Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
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136-138℃ (methanol )
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provides coniferyl ferulate(CAS#:93697-42-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate
Conventional techniques for single-base resolution mapping of epigenetic modifications of DNA such as 5-hydroxymethylcytosine (5hmC) rely on the sequencing of bisulfite-modified DNA. Here we present an alternative approach called SCL-exo which combines selective chemical labeling (SCL) of 5hmC in genomic DNA with exonuclease (exo) digestion of the bead-trapped modified DNA molecules. Associated with a straightforward bioinformatic analysis, this new procedure provides an unbiased and fast method for mapping this epigenetic mark at high resolution. Implemented on mouse genomic DNA from in vitro-differentiated neural precursor cells, SCL-exo sheds light on an intrinsic lack of conservation of hydroxymethylated CpGs across vertebrates.
Electronic supplementary material
The online version of this article (doi:10.1186/s13059-016-0919-y) contains supplementary material, which is available to authorized users.
5-hydroxymethylcytosine, 5hmC, Single-CpG resolution, Selective chemical labeling
Single-CpG resolution mapping of 5-hydroxymethylcytosine by chemical labeling and exonuclease digestion identifies evolutionarily unconserved CpGs as TET targets
Aurelien A. Serandour, Stephane Avner, Elise A. Mahe, Thierry Madigou, Sylvain Guibert, Micha?l Weber, and Gilles Salbertcorresponding author
The title compound, Sr0.6Ba0.4Nb2O6 (strontium barium niobium oxide), belongs to the group of strontium-barium niobates with varying composition of Sr and Ba. Their general formula can be written as SrxBa1 – xNb2O6. Below the Curie temperature, T c, these materials indicate ferroelectric properties. The Curie temperature for SBN60 is equal to 346±0.5?K so the structure is in the ferroelectric phase at the measurement temperature of 100?K. Characteristic for this family of compounds is the packing along the z-axis. The NbO6 corner-sharing octahedra surround three types of vacancy tunnels with pentagonal, square and triangular shapes. The Sr2+ ions partially occupy two unique sites, the first one located inside the pentagon and the second one in the square tunnels. Consequently, they are situated on the mirror plane and the intersection of two glide planes, respectively. The site inside the pentagonal tunnel is additionally disordered so that the same position is shared by Ba2+ and Sr2+ ions whereas another part of the Ba2+ ion occupies a different position (relative occupancies 0.43:0.41:0.16). One of the NbV atoms and three of the O2? ions occupy general positions. The second NbV atom is located on the intersection of the mirror planes. Two remaining O2? ions are located on the same mirror plane. Only the NbV atom and one of the O2? ions which is located on the mirror plane are not disordered. Each of the remaining O2? ions is split between two sites, with relative occupancies of 0.52:0.48 (O2? ions in general positions) and 0.64:0.36 (O2? ion on the mirror plane).
SBN60, strontium-barium niobate at 100?K
Marcin Stachowicz,a,* Olga Gawryszewska,a Marek A. Swirkowicz,b and Tadeusz Lukasiewicz
2013 Oct 1;
Data on disparities in mortality within low and middle income countries are limited, with little published data from the Caribbean or Central America. Our aim was to investigate disparities in overall and cause specific premature adult mortality in the multi-ethnic middle income country of Belize.
Mortality data from Belize 2008-2010 classified using the International Classification of Diseases 10 and the 2010 census stratified by age and ethnicity were used to calculate age, sex, and ethnic specific mortality rates for those 15-59 years, and life table analysis was used to estimate the probability of death between the ages of 15 and 59 (45q15).
The probability of death among those aged 15 to 59 years was 18.1% (women 13.5%, men 22.7%). Creole and Garifuna ethnic groups have three times the 45q15 probability of death compared to Mayan and Mestizo groups (Creole 31.2%, Garifuna 31.1%, Mayan 10.2%, Mestizo 12.0%). This pattern of ethnic disparity existed in both sexes but was greater in men. The probability of death from injuries was 14.8% among Creole men, more than twice the rate of other ethnicities and peaks among young Creole men. These deaths are dominated by homicides and unspecified deaths involving firearms
Marked disparities in mortality between ethnic groups exist in this Central American/Caribbean country, from rates that are typical of high-income countries to those of low-income countries. The pattern of these extreme differences likely suggests that they reflect underlying social determinants rooted in the country’s colonial past.
Ethnic and Gender Disparities in Premature Adult Mortality in Belize 2008-2010
Francis Morey,#1 Ian R. Hambleton,2 Nigel Unwin,3,¤ and T. Alafia Samuels#2,*