Catalogue Number
BN-O0970
Analysis Method
HPLC,NMR,MS
Specification
98%(HPLC)
Storage
2-8°C
Molecular Weight
538.46
Appearance
Botanical Source
Structure Type
Category
Standards;Natural Pytochemical;API
SMILES
C1=CC(=CC=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)OC4=C(C=CC(=C4)C5=CC(=O)C6=C(C=C(C=C6O5)O)O)O
Synonyms
2-{4-[5-(5,7-Dihydroxy-4-oxo-4H-chromen-2-yl)-2-hydroxyphenoxy]phenyl}-5,7-dihydroxy-4H-chromen-4-one/4H-1-Benzopyran-4-one, 2-[4-[5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-hydroxyphenoxy]phenyl]-5,7-dihydroxy-/4H-1-Benzopyran-4-one, 2-(4-(5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-hydroxyphenoxy)phenyl)-5,7-dihydroxy-/Ochinaflavone/Ochnaflavone/2,3-dihydroochnaflavone
IUPAC Name
2-[4-[5-(5,7-dihydroxy-4-oxochromen-2-yl)-2-hydroxyphenoxy]phenyl]-5,7-dihydroxychromen-4-one
Density
1.6±0.1 g/cm3
Solubility
Flash Point
281.5±27.8 °C
Boiling Point
832.1±65.0 °C at 760 mmHg
Melting Point
InChl
InChl Key
WGK Germany
RID/ADR
HS Code Reference
2933990000
Personal Projective Equipment
Correct Usage
For Reference Standard and R&D, Not for Human Use Directly.
Meta Tag
provides coniferyl ferulate(CAS#:50276-96-5) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate
No Technical Documents Available For This Product.
28695668
The study of the MeOH extract of the leaves of Campylospermum excavatum led to the isolation of a nitrile glucoside, named campyloside C (1) and an original derivative of ochnaflavone, 7-O-methylochnaflavone (2), along with three known biflavonoids, amentoflavone, sequoiaflavone, and sotetsuflavone (3 – 5). The linkage site of the sub-units of 2 was confirmed by chemical correlation, after semi-synthesis of a trimethoxylated derivative of ochnaflavone (2a). The structures of these compounds as well as their relative and absolute configurations were assigned by 1D- and 2D-NMR experiments, HR-ESI-MS and Electronic Circular Dichroism (ECD) calculations. A low-pass J filter HMBC experiment was performed in order to define the configuration of the double bond of 1. All of the biflavonoids were evaluated against protozoan parasites. Amentoflavone moderately inhibited the promastigote form of Leishmania infantum.
Campylospermum excavatum; Antiprotozoal agents; Biflavones; Nitrile glucoside; Ochnaceae.
A Nitrile Glucoside and Biflavones From the Leaves of Campylospermum Excavatum (Ochnaceae)
Gaetan Bayiha Ba Njock 1, Raphaël Grougnet 2, Antonia Efstathiou 3, Despina Smirlis 3, Gregory Genta-Jouve 4, Sylvie Michel 2, Josephine Ngo Mbing 1, Marina Kritsanida 2
2017 Nov
28032512
Anti-proliferative activity of the ethyl acetate fractions of Ochna schweinfurthiana F. Hoffm. and Ochna kibbiensis Hutch. and Dalziel methanol leaf extracts were investigated against glioblastoma multiforme (GBM U-1242 MG) cell line. O. kibbiensis significantly (p < 0.001) and dose dependently (IC50 = 25.74 μg/mL) reduced cell count. At 125 μg/mL, O. kibbiensis extract reduced cell count by about 92% compared to the untreated control. On the other hand, at 125 μg/mL, O. schweinfurthiana extract reduced cell count only by 20%, indicating a much weaker activity (IC50 = 823.51 μg/mL). Following from the result obtained, ethyl acetate fraction of O. kibbiensis was subjected to chromatographic purification. This led to the isolation of ochnaflavone; the structure of the isolated compound was identified by analysis of its nuclear magnetic resonance (NMR) spectral data and comparison with data in the literature. Although the isolated ochnaflavone could not be tested for anti-proliferative activity due to insufficient quantity, the obtained results indicate the presence of bioactive anti-GBM principles in O. kibbiensis.
Antiproliferative; O. kibbiensis; Ochna schweinfurthiana; glioblastoma multiforme; ochnaflavone.
Anti-proliferative Study and Isolation of Ochnaflavone From the Ethyl Acetate-Soluble Fraction of Ochna Kibbiensis Hutch & Dalziel
Abdullahi M Ismail 1, Aliyu M Musa 2, Tajuddeen Nasir 3, Mohammed G Magaji 4, Yusuf A Jega 1, Iliya Ibrahim 5
2017 Sep;
29144174
Triclisinone (2), a new ochnaflavone derivative, was isolated from the aerial parts of Triclisia gilletii, along with known drypemolundein B (1) and eight other known compounds. The chemical shifts of drypemolundein B (1) have been partially revised based on reinterpretation of NMR spectroscopic data. The eight other secondary metabolites are composed of: (+)-nonacosan-10-ol (3); stigmasterol (4), 3-O-β-D-glucopyranosylsitosterol (5), 3-O-β-D-glucopyranosylstigmasterol (6); oleanic acid (7); myricetin (8), quercetin (9) and 3-methoxyquercetin (10). Their structures were elucidated using IR, MS, NMR 1D and 2D, 1H and 13C and comparison with literature data. Furthermore, compounds 1, 2, 5, 6, 8, 9 and the crude extract were tested against Mycobacterium tuberculosis. Compounds 1, 2, 8 and 9 displayed moderate to very good activity against resistant strain (codified AC 45) of M. tuberculosis with minimum inhibitory concentrations MICs ranging from 3.90 to 62.5 μg/mL.
Menispermaceae; NMR chemical shift analysis; antimycobacterial activity; ochnaflavone derivative.
Secondary Metabolites From Triclisia Gilletii (De Wild) Staner (Menispermaceae) With Antimycobacterial Activity Against Mycobacterium Tuberculosis
Eric Robert Tiam 1, Dominique Serge Ngono Bikobo 1 2, Auguste Abouem A Zintchem 1 3, Norbert Mbabi Nyemeck 2nd 1 4, Esther Del Florence Moni Ndedi 5, Patrick Herve Betote Diboue 5, Maximilienne Ascension Nyegue 5, Alex de Theodore Atchade 1, Dieudonne Emmanuel Pegnyemb 1, Christian G Bochet 2, Ulrich Koert 4
2019 Mar;
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