Shipping to France We Offer Worldwide Shipping
Login Wishlist

Macelignan, (+)-

$105

  • Brand : BIOFRON

  • Catalogue Number : AV-P10572

  • Specification : 98%

  • CAS number : 107534-93-0

  • Formula : C20H24O4

  • Molecular Weight : 328.40

  • PUBCHEM ID : 10404245

  • Volume : 20mg

Available on backorder

Quantity
Checkout Bulk Order?

Catalogue Number

AV-P10572

Analysis Method

HPLC,NMR,MS

Specification

98%

Storage

2-8°C

Molecular Weight

328.40

Appearance

White crystalline powder

Botanical Source

Schisandrachinensls(Turcz,)Baill/Myristica fragrans (nutmeg), bark of Kadsura longipedunculata and Schizandra sphenanthera

Structure Type

Lignanoids

Category

Standards;Natural Pytochemical;API

SMILES

CC(CC1=CC2=C(C=C1)OCO2)C(C)CC3=CC(=C(C=C3)O)OC

Synonyms

Phenol, 4-[(2S,3R)-4-(1,3-benzodioxol-5-yl)-2,3-dimethylbutyl]-2-methoxy-/HMS2219A18/(+)-Anwulignan/Macelignan/4-[(2S,3R)-4-(1,3-Benzodioxol-5-yl)-2,3-dimethylbutyl]-2-methoxyphenol/austrobailignan 6/Anwuligan/Macelignan, (+)-

IUPAC Name

4-[(2S,3R)-4-(1,3-benzodioxol-5-yl)-2,3-dimethylbutyl]-2-methoxyphenol

Applications

Macelignan(Anwuligan) is a natural compound isolated from Myristica fragrans Houtt; possesses therapeutic potentials against neurodegenerative diseases with oxidative stress and neuroinflammation.IC50 value:Target: in vitro: Macelignan significantly attenuated the ROS production and neurotoxicity induced by glutamate in HT22 cell [1]. At 24 h of biofilm growth, S. mutans, A. viscosus and S. sanguis biofilms were reduced by up to 30%, 30% and 38%, respectively, after treatment with 10 microg/mL macelignan for 5 min [2]. Cisplatin-induced phosphorylation of c-Jun N-terminal kinase1/2 (JNK1/2) and extracellular signal-regulated kinase1/2 (ERK1/2) was abrogated by pretreatment with macelignan, however, that of p38 was not significantly affected [3].in vivo: Macelignan attenuated the expression of phosphorylated c-Jun in cisplatin-treated mice [3]. Daily administration of macelignan reduced the spatial memory impairments induced by the chronic LPS infusions [4].

Density

1.159

Solubility

Methanol; Ethyl Acetate

Flash Point

236℃

Boiling Point

467.0±40.0 °C at 760 mmHg

Melting Point

70-71℃

InChl

InChl Key

QDDILOVMGWUNGD-UONOGXRCSA-N

WGK Germany

RID/ADR

HS Code Reference

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:107534-93-0) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

No Article Available.