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Lithosprmoside

$113

  • Brand : BIOFRON

  • Catalogue Number : BF-L2018

  • Specification : 98%

  • CAS number : 63492-69-3

  • Formula : C14H19NO8

  • Molecular Weight : 329.3

  • PUBCHEM ID : 10065132

  • Volume : 20mg

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Catalogue Number

BF-L2018

Analysis Method

HPLC,NMR,MS

Specification

98%

Storage

2-8°C

Molecular Weight

329.3

Appearance

White flocculent crystal

Botanical Source

Semiaquilegia adoxoides

Structure Type

Others

Category

Standards;Natural Pytochemical;API

SMILES

C1=CC(=CC#N)C(C(C1O)O)OC2C(C(C(C(O2)CO)O)O)O

Synonyms

(2Z)-[(4R,5S,6S)-6-(β-D-Glucopyranosyloxy)-4,5-dihydroxy-2-cyclohexen-1-ylidene]acetonitrile/Lithospermosid/lithosprMoside/Lithospermoside/Acetonitrile, 2-[(4R,5S,6S)-6-(β-D-glucopyranosyloxy)-4,5-dihydroxy-2-cyclohexen-1-ylidene]-, (2Z)-/griffonin

IUPAC Name

(2Z)-2-[(4R,5S,6S)-4,5-dihydroxy-6-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxycyclohex-2-en-1-ylidene]acetonitrile

Density

1.6±0.1 g/cm3

Solubility

Methanol; Water

Flash Point

354.4±31.5 °C

Boiling Point

662.4±55.0 °C at 760 mmHg

Melting Point

271ºC (DEC.)

InChl

InChI=1S/C14H19NO8/c15-4-3-6-1-2-7(17)9(18)13(6)23-14-12(21)11(20)10(19)8(5-16)22-14/h1-3,7-14,16-21H,5H2/b6-3+

InChl Key

WIIDBJNWXCWLKF-ZZXKWVIFSA-N

WGK Germany

RID/ADR

HS Code Reference

2938900000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:63492-69-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

PMID

11182495

Title

Lithospermoside from Bauhinia fassoglensis (Fabaceae).

Author

Fort DM1, Jolad SD, Nelson ST.

Publish date

2001 Apr


Description :

Anti-tumor promoting activity of polyphenols from Cowania mexicana and Coleogyne ramosissima. PUMID/DOI:10465331 Cancer Lett. 1999 Aug 23;143(1):5-13. Chemical investigation on polyphenol-rich fractions of Cowania mexicana and Coleogyne ramosissima (Rosaceae) which showed significant inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA), has led to the characterization of 10 compounds including C-glucosidic ellagitannin monomers and dimers from the former plant, and 17 polyphenols including flavonoid glycosides from the latter. The effects of individual components and their analogues with related structures on the TPA-induced EBV-EA activation were then evaluated. Among the compounds isolated from C. mexicana, two C-glucosidic ellagitannins, alienanin B and stenophyllanin A and a nitrile glucoside (Lithospermoside), and among the constituents from C. ramosissima, two flavonoid glycosides, isorhamnetin 3-0-beta-D-glucoside and narcissin were revealed to possess strong inhibitory effects on EVB-EA activation, the potencies of which were either comparable to or stronger than that of a green tea polyphenol, (-)-epigallocatechin gallate. These polyphenols except for nitrile glucoside, which was not tested owing to an insufficient amount, were also found to exhibit anti-tumor promoting activity in two-stage mouse skin carcinogenesis using 7,12-dimethylbenz[a]anthracene (DMBA) and TPA.