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Macusine B

$1,216

Brand : BIOFRON
Catalogue Number : BN-B1550
Specification : 98%(HPLC)
CAS number : 6792-07-0
Formula : C20H25N2O+
Molecular Weight : 309.4
PUBCHEM ID : 16192
Volume : 5mg

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Catalogue Number

BN-B1550

Analysis Method

Specification

98%(HPLC)

Storage

2-8°C

Molecular Weight

309.4

Appearance

Botanical Source

Structure Type

Category

SMILES

CC=C1C[N+]2(C3CC1C(C2CC4=C3NC5=CC=CC=C45)CO)C

Synonyms

Sarpagan-4-ium, 17-hydroxy-4-methyl-, (4α)-/(4α,19E)-17-Hydroxy-4-methylsarpagan-4-ium/(4a)-17-Hydroxy-4-methylsarpaganium

IUPAC Name

(15-ethylidene-17-methyl-3-aza-17-azoniapentacyclo[12.3.1.02,10.04,9.012,17]octadeca-2(10),4,6,8-tetraen-13-yl)methanol

Density

Solubility

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

Flash Point

Boiling Point

Melting Point

InChl

InChl Key

KRTATNOTKFNEFT-UHFFFAOYSA-N

WGK Germany

RID/ADR

HS Code Reference

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:6792-07-0) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

27035053

Abstract

Sarpagine-related indole alkaloids (-)-hydroxygardnerine, (+)-hydroxygardnutine, (-)-gardnerine, (+)-(E)-16-epi-normacusine B, and (-)-koumine were divergently synthesized via a common intermediate possessing a piperidine ring with an exocyclic (E)-ethylidene side chain, which was constructed by a gold(I)-catalyzed 6-exo-dig cyclization strategy.

Title

Asymmetric Total Synthesis of Sarpagine-Related Indole Alkaloids Hydroxygardnerine, Hydroxygardnutine, Gardnerine, (E)-16-epi-Normacusine B, and Koumine

Author

Mariko Kitajima 1, Keisuke Watanabe 1, Hiroyuki Maeda 1, Noriyuki Kogure 1, Hiromitsu Takayama 1

Publish date

2016 Apr 15

PMID

2414730

Title

RFLP for the human apolipoprotein B gene: IV;MspI.

Author

L Priestley, T Knott, S Wallis, L Powell, R Pease, and J Scott

Publish date

1985 Sep 25;

PMID

28718100

Abstract

Purpose
Cardiopulmonary bypass (CPB) induces a significant inflammatory response that may increase the risk for delirium. We hypothesized that exposure to CPB during coronary artery bypass grafting surgery would correlate with an increased risk of delirium and would be associated with several other outcomes.

Methods
We reviewed clinical data from two databases at our medical center, the Cardiac Surgery Perioperative Outcomes Database and the Society of Thoracic Surgeons Database. Patients undergoing elective coronary artery bypass grafting surgery (on-pump and off-pump) from November 1, 2009 to September 30, 2015 were included in the study. Delirium was defined as any positive CAM-ICU exam following surgery during the ICU course. We performed logistic regression to isolate the association between CPB exposure and delirium adjusted for predetermined risk factors and potential confounders.

Results
During the study period, a total of 2,280 patients underwent elective coronary artery bypass grafting surgery with 384 patients (16.9%) exposed to CPB. Delirium was diagnosed in 451 patients (19.8%). CPB exposure demonstrated a significant independent association with delirium (P = 0.002). The adjusted relative risk (RR) of delirium was 2.18 (95% CI, 1.39 to 3.07; P = 0.002) among patients exposed to CPB for 142 minutes (90th percentile of CPB duration), compared to a RR of only 1.51 (95% CI, 0.92 to 2.29; P = 0.10) for those on CPB for 54 minutes (10th percentile).

Conclusions
CPB use and duration of use were associated with an increased risk of delirium in patients undergoing coronary artery bypass grafting surgery.

Title

Risk factors for delirium after cardiac surgery: an historical cohort study outlining the influence of cardiopulmonary bypass

Publish date

2017 Nov 17.