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Odonicin

$1,216

  • Brand : BIOFRON

  • Catalogue Number : BN-O1490

  • Specification : 98%(HPLC)

  • CAS number : 51419-51-3

  • Formula : C24H30O7

  • Molecular Weight : 430.5

  • PUBCHEM ID : 14106499

  • Volume : 5mg

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Catalogue Number

BN-O1490

Analysis Method

HPLC,NMR,MS

Specification

98%(HPLC)

Storage

-20℃

Molecular Weight

430.5

Appearance

Cryst.

Botanical Source

This product is isolated and purified from the herbs of Rabdosia longituba

Structure Type

Diterpenoids

Category

Standards;Natural Pytochemical;API

SMILES

CC(=O)OC1C2C(C=CC(=O)C23COC1(C45C3CCC(C4)C(=C)C5OC(=O)C)O)(C)C

Synonyms

(5β,6β,7α,8α,9β,10α,13α,15α)-7-Hydroxy-1-oxo-7,20-epoxykaura-2,16-diene-6,15-diyl diacetate/(5β,6β,8α,9β,10α,13α)-7-Hydroxy-1-oxo-7,20-epoxykaura-2,16-diene-6,15-diyl diacetate/Odonicin

IUPAC Name

[(1S,2S,5R,7R,8S,9S,10S,11R)-7-acetyloxy-9-hydroxy-12,12-dimethyl-6-methylidene-15-oxo-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadec-13-en-10-yl] acetate

Density

1.3±0.1 g/cm3

Solubility

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

Flash Point

182.8±23.6 °C

Boiling Point

545.7±50.0 °C at 760 mmHg

Melting Point

InChl

InChI=1S/C24H30O7/c1-12-15-6-7-16-22-11-29-24(28,23(16,10-15)19(12)30-13(2)25)20(31-14(3)26)18(22)21(4,5)9-8-17(22)27/h8-9,15-16,18-20,28H,1,6-7,10-11H2,2-5H3/t15-,16+,18-,19-,20+,22-,23+,24-/m1/s1

InChl Key

VIZWMBLJPXPZSQ-CMJIRCKQSA-N

WGK Germany

RID/ADR

HS Code Reference

2933990000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:51419-51-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

26078326

Abstract

This study aims to explore and characterize the malaria-endemic situation and trends from 2004 to 2013, to provide useful evidence for subsequently more effective strategic planning of malaria elimination in China. A total of 256,179 confirmed malaria cases were recorded in this period, and 86.8% of them were reported during 2004-2008. Between 2004 and 2008, Plasmodium vivax was the major species (72.2%) of malaria parasite. Most cases (67.3%) were found in male, and mainly in the age group of 35-39 years. A total of 236 deaths resulting from malaria were reported and nearly half (45.3%) of them were in Yunnan province. In all, 204,760 local malaria (79.9%) and 51,419 imported malaria (20.1%) were observed during 2004-2013. However, afterward the proportion of imported malaria continuously increased from 2004 (16.2%) to 2013 (97.9%). Moreover, 9,285 imported malaria cases were recorded during 2011-2013 in China, of which 5,976 cases (64.4%) came back from Africa. Overall, China has made achievements in controlling malaria, the locally transmitted malaria significantly declined in the past decades, by which the incidence has achieved historically the lowest levels. On the other hand, imported malaria has increasingly become a severe threat to malaria elimination. Therefore, to prevent the reintroduction of malaria, surveillance systems need to be well planned and managed to ensure timely case detection and prompt response at the elimination stage.

Title

Analysis of Malaria Epidemiological Characteristics in the People's Republic of China, 2004-2013

Author

Jun Feng, Huihui Xiao, Zhigui Xia, Li Zhang, Ning Xiao

Publish date

2015 Aug 5

PMID

26309130

Abstract

Both bacterial symbionts and pathogens rely on their host-sensing mechanisms to activate the biosynthetic pathways necessary for their invasion into host cells. The Gram-negative bacterium Sinorhizobium meliloti relies on its RSI (ExoR-ExoS-ChvI) Invasion Switch to turn on the production of succinoglycan, an exopolysaccharide required for its host invasion. Recent whole-genome sequencing efforts have uncovered putative components of RSI-like invasion switches in many other symbiotic and pathogenic bacteria. To explore the possibility of the existence of a common invasion switch, we have conducted a phylogenomic survey of orthologous ExoR, ExoS, and ChvI tripartite sets in more than ninety proteobacterial genomes. Our analyses suggest that functional orthologs of the RSI invasion switch co-exist in Rhizobiales, an order characterized by numerous invasive species, but not in the order’s close relatives. Phylogenomic analyses and reconstruction of orthologous sets of the three proteins in Alphaproteobacteria confirm Rhizobiales-specific gene synteny and congruent RSI evolutionary histories. Evolutionary analyses further revealed site-specific substitutions correlated specifically to either animal-bacteria or plant-bacteria associations. Lineage restricted conservation of any one specialized gene is in itself an indication of species adaptation. However, the orthologous phylogenetic co-occurrence of all interacting partners within this single signaling pathway strongly suggests that the development of the RSI switch was a key adaptive mechanism. The RSI invasion switch, originally found in S. meliloti, is a characteristic of the Rhizobiales, and potentially a conserved crucial activation step that may be targeted to control host invasion by pathogenic bacterial species.

Title

Phylogenetic Co-Occurrence of ExoR, ExoS, and ChvI, Components of the RSI Bacterial Invasion Switch, Suggests a Key Adaptive Mechanism Regulating the Transition between Free-Living and Host-Invading Phases in Rhizobiales

Author

Mary Ellen Heavner, Wei-Gang Qiu, Hai-Ping Cheng

Publish date

2015

PMID

24244590

Abstract

Tree peonies are important ornamental plants worldwide, but growing them can be frustrating due to their short and concentrated flowering period. Certain cultivars exhibit a reblooming trait that provides a valuable alternative for extending the flowering period. However, the genetic control of reblooming in tree peonies is not well understood. In this study, we compared the molecular properties and morphology of reblooming and non-reblooming tree peonies during the floral initiation and developmental processes. Using transcriptome sequencing technology, we generated 59,275 and 63,962 unigenes with a mean size of 698 bp and 699 bp from the two types of tree peonies, respectively, and identified eight differentially expressed genes that are involved in the floral pathways of Arabidopsis thaliana. These differentially regulated genes were verified through a detailed analysis of their expression pattern during the floral process by real time RT-PCR. From this combined analysis, we identified four genes, PsFT, PsVIN3, PsCO and PsGA20OX, which likely play important roles in the regulation of the reblooming process in tree peonies. These data constitute a valuable resource for the discovery of genes involved in flowering time and insights into the molecular mechanism of flowering to further accelerate the breeding of tree peonies and other perennial woody plants.

Title

Transcriptome Comparison Reveals Key Candidate Genes Responsible for the Unusual Reblooming Trait in Tree Peonies

Author

Hua Zhou, Fang-Yun Cheng, Rong Wang, Yuan Zhong, Chaoying He

Publish date

2013;


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