Catalogue Number
AV-P12026
Analysis Method
HPLC,NMR,MS
Specification
98%
Storage
-20℃
Molecular Weight
568.87
Appearance
White crystalline powder
Botanical Source
Xanthophyll/Echinacea purpurea （Linn.） Moench
Structure Type
Other Terpenoids
Category
Standards;Natural Pytochemical;API
SMILES
CC1=C(C(CC(C1)O)(C)C)C=CC(=CC=CC(=CC=CC=C(C)C=CC=C(C)C=CC2C(=CC(CC2(C)C)O)C)C)C
Synonyms
Vegetable luteol/Xanthophyll/α-Carotene-3,3'-diol/β,ε-Carotene-3,3'-diol/all-trans-Lutein/Lutein/trans-Lutein/Vegetable lutein/(1R,4R)-4-{(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4R)-4-Hydroxy-2,6,6-trimethyl-1-cyclohexen-1-yl]-3,7,12,16-tetramethyl-1,3,5,7,9,11,13,15,17-octadecanonaen-1-yl}-3,5,5-trimethyl-2-cyclohexen-1-ol/(3R,3'R,6R)-4,5-Didehydro-5,6-dihydro-β,β-carotene-3,3'-diol/all-trans-(+)-Xanthophyll/(1R,4R)-4-{(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4R)-4-Hydroxy-2,6,6-trimethyl-1-cyclohexen-1-yl]-3,7,12,16-tetramethyl-1,3,5,7,9,11,13,15,17-octadecanonaen-1-yl}-3,5,5-trimethyl-2-cyclohexen-1-ol/β,β-Carotene-3,3'-diol, 4,5-didehydro-5,6-dihydro-, (3R,3'R,6R)-/β,ε-Carotene-3,3'-diol, (3R,3'R,6'R)-
IUPAC Name
(1R)-4-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1R,4R)-4-hydroxy-2,6,6-trimethylcyclohex-2-en-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5,5-trimethylcyclohex-3-en-1-ol
Density
1.0±0.1 g/cm3
Solubility
Dichloromethane; Ethyl Acetate
Flash Point
269.1±27.5 °C
Boiling Point
702.3±60.0 °C at 760 mmHg
Melting Point
183℃
InChl
InChl Key
WGK Germany
RID/ADR
HS Code Reference
Personal Projective Equipment
Correct Usage
For Reference Standard and R&D, Not for Human Use Directly.
Meta Tag
provides coniferyl ferulate(CAS#:127-40-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate
No Technical Documents Available For This Product.
29149368
Lutein, a yellow xanthophyll carotenoid found in egg yolks and many colorful fruits and vegetables, has gained public health interest for its putative role in visual performance and reducing the risk of age-related macular degeneration. The National Academies of Sciences, Engineering and Medicine’s recommended Dietary Reference Intakes (DRIs) focus on preventing deficiency and toxicity, but there is a budding interest in establishing DRI-like guidelines for non-essential bioactives, like lutein, that promote optimal health and/or prevent chronic diseases. Lupton et al. developed a set of nine criteria to determine whether a bioactive is ready to be considered for DRI-like recommendations. These criteria include: (1) an accepted definition; (2) a reliable analysis method; (3) a food database with known amounts of the bioactive; (4) cohort studies; (5) clinical trials on metabolic processes; (6) clinical trials for dose-response and efficacy; (7) safety data; (8) systematic reviews and/or meta-analyses; (9) a plausible biological rationale. Based on a review of the literature supporting these criteria, lutein is ready to be considered for intake recommendations. Establishing dietary guidance for lutein would encourage the consumption of lutein-containing foods and raise public awareness about its potential health benefits.
Bioactives; Intake recommendations; Lutein; Macular degeneration; Visual performance.
Dietary Guidance for Lutein: Consideration for Intake Recommendations Is Scientifically Supported
Katherine M Ranard 1 , Sookyoung Jeon 1 , Emily S Mohn 2 , James C Griffiths 3 , Elizabeth J Johnson 2 , John W Erdman Jr 4 5
2017 Dec
25109868
The relationship between lutein and zeaxanthin and visual and cognitive health throughout the lifespan is compelling. There is a variety of evidence to support a role for lutein and zeaxanthin in vision. Lutein’s role in cognition has only recently been considered. Lutein and its isomer, zeaxanthin, are taken up selectively into eye tissue. Lutein is the predominant carotenoid in human brain tissue. Lutein and zeaxanthin in neural tissue may have biological effects that include antioxidation, anti-inflammation, and structural actions. In addition, lutein and zeaxanthin may be protective against eye disease because they absorb damaging blue light that enters the eye. In pediatric brains, the relative contribution of lutein to the total carotenoids is twice that found in adults, accounting for more than half the concentration of total carotenoids. The greater proportion of lutein in the pediatric brain suggests a need for lutein during neural development as well. In adults, higher lutein status is related to better cognitive performance, and lutein supplementation improves cognition. The evidence to date warrants further investigation into the role of lutein and zeaxanthin in visual and cognitive health throughout the lifespan.
carotenoid; cognition; lifespan; lutein; vision; zeaxanthin.
Role of Lutein and Zeaxanthin in Visual and Cognitive Function Throughout the Lifespan
Elizabeth J Johnson 1
2014 Sep
29654731
It is now widely accepted that nutrition during critical periods in early development, both pre- and postnatal, may have lifetime consequences in determining health or onset of major diseases in the adult life. Dietary carotenoids have shown beneficial health effects throughout the life cycle due to their potential antioxidant properties, their ability to serves as precursors of vitamin A and to the emerging signaling functions of their metabolites. The non-provitamin A carotenoids lutein and zeaxanthin are emerging as important modulators of infant and child visual and cognitive development, as well as critical effectors in the prevention and treatment of morbidity associated with premature births. This review provides a general overview of lutein and zeaxanthin metabolism in mammalian tissues and highlights the major advancements and remaining gaps in knowledge in regards to their metabolism and health effects during pre- and early post-natal development. Furthering our knowledge in this area of research will impact dietary recommendation and supplementation strategies aimed at sustaining proper fetal and infant growth.
Lutein; Mammalian development; Maternal milk; Placenta; Transport; Zeaxanthin.
Lutein, Zeaxanthin and Mammalian Development: Metabolism, Functions and Implications for Health
Elena Giordano 1 , Loredana Quadro 2
2018 Jun 1
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