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Lutein

$66

  • Brand : BIOFRON

  • Catalogue Number : AV-P12026

  • Specification : 98%

  • CAS number : 127-40-2

  • Formula : C40H56O2

  • Molecular Weight : 568.87

  • PUBCHEM ID : 5281243

  • Volume : 25mg

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Catalogue Number

AV-P12026

Analysis Method

HPLC,NMR,MS

Specification

98%

Storage

-20℃

Molecular Weight

568.87

Appearance

White crystalline powder

Botanical Source

Xanthophyll/Echinacea purpurea (Linn.) Moench

Structure Type

Other Terpenoids

Category

Standards;Natural Pytochemical;API

SMILES

CC1=C(C(CC(C1)O)(C)C)C=CC(=CC=CC(=CC=CC=C(C)C=CC=C(C)C=CC2C(=CC(CC2(C)C)O)C)C)C

Synonyms

Vegetable luteol/Xanthophyll/α-Carotene-3,3'-diol/β,ε-Carotene-3,3'-diol/all-trans-Lutein/Lutein/trans-Lutein/Vegetable lutein/(1R,4R)-4-{(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4R)-4-Hydroxy-2,6,6-trimethyl-1-cyclohexen-1-yl]-3,7,12,16-tetramethyl-1,3,5,7,9,11,13,15,17-octadecanonaen-1-yl}-3,5,5-trimethyl-2-cyclohexen-1-ol/(3R,3'R,6R)-4,5-Didehydro-5,6-dihydro-β,β-carotene-3,3'-diol/all-trans-(+)-Xanthophyll/(1R,4R)-4-{(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4R)-4-Hydroxy-2,6,6-trimethyl-1-cyclohexen-1-yl]-3,7,12,16-tetramethyl-1,3,5,7,9,11,13,15,17-octadecanonaen-1-yl}-3,5,5-trimethyl-2-cyclohexen-1-ol/β,β-Carotene-3,3'-diol, 4,5-didehydro-5,6-dihydro-, (3R,3'R,6R)-/β,ε-Carotene-3,3'-diol, (3R,3'R,6'R)-

IUPAC Name

(1R)-4-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1R,4R)-4-hydroxy-2,6,6-trimethylcyclohex-2-en-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5,5-trimethylcyclohex-3-en-1-ol

Density

1.0±0.1 g/cm3

Solubility

Dichloromethane; Ethyl Acetate

Flash Point

269.1±27.5 °C

Boiling Point

702.3±60.0 °C at 760 mmHg

Melting Point

183℃

InChl

InChl Key

WGK Germany

RID/ADR

HS Code Reference

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:127-40-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

29149368

Abstract

Lutein, a yellow xanthophyll carotenoid found in egg yolks and many colorful fruits and vegetables, has gained public health interest for its putative role in visual performance and reducing the risk of age-related macular degeneration. The National Academies of Sciences, Engineering and Medicine’s recommended Dietary Reference Intakes (DRIs) focus on preventing deficiency and toxicity, but there is a budding interest in establishing DRI-like guidelines for non-essential bioactives, like lutein, that promote optimal health and/or prevent chronic diseases. Lupton et al. developed a set of nine criteria to determine whether a bioactive is ready to be considered for DRI-like recommendations. These criteria include: (1) an accepted definition; (2) a reliable analysis method; (3) a food database with known amounts of the bioactive; (4) cohort studies; (5) clinical trials on metabolic processes; (6) clinical trials for dose-response and efficacy; (7) safety data; (8) systematic reviews and/or meta-analyses; (9) a plausible biological rationale. Based on a review of the literature supporting these criteria, lutein is ready to be considered for intake recommendations. Establishing dietary guidance for lutein would encourage the consumption of lutein-containing foods and raise public awareness about its potential health benefits.

KEYWORDS

Bioactives; Intake recommendations; Lutein; Macular degeneration; Visual performance.

Title

Dietary Guidance for Lutein: Consideration for Intake Recommendations Is Scientifically Supported

Author

Katherine M Ranard 1 , Sookyoung Jeon 1 , Emily S Mohn 2 , James C Griffiths 3 , Elizabeth J Johnson 2 , John W Erdman Jr 4 5

Publish date

2017 Dec

PMID

25109868

Abstract

The relationship between lutein and zeaxanthin and visual and cognitive health throughout the lifespan is compelling. There is a variety of evidence to support a role for lutein and zeaxanthin in vision. Lutein’s role in cognition has only recently been considered. Lutein and its isomer, zeaxanthin, are taken up selectively into eye tissue. Lutein is the predominant carotenoid in human brain tissue. Lutein and zeaxanthin in neural tissue may have biological effects that include antioxidation, anti-inflammation, and structural actions. In addition, lutein and zeaxanthin may be protective against eye disease because they absorb damaging blue light that enters the eye. In pediatric brains, the relative contribution of lutein to the total carotenoids is twice that found in adults, accounting for more than half the concentration of total carotenoids. The greater proportion of lutein in the pediatric brain suggests a need for lutein during neural development as well. In adults, higher lutein status is related to better cognitive performance, and lutein supplementation improves cognition. The evidence to date warrants further investigation into the role of lutein and zeaxanthin in visual and cognitive health throughout the lifespan.

KEYWORDS

carotenoid; cognition; lifespan; lutein; vision; zeaxanthin.

Title

Role of Lutein and Zeaxanthin in Visual and Cognitive Function Throughout the Lifespan

Author

Elizabeth J Johnson 1

Publish date

2014 Sep

PMID

29654731

Abstract

It is now widely accepted that nutrition during critical periods in early development, both pre- and postnatal, may have lifetime consequences in determining health or onset of major diseases in the adult life. Dietary carotenoids have shown beneficial health effects throughout the life cycle due to their potential antioxidant properties, their ability to serves as precursors of vitamin A and to the emerging signaling functions of their metabolites. The non-provitamin A carotenoids lutein and zeaxanthin are emerging as important modulators of infant and child visual and cognitive development, as well as critical effectors in the prevention and treatment of morbidity associated with premature births. This review provides a general overview of lutein and zeaxanthin metabolism in mammalian tissues and highlights the major advancements and remaining gaps in knowledge in regards to their metabolism and health effects during pre- and early post-natal development. Furthering our knowledge in this area of research will impact dietary recommendation and supplementation strategies aimed at sustaining proper fetal and infant growth.

KEYWORDS

Lutein; Mammalian development; Maternal milk; Placenta; Transport; Zeaxanthin.

Title

Lutein, Zeaxanthin and Mammalian Development: Metabolism, Functions and Implications for Health

Author

Elena Giordano 1 , Loredana Quadro 2

Publish date

2018 Jun 1


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