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Licoisoflavone B

$1,568

  • Brand : BIOFRON

  • Catalogue Number : BD-P0954

  • Specification : 98.5%(HPLC&TLC)

  • CAS number : 66056-30-2

  • Formula : C20H16O6

  • Molecular Weight : 352.34

  • PUBCHEM ID : 5481234

  • Volume : 25mg

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Catalogue Number

BD-P0954

Analysis Method

HPLC,NMR,MS

Specification

98.5%(HPLC&TLC)

Storage

2-8°C

Molecular Weight

352.34

Appearance

Yellow powder

Botanical Source

Structure Type

Flavonoids

Category

Standards;Natural Pytochemical;API

SMILES

CC1(C=CC2=C(O1)C=CC(=C2O)C3=COC4=CC(=CC(=C4C3=O)O)O)C

Synonyms

4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(5-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-/Lico-iso-flavone B/Licoisoflavone B/5,5',7-Trihydroxy-2',2'-dimethyl-2'H,4H-3,6'-bichromen-4-one

IUPAC Name

5,7-dihydroxy-3-(5-hydroxy-2,2-dimethylchromen-6-yl)chromen-4-one

Applications

Licoisoflavone B, an isoflavone, mainly derived from Glycyrrhiza uralensis Fisch.[1]. Licoisoflavone B inhibits lipid peroxidation with an IC50 of 2.7 μM.

Density

1.4±0.1 g/cm3

Solubility

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

Flash Point

215.1±23.6 °C

Boiling Point

588.9±50.0 °C at 760 mmHg

Melting Point

180-183℃

InChl

InChI=1S/C20H16O6/c1-20(2)6-5-12-15(26-20)4-3-11(18(12)23)13-9-25-16-8-10(21)7-14(22)17(16)19(13)24/h3-9,21-23H,1-2H3

InChl Key

KIZPADOTOCPASX-UHFFFAOYSA-N

WGK Germany

RID/ADR

HS Code Reference

2914400000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:66056-30-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

31101652

Abstract

Specific characteristics of the male Achroia grisella acoustic mating signal determine a male’s attractiveness toward females. These features are genetically variable in populations, and mapping experiments have been used to identify loci contributing to song variation, and understand the evolutionary forces acting on this important sexual trait. Here we built on this foundation and carried out QTL (Quantitative Trait Locus) mapping using >1,000 recombinant individuals, genotyping this large cohort at thousands of sequence-based markers covering the entire collection of 30 A. grisella chromosomes. This dense marker set, coupled with our development of an annotated, draft genome of A. grisella, allowed us to link >3,000 genome scaffolds, >10,000 predicted genes, and close to 275Mb of genome sequence to chromosomes. Our QTL mapping confirmed a fraction of the QTL identified in a previous study, and additionally revealed novel loci. Collectively, QTL explained only small fractions of the phenotypic variance, suggesting many more causative factors remain below the detection threshold of our study. A surprising, and ultimately challenging feature of our study was the low level of intrachromosomal recombination present in our mapping population. This led to difficulty ordering markers along linkage groups, necessitating a chromosome-by-chromosome mapping approach, rather than true interval mapping, and precluded confident ordering/orienting of scaffolds along each chromosome. Nonetheless, our study increased the genomic resources available for the A. grisella system. Enabled by ever more powerful technologies, future investigators will be able to leverage our data to provide more detailed genetic dissection of male song variation in A. grisella.

KEYWORDS

QTL, male song, genome assembly, genotyping-by-sequencing

Title

Quantitative Genetic Mapping and Genome Assembly in the Lesser Wax Moth Achroia grisella

Author

Boryana S. Koseva, Jennifer L. Hackett, Yihong Zhou, Bethany R. Harris, John K. Kelly, Michael D. Greenfield, Jennifer M. Gleason, Stuart J. Macdonald

Publish date

2019 Jul;

PMID

20145744

Abstract

Purpose: To determine factors associated with Canadian physiotherapists’ interest in undertaking continuing education in various cardiorespiratory content areas and their willingness to complete a portion of study within each of these content areas via computer-assisted learning (CAL).

