Anti-ulcer effect / Stomach ulcer
Protective Effect of Lobetyolin on Gastric Mucosa of Experimental Gastric Ulcer in Rats PUMID/DOI：无 Journal of Emergency in Traditional Chinese Medicine, 2008, 17(7):963-4. "To study the protective effect of Lobetyolin on gastric mucosa of experimental gastric ulcer induced by ethanol in rats.Methods:The gastric ulcer model was established in rats by inducing ethanol.The index of ulcer was measured;the levels of Gas and 6-K-PGF1αwere examined by the method of radioimmunity;the level of EGF was measured by ELISA.Results:As compared with model group,in Lobetyolin small dose group,the index of ulcer was markedly decreased,the level of Gas was decreased while the level of 6-K-PGF1αwas increased.In the degree,the level of EGF was increased.Conclusion:Lobetyolin has a protective role in gastric mucosa injury,and the mechanism may be relate to the increase in level of 6-K-PGF1αand the inhibition the excretion of gastric acid and EGF. || ||"
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