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Lehmannine

$1,030

  • Brand : BIOFRON

  • Catalogue Number : AV-C10444

  • Specification : 98%

  • CAS number : 58480-54-9

  • Formula : C15H22N2O

  • Molecular Weight : 246.4

  • PUBCHEM ID : 3041752

  • Volume : 5mg

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Catalogue Number

AV-C10444

Analysis Method

HPLC,NMR,MS

Specification

98%

Storage

2-8°C

Molecular Weight

246.4

Appearance

Cryst.

Botanical Source

Structure Type

Alkaloids

Category

Standards;Natural Pytochemical;API

SMILES

C1CC2CN3C(C=CCC3=O)C4C2N(C1)CCC4

Synonyms

Lehmanine/Matridin-15-one,12,13-didehydro/12,13-Didehydromatridin-15-one

IUPAC Name

(1S,2R,9S,17S)-7,13-diazatetracyclo[7.7.1.02,7.013,17]heptadec-3-en-6-one

Applications

Density

Solubility

Flash Point

Boiling Point

Melting Point

InChl

InChI=1S/C15H22N2O/c18-14-7-1-6-13-12-5-3-9-16-8-2-4-11(15(12)16)10-17(13)14/h1,6,11-13,15H,2-5,7-10H2/t11-,12+,13+,15-/m0/s1

InChl Key

WUVYENIUARJBNM-JLNYLFASSA-N

WGK Germany

RID/ADR

HS Code Reference

2933990000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:58480-54-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

18506910

Abstract

A high-performance liquid chromatographic (HPLC) method for determining lehmannine (LMN) in rat plasma was developed for application in the pharmacokinetics study. The plasma was deproteinized with acetonitrile that contained an internal standard and was separated from the aqueous layer by adding sodium chloride. The HPLC assay was carried out using a VP-ODS column at 40 degrees C. The mobile phase was acetonitrile-0.02 mol/L ammonium acetate buffer-triethylamine (35:65:0.04, v/v/v). The flow rate was 1.0 mL/min. The detection wavelength was set at 220 nm. The method was used to determine the concentration-time profiles of LMN in the plasma following oral administration or bolus injection of LMN aqueous solution. The pharmacokinetic parameters of LMN were calculated for the first time by Drug and Statistics 1.0 program.

Title

An HPLC method for the determination and pharmacokinetic study of lehmannine in rat plasma.

Author

Zhao G1, Du W, Wei Y, Qin H, Wu X.

Publish date

2008 Oct