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Maltohexaose

$143

  • Brand : BIOFRON

  • Catalogue Number : BF-M2003

  • Specification : 98%

  • CAS number : 34620-77-4

  • Formula : C36H62O31

  • Molecular Weight : 990.86

  • PUBCHEM ID : 439606

  • Volume : 20mg

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Catalogue Number

BF-M2003

Analysis Method

HPLC,NMR,MS

Specification

98%

Storage

-20℃

Molecular Weight

990.86

Appearance

White crystalline powder

Botanical Source

honey

Structure Type

Carbohydrates

Category

Standards;Natural Pytochemical;API

SMILES

C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)OC4C(OC(C(C4O)O)OC5C(OC(C(C5O)O)OC6C(OC(C(C6O)O)O)CO)CO)CO)CO)CO)O)O)O)O

Synonyms

Maltohexaose,tech./malto-hexaose/Glc6/maltohexanose,dp6/AMYLOHEXAOSE/MALTOHEXAOSE/Maltohexose

IUPAC Name

(2R,3R,4S,5S,6R)-2-[(2R,3S,4R,5R,6R)-6-[(2R,3S,4R,5R,6R)-6-[(2R,3S,4R,5R,6R)-6-[(2R,3S,4R,5R,6R)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2R,3S,4R,5R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol

Density

1.87g/cm3

Solubility

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

Flash Point

744.7ºC

Boiling Point

1307.8ºC at 760mmHg

Melting Point

204-206°C

InChl

InChI=1S/C36H62O31/c37-1-7-13(43)14(44)21(51)32(58-7)64-27-9(3-39)60-34(23(53)16(27)46)66-29-11(5-41)62-36(25(55)18(29)48)67-30-12(6-42)61-35(24(54)19(30)49)65-28-10(4-40)59-33(22(52)17(28)47)63-26-8(2-38)57-31(56)20(50)15(26)45/h7-56H,1-6H2/t7-,8-,9-,10-,11-,12-,13-,14+,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31?,32-,33-,34-,35-,36-/m1/s1

InChl Key

OCIBBXPLUVYKCH-LIGGPISVSA-N

WGK Germany

RID/ADR

HS Code Reference

2940000000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:34620-77-4) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

PMID

31896254

Abstract

Maltooligosaccharide-forming amylases (MFAses) are promising tools for a variety of food industry applications because they convert starch into functional maltooligosaccharides. The MFAse from Bacillus stearothermophilus STB04 (BstMFAse) is a thermostable enzyme that preferentially produces maltopentaose and maltohexaose. An X-ray crystal structure of the BstMFAse-acarbose complex suggested that mutation of glycine 109 would increase its maltohexaose specificity. Using site-directed mutagenesis, glycine 109 was replaced with several different amino acids. Mutant-containing asparagine (G109N), aspartic acid (G109D), and phenylalanine (G109F) produced 36.1, 42.4, and 39.0% maltohexaose from starch, respectively, which was greater than that produced by the wild-type (32.9%). These mutants also exhibited substantially altered oligosaccharide hydrolysis patterns in favor of maltohexaose production. Homology models suggested that the mutants form extra interactions with the substrate at subsite -6, which were responsible for the enhanced maltohexaose specificity of BstMFAse. The results of this study support the proposition that binding of the substrate’s nonreducing end in the nonreducing end-subsite of the MFAse active center plays a crucial role in its product specificity.

KEYWORDS

crystal structure; maltohexaose; maltooligosaccharide-forming amylase; oligosaccharide hydrolysis pattern; product specificity

Title

Structure-Based Engineering of a Maltooligosaccharide-Forming Amylase To Enhance Product Specificity.

Author

Xie X1, Ban X1, Gu Z2,1,3, Li C2,1,3, Hong Y2,1,3, Cheng L2,1,3, Li Z2,1,3.

Publish date

2020 Jan 22

PMID

30620010

Abstract

Small molecule accumulation in Gram-negative bacteria is a key challenge to discover novel antibiotics, because of their two membranes and efflux pumps expelling toxic molecules. An approach to overcome this challenge is to hijack uptake pathways so that bacterial transporters shuttle the antibiotic to the cytoplasm. Here, we have characterized maltodextrin-fluorophore conjugates that can pass through both the outer and inner membranes mediated by components of the Escherichia coli maltose regulon. Single-channel electrophysiology recording demonstrated that the compounds permeate across the LamB channel leading to accumulation in the periplasm. We have also demonstrated that a maltotriose conjugate distributes into both the periplasm and cytoplasm. In the cytoplasm, the molecule activates the maltose regulon and triggers the expression of maltose binding protein in the periplasmic space indicating that the complete maltose entry pathway is induced. This maltotriose conjugate can (i) reach the periplasmic and cytoplasmic compartments to significant internal concentrations and (ii) auto-induce its own entry pathway via the activation of the maltose regulon, representing an interesting prototype to deliver molecules to the cytoplasm of Gram-negative bacteria.

Title

Mechanistic aspects of maltotriose-conjugate translocation to the Gram-negative bacteria cytoplasm.

Author

Dumont E1, Vergalli J1, Pajovic J2,3, Bhamidimarri SP4, Morante K4, Wang J4, Lubriks D5, Suna E5, Stavenger RA6, Winterhalter M4, Refregiers M2, Pages JM1.

Publish date

2018 Dec 28

PMID

29680348

KEYWORDS

cardiac implantable electronic devices; fluorescent imaging; infection; optical imaging

Title

Targeted Bacteria-Specific 18F-Fluoro-Maltohexaose But Not FDG PET Distinguishes Infection From Inflammation.

Author

Sajadi MM1, Chen W2, Dilsizian V2.

Publish date

2019 May;


Description :

Maltohexaose is a natural saccharide, and can be produced from amylose, amylopectin and whole starch.