This product is isolated and purified from the roots of Liriope muscari
《Pharmaceutical Care and Research》 2007-06 Preparation of liriope muscari baily saponins C solid lipid nanoparticles[Reference: WebLink]To prepare Liriope muscari baily saponins C solid lipid nanoparticles(DT-13-SLN) and to assess their physico-chemical characteristics.METHODS AND RESULTS:DT-13-SLN was prepared by the emulsification-solvent evaporation method.The formulation and the preparation technology of Liriope muscari baily saponins C solid lipid nanoparticles were optimized by the orthogonal design,the morphology was examined by the transmission electron microscope.The diameter,entrapment efficiency,drug loading, zeta potential and stability of Liriope muscari baily saponins C solid lipid nanoparticles were investigated. The average diameter of Liriope muscari baily saponins C solid lipid nanoparticles was 128.8 nm,the zeta potential was-30.0 mV,the entrapment efficiency was 57.43% and the drug loading was 3.48%.There were no notable changes of the particle size and entrapment efficiency at 4 ℃ within one month.New substance was examined by differential scanning calorimetery(DSC) analysis of Liriope muscari baily saponins C solid lipid nanoparticles.CONCLUSIONS: Liriope muscari baily saponins C solid lipid nanoparticles shows a narrow particle size distribution and good stability.
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
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