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Pentoxyverine citrate

$87

  • Brand : BIOFRON

  • Catalogue Number : BN-O1206

  • Specification : 98%(HPLC)

  • CAS number : 23142-01-0

  • Formula : C26H39NO10

  • Molecular Weight : 525.6

  • PUBCHEM ID : 90010

  • Volume : 5mg

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Catalogue Number

BN-O1206

Analysis Method

Specification

98%(HPLC)

Storage

2-8°C

Molecular Weight

525.6

Appearance

Botanical Source

Structure Type

Category

SMILES

CCN(CC)CCOCCOC(=O)C1(CCCC1)C2=CC=CC=C2.C(C(=O)O)C(CC(=O)O)(C(=O)O)O

Synonyms

Takabetan/PENCAL/carbetapentonecitrate/Pentoxyverine Citrate/Cyclopentanecarboxylic acid,1-phenyl-,2-[2-(diethylamino)ethoxy]ethyl ester/Astomatop/PENTOXIVERINE CITRATE/loucarbate/2-[2-(Diethylamino)ethoxy]ethyl 1-phenylcyclopentanecarboxylate 2-hydroxy-1,2,3-propanetricarboxylate (1:1)/2-[2-(Diethylamino)ethoxy]ethyl 1-phenylcyclopentanecarboxylate 2-hydroxypropane-1,2,3-tricarboxylate (1:1)/Carbetapentan-citrat/toclase/Gai-Less/1-Phenylcyclopentanecarboxylic Acid 2-(2-(Diethylamino)ethoxy)ethyl Ester Citrate (1:1)/Cyclopentanecarboxylic acid, 1-phenyl-, 2-[2-(diethylamino)ethoxy]ethyl ester, 2-hydroxy-1,2,3-propanetricarboxylate (1:1) (salt)/CARETAPENTANE CITRATE/Carbetapentane citrate salt/1-Phenylcyclopentanecarboxylic acid 2-(2-diethylaminoethoxy)ethyl ester citrate salt/Atomin S/2-(2-diethylaminoethoxy)ethyl 1-phenylcyclopentane-1-carboxylate; 2-hydroxypropane-1,2,3-tricarboxylic acid/Fustpentane/Calnathal/Carbetapentane (citrate)

IUPAC Name

2-[2-(diethylamino)ethoxy]ethyl 1-phenylcyclopentane-1-carboxylate;2-hydroxypropane-1,2,3-tricarboxylic acid

Density

Solubility

Flash Point

217.2ºC

Boiling Point

435.5ºC at 760mmHg

Melting Point

84-86?C

InChl

InChl Key

AKJDEXBCRLOVTH-UHFFFAOYSA-N

WGK Germany

RID/ADR

HS Code Reference

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:23142-01-0) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

26976742

Abstract

Leishmania and Trypanosoma are unicellular parasites that possess markedly original biological features as compared to other eukaryotes. The Leishmania genome displays a constitutive ‘mosaic aneuploidy’, whereas in Trypanosoma brucei, the megabase-sized chromosomes are diploid. We accurately analysed DNA replication parameters in three Leishmania species and Trypanosoma brucei as well as mouse embryonic fibroblasts (MEF). Active replication origins were visualized at the single molecule level using DNA molecular combing. More than one active origin was found on most DNA fibres, showing that the chromosomes are replicated from multiple origins. Inter-origin distances (IODs) were measured and found very large in trypanosomatids: the mean IOD was 160 kb in T. brucei and 226 kb in L. mexicana. Moreover, the progression of replication forks was faster than in any other eukaryote analyzed so far (mean velocity 1.9 kb/min in T. brucei and 2.4-2.6 kb/min in Leishmania). The estimated total number of active DNA replication origins in trypanosomatids is ~170. Finally, 14.4% of unidirectional replication forks were observed in T. brucei, in contrast to 1.5-1.7% in Leishmania and 4% in MEF cells. The biological significance of these original features is discussed.

Title

Single-molecule analysis of DNA replication reveals novel features in the divergent eukaryotes Leishmania and Trypanosoma brucei versus mammalian cells

Author

Slavica Stanojcic,1 Lauriane Sollelis,1 Nada Kuk,1 Lucien Crobu,2 Yves Balard,1 Etienne Schwob,4 Patrick Bastien,1,2,3 Michel Pages,a,2 and Yvon Sterkersb,1,2,3

Publish date

2016;

PMID

16665819

Abstract

Specific wavelengths of light required for expression of phytotoxic activity of S-23142 (N-[4-chloro-2-fluoro-5-propargyloxy]phenyl-3,4,5,6-tetra- hydrophthalimide) and acifluorfen-ethyl (ethyl-5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitro benzoic acid) were determined in cotyledons of cucumber seedlings using the Okazaki Large Spectrograph. Leakage of amino acids from the cotyledons was measured as an indication of the phytotoxic activity. The wavelength effects showed common major peaks of activity at 550 and 650 nanometers and a minor peak at 450 nanometers for both herbicides, indicating a common primary photoreaction. Concomitant application of DCMU (3-[3,4-dichlorophenyl]-1,1-dimethylurea) with S-23142 had little influence on the effective wavelengths for S-23142 activity. Light of 450 and 650 nanometers was relatively less effective in achlorophyllous tissue grown in far red light than in green tissue. These results strongly suggest that the phytotoxic action of S-23142 and diphenylethers involves multiple photoreactions and that one of the photoreceptor pigments may be chlorophyll or its related pigment, although photosynthesis is not involved.

Title

Wavelength Effect on the Action of a N-Phenylimide S-23142 and a Diphenylether Acifluorfen-Ethyl in Cotyledons of Cucumber (Cucumis sativus L.) Seedlings 1

Author

Ryo Sato, Eiki Nagano, Hiromichi Oshio, