This product is isolated and purified from the root of Lindera strychnifolia
(2Z)-2-[(2E)-1-Hydroxy-3-phenyl-2-propen-1-ylidene]-4-methoxy-4-cyclopentene-1,3-dione/4-Cyclopentene-1,3-dione, 2-[(2E)-1-hydroxy-3-phenyl-2-propen-1-ylidene]-4-methoxy-, (2Z)-
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
489.6±45.0 °C at 760 mmHg
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Personal Projective Equipment
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provides coniferyl ferulate(CAS#:19956-53-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate
We investigated the seasonal spreading and transport of buoyant plume in the shelf off Kochi using Finite Volume Community Ocean Model (FVCOM). The modelled river plume typically consisted of an offshore bulge and a coastal current. The spreading of the bulge extended up to a distance of 19 km from inlet during the summer monsoon to <10 km in the spring inter-monsoon. The Kelvin number varied between 0.1 and 0.9 which revealed that the plume exhibited both the features of small and large scale plumes, resulting in a highly complicated plume pattern. During the southwest monsoon the plume fringe twisted towards the south, while during the northeast monsoon it twisted towards north according to the reversal of monsoonal winds. The fresh water transport with respect to coastal currents varied in accordance with seasonal river discharge such that the value peaked in the wet season and dropped in the dry season. During the non-realistic (no wind) condition the plume initiated barotropic and baroclinic flow, after which it was acted upon by earth’s rotation so that the plume propagated in the direction of Coriolis force (towards north), as geostrophic currents. The model run ‘with wind’ and ‘without wind’ condition revealed that in the shelf off Kochi the plume is transported in accordance with monsoonal winds/currents by nullifying the effect of earth’s rotation. The categorization of plume influenced area and realization of the direction of plume transport can be used for interpreting the dynamically and potentially active zones in the shelf off Kochi. Subject terms: Environmental impact, Physical oceanography
Seasonal spreading and transport of buoyant plumes in the shelf off Kochi, South west coast of India- A modeling approach
G. Seena,1,2 K. R. Muraleedharan,corresponding author1 C. Revichandran,1 S. Abdul Azeez,1 and Sebin John1,2
Both short and long interpregnancy intervals (IPI) are believed to present possible adverse conditions for fetal development. Short IPI has recently been associated with increased risk of autism, but whether long IPI increases risk for autism spectrum disorders (ASD) has not been thoroughly investigated. We investigated the association between short and long IPI in a Finnish population-based study.
This study was conducted in the Finnish Prenatal Study of Autism, which is based in a national birth cohort. Children born in Finland in 1987-2005 and diagnosed with ASD by 2007 were identified through the Finnish Hospital Discharge Register. 2,208 non-firstborn patients with ASD and 5,163 matched controls identified from the Finnish Medical Birth Register were included in the primary analysis. The association between IPI and ASD was determined using conditional logistic regression and adjusted for potential confounders.
Relative to births with an IPI of 24-59 months, those with the shortest IPI (<12 months) had an increased risk of ASD (OR [95% CI], 1.50 [1.28, 1.74]) in confounder-adjusted models, while the ORs (95% CI) for longer IPI births (60-119 months and ≥120 months) were 1.28 (1.08, 1.52) and 1.44 (1.12, 1.85), respectively. Conclusion This study provides evidence that risk of ASD is increased at long as well as short IPI.
autism spectrum disorders, autism, interpregnancy interval, interbirth interval, birth spacing
Increased Risk of Autism Spectrum Disorders at Short and Long Interpregnancy Intervals in Finland
Dr. Keely Cheslack-Postava, PhD, Ms. Auli Suominen, MSc, Ms. Elina Jokiranta, MA, Dr. Venla Lehti, MD, Dr. Ian W. McKeague, PhD, Dr. Andre Sourander, MD, and Dr. Alan S. Brown, MD
2015 Oct 1.
This study is an update of a systematic review of health-related quality-of-life (HRQOL) methodology reporting in non-small-cell lung cancer (NSCLC) randomized controlled trials (RCTs). The objective was to evaluate HRQOL methodology reporting over the last decade and its benefit for clinical decision making.
A MEDLINE systematic literature review was performed. Eligible RCTs implemented patient-reported HRQOL assessments and regular oncology treatments for newly diagnosed adult patients with NSCLC. Included studies were published in English from August 2002 to July 2010. Two independent reviewers evaluated all included RCTs.
Fifty-three RCTs were assessed. Of the 53 RCTs, 81% reported that there was no significant difference in overall survival (OS). However, 50% of RCTs that were unable to find OS differences reported a significant difference in HRQOL scores. The quality of HRQOL reporting has improved; both reporting of clinically significant differences and statistical testing of HRQOL have improved. A European Organisation for Research and Treatment of Cancer HRQOL questionnaire was used in 57% of the studies. However, reporting of HRQOL hypotheses and rationales for choosing HRQOL instruments were significantly less than before 2002 (P < .05). Conclusion The number of NSCLC RCTs incorporating HRQOL assessments has considerably increased. HRQOL continues to demonstrate its importance in RCTs, especially in those studies in which no OS difference is found. Despite the improved quality of HRQOL methodology reporting, certain aspects remain underrepresented. Our findings suggest need for an international standardization of HRQOL reporting similar to the CONSORT guidelines for clinical findings.
Health-Related Quality of Life in Non-Small-Cell Lung Cancer: An Update of a Systematic Review on Methodologic Issues in Randomized Controlled Trials
Lily Claassens, Jan van Meerbeeck, Corneel Coens, Chantal Quinten, Irina Ghislain, Elizabeth K. Sloan, Xin Shelly Wang, Galina Velikova, and Andrew Bottomley
2011 May 20;