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Orcinolglucoside

$113

  • Brand : BIOFRON

  • Catalogue Number : BF-O2005

  • Specification : 98%

  • CAS number : 21082-33-7

  • Formula : C13H18O7

  • Molecular Weight : 286.28

  • PUBCHEM ID : 70700401

  • Volume : 20mg

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Catalogue Number

BF-O2005

Analysis Method

HPLC,NMR,MS

Specification

98%

Storage

-20℃

Molecular Weight

286.28

Appearance

Light Yellow crystalline powder

Botanical Source

Ophiopogon japonicus,Curculigo orchioides,Rumex nepalensis

Structure Type

Phenolics

Category

Standards;Natural Pytochemical;API

SMILES

CC1=CC(=CC(=C1)OC2C(C(C(C(O2)CO)O)O)O)O

Synonyms

Orcinol glucoside/3-Hydroxy-5-methylphenyl D-glucopyranoside/D-Glucopyranoside, 3-hydroxy-5-methylphenyl

IUPAC Name

(2R,3S,4S,5R)-2-(hydroxymethyl)-6-(3-hydroxy-5-methylphenoxy)oxane-3,4,5-triol

Density

1.5±0.1 g/cm3

Solubility

Methanol; Water

Flash Point

298.9±30.1 °C

Boiling Point

570.6±50.0 °C at 760 mmHg

Melting Point

InChl

InChI=1S/C13H18O7/c1-6-2-7(15)4-8(3-6)19-13-12(18)11(17)10(16)9(5-14)20-13/h2-4,9-18H,5H2,1H3/t9-,10-,11+,12-,13?/m1/s1

InChl Key

YTXIGTCAQNODGD-HENWMNBSSA-N

WGK Germany

RID/ADR

HS Code Reference

2938900000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:21082-33-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Article Available.


Description :

Orcinol glucoside produces antidepressant effects by blocking the behavioural and neuronal deficits caused by chronic stress PUMID/DOI:23838013 Eur Neuropsychopharmacol.?2014 Jan;24(1):172-80. This study focused on the antidepressant potential of orcinol glucoside ((Sakakin, OG) and its possible mechanisms of action. We established a depressed rat model using 3 consecutive weeks of chronic unpredictable mild stress (CUMS). The antidepressant-like effect of OG was revealed using the sucrose preference test, the open field test, the forced swimming test (FST), and the tail suspension test (TST). The results showed that OG treatment (1.5, 3, or 6mg/kg) alleviated the depression-like behaviour of rats under CUMS, as indicated by the increased sucrose preference and the decreased immobility in both the FST and TST, although the rearing frequency in the open field test increased only in the group that received the lowest dose (1.5mg/kg OG). Rats that received OG treatment exhibited reduced serum CORT levels and CRH mRNA expression in the hypothalamus, suggesting that the hyperactivity of the HPA axis in CUMS rats was reversed by OG treatment. Antioxidative phenols and phenolic glycosides from Curculigo orchioides PUMID/DOI:16079552 Chem Pharm Bull (Tokyo). 2005 Aug;53(8):1065-7. A new orcinol glucoside, orcinol-1-O-beta-D-apiofuranosyl-(1-->6)-beta-D-glucopyranoside (3), was isolated from the rhizomes of Curculigo orchioides GAERTN., together with seven known compounds: orcinol glucoside (Sakakin,1), orcinol-1-O-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranoside (2), curculigoside (4), curculigoside B (5), curculigoside C (6), 2,6-dimethoxyl benzoic acid (7), and syringic acid (8). The structures of these compounds were elucidated using spectroscopic methods. The antioxidant activities of these isolated compounds were evaluated by colorimetric methods based on their scavenging effects on hydroxyl radicals and superoxide anion radicals, respectively. All the compounds showed potent antioxidative activities and the structure-activity relationship is discussed.