 0.1 mm2 of tissue). Results showed that methionine treatment reduced the activity of antioxidant enzymes (SOD, GPx, CAT) and the GSH content compared to the control group (p > 0.05). The application of methionine reduced the following parameters statistically significant compared to the control group: length of the ileal villi (p < 0.01), tunica mucosa thickness (p < 0.01), and ileal wall thickness (p < 0.01). We concluded that methionine induced the changes in the gut redox status, which implied oxidative stress occurrence. L-cysteine and N-acetyl-L-cysteine both exhibited antioxidant properties.


Effects of subchronic methionine stimulation on oxidative status and morphological changes in the rat ileum.


Todorovic D1, Stojanovic M, Scepanovic L, Mitrovic D, Scepanovic V, Scepanovic R, Scepanovic T, Labudovic-Borovic M, Dragutinovic V, Borozan N, Djuric D.

Publish date

2019 Nov