Methods: In a six-page mailed questionnaire, 1,426 potential participants were asked to indicate their interest in 11 cardiorespiratory content areas, their continuing-education preferences, and their access and willingness to do continuing education by CAL. Demographic data were also collected from respondents.

Results: Respondents included 285 physiotherapists from cardiorespiratory interest groups (CRGs) and 447 from the licensing bodies’ sample (overall response rate = 56%). Physiotherapists in public employment and practice areas other than orthopaedics had increased interest in all cardiorespiratory content areas except Exercise Physiology. Membership in a CRG increased their likelihood to be willing to learn the cardiorespiratory content area via CAL.

Conclusions: In developing content and determining the accessibility of cardiorespiratory continuing education, educators should consider the type of employer and area of practice of interested attendees as well as the lack of willingness to use CAL by those not involved in CRGs.

KEYWORDS

computer-assisted learning, physical therapists, continuing education, distance learning, Internet

Title

Factors Associated with Physiotherapists’ Interest in Cardiorespiratory Continuing Education Using Computer-Assisted Learning: A Survey

Author

W. Darlene Reid, Susan J. Stanton, L. Cheryle Kelm

Publish date

2008 Winter;

PMID

22665994

Abstract

Introduction
The prescription of physical activity for hospitalized patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) can be complicated by the presence of comorbidities. The current research aimed to synthesize the relevant literature on the benefits of exercise for people with multimorbidities who experience an AECOPD, and ask: What are the parameters and outcomes of exercise in AECOPD and in conditions that are common comorbidities as reported by systematic reviews (SRs)?

Methods
An SR was performed using the Cochrane Collaboration protocol. Nine electronic databases were searched up to July 2011. Articles were included if they (1) described participants with AECOPD, chronic obstructive pulmonary disease (COPD), or one of eleven common comorbidities, (2) were an SR, (3) examined aerobic training (AT), resistance training (RT), balance training (BT), or a combination thereof, (4) included at least one outcome of fitness, and (5) compared exercise training versus control/sham.

Results
This synthesis examined 58 SRs of exercise training in people with AECOPD, COPD, or eleven chronic conditions commonly associated with COPD. Meta-analyses of endurance (aerobic or exercise capacity, 6-minute walk distance – 6MWD) were shown to significantly improve in most conditions (except osteoarthritis, osteoporosis, and depression), whereas strength was shown to improve in five of the 13 conditions searched: COPD, older adults, heart failure, ischemic heart disease, and diabetes. Several studies of different conditions also reported improvements in quality of life, function, and control or prevention outcomes. Meta-analyses also demonstrate that exercise training decreases the risk of mortality in older adults, and those with COPD or ischemic heart disease. The most common types of training were AT and RT. BT and functional training were commonly applied in older adults. The quality of the SRs for most conditions was moderate to excellent (>65%) as evaluated by AMSTAR scores.

Conclusion
In summary, this synthesis showed evidence of significant benefits from exercise training in AECOPD, COPD, and conditions that are common comorbidities. A broader approach to exercise and activity prescription in pulmonary rehabilitation may induce therapeutic benefits to ameliorate clinical sequelae associated with AECOPD and comorbidities such as the inclusion of BT and functional training.

KEYWORDS

pulmonary disease, chronic obstructive, comorbidity, exercise, physical fitness

Title

Exercise prescription for hospitalized people with chronic obstructive pulmonary disease and comorbidities: a synthesis of systematic reviews

Author

W Darlene Reid, Cristiane Yamabayashi, Donna Goodridge, Frank Chung, Michael A Hunt, Darcy D Marciniuk, Dina Brooks, Yi-Wen Chen, Alison M Hoens, Pat G Camp

Publish date

2012