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Methyl hexadecanoate

$52

  • Brand : BIOFRON

  • Catalogue Number : BD-P0681

  • Specification : 98.0%(GC)

  • CAS number : 112-39-0

  • Formula : C17H34O2

  • Molecular Weight : C17H34O2

  • Volume : 25mg

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Catalogue Number

BD-P0681

Analysis Method

Specification

98.0%(GC)

Storage

-20℃

Molecular Weight

C17H34O2

Appearance

Botanical Source

Structure Type

Aliphatic Compounds

Category

SMILES

CCCCCCCCCCCCCCCC(=O)OC

Synonyms

Uniphat A60/Methylhexadecanoate/n-Hexadecanoic acid methyl ester/Metholene 2216/Methyl Hexadecanoate/palmetic acid methyl ester/palmitic acid methyl ester/Palmitic acid, methyl ester (8CI)/Methyl palmitate/Hexadecanoic acid,methyl ester/Hexadecanoic acid, methyl ester/Methyl n-hexadecanoate

IUPAC Name

Applications

Density

0.9±0.1 g/cm3

Solubility

Methanol; Chloroform

Flash Point

152.8±7.5 °C

Boiling Point

332.1±0.0 °C at 760 mmHg

Melting Point

32-35 °C(lit.)

InChl

InChl Key

WGK Germany

RID/ADR

HS Code Reference

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:112-39-0) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

30579258

Abstract

BACKGROUND AND AIMS:
The lack of valid therapeutic approach that can ameliorate the manifestations of NASH is a barrier to therapeutic development. Therefore, we investigate the novel role of Methyl Palmitate (MP) in preventing NASH and the possible mechanism involved.

METHODS:
50 Male C57BL/6 J mice were randomly divided into 5 groups (n = 10). The control group was fed control diet; model group was fed MCD diet; MP 1 group was fed MCD diet supplemented with MP (75 mg/kg/day); MP 2 group was fed MCD plus MP diet (150 mg/kg/day); and MP 3 group was fed MCD plus MP diet (300 mg/kg/day). Histological staining’s, and commercially available kits for serum ALT and AST and hepatic contents of TG, TC, MDA, SOD, and GSH were used to assess NASH. Furthermore, relative liver protein and gene expression levels were determined by Western Blot and qPCR, respectively.

RESULTS:
Mice fed MCD diet developed NASH, which was markedly improved by MP in a dose-dependent manner. MP treatment improved hepatic content of TG, TC, MDA, SOD and GSH and serum levels of ALT and AST. In vivo studies showed that MP treatment activated PPARα expression, that in turns, promoted β-oxidation protein and gene expressions, suppressed TNFα, MCP1, TGFβ1 and Colla1 protein and gene expression levels, contributing to the prevention of NASH.

CONCLUSIONS:
Our results indicated that MP could successfully prevent NASH. This effect of MP was mediated through induction of PPARα pathway. This study provides a novel therapeutic target that plays pivotal role in the prevention of NASH.

Copyright © 2018 The Authors. Published by Elsevier Masson SAS.. All rights reserved.

KEYWORDS

Inflammation; MCD diet; Methyl palmitate; Non-alcoholic steatohepatitis; PPARα

Title

Administration of methyl palmitate prevents non-alcoholic steatohepatitis (NASH) by induction of PPAR-α.

Author

Zhang L1, Li HX1, Pan WS1, Ullah Khan F2, Qian C3, Qi-Li FR1, Xu X4.

Publish date

2019 Mar

PMID

29424632

Abstract

The production of biofuel using thermostable bacterial lipase from hot spring bacteria out of low-cost agricultural residue olive oil cake is reported in the present paper. Using a lipase enzyme from Bacillus licheniformis, a 66.5% yield of methyl esters was obtained. Optimum parameters were determined, with maximum production of lipase at a pH of 8.2, temperature 50.8°C, moisture content of 55.7%, and biosurfactant content of 1.693 mg. The contour plots and 3D surface responses depict the significant interaction of pH and moisture content with biosurfactant during lipase production. Chromatographic analysis of the lipase transesterification product was methyl esters, from kitchen waste oil under optimized conditions, generated methyl palmitate, methyl stearate, methyl oleate, and methyl linoleate.

KEYWORDS

Bacillus licheniformis; lipase; oil cake industry waste; response surface methodology; solid state fermentation

Title

Statistical optimization for lipase production from solid waste of vegetable oil industry.

Author

Sahoo RK1, Kumar M2, Mohanty S3, Sawyer M4, Rahman PKSM4, Sukla LB5, Subudhi E1.

Publish date

2018 Apr 21

PMID

29424632

Abstract

The production of biofuel using thermostable bacterial lipase from hot spring bacteria out of low-cost agricultural residue olive oil cake is reported in the present paper. Using a lipase enzyme from Bacillus licheniformis, a 66.5% yield of methyl esters was obtained. Optimum parameters were determined, with maximum production of lipase at a pH of 8.2, temperature 50.8°C, moisture content of 55.7%, and biosurfactant content of 1.693 mg. The contour plots and 3D surface responses depict the significant interaction of pH and moisture content with biosurfactant during lipase production. Chromatographic analysis of the lipase transesterification product was methyl esters, from kitchen waste oil under optimized conditions, generated methyl palmitate, methyl stearate, methyl oleate, and methyl linoleate.

KEYWORDS

Bacillus licheniformis; lipase; oil cake industry waste; response surface methodology; solid state fermentation

Title

Statistical optimization for lipase production from solid waste of vegetable oil industry.

Author

Sahoo RK1, Kumar M2, Mohanty S3, Sawyer M4, Rahman PKSM4, Sukla LB5, Subudhi E1.

Publish date

2018 Apr 21;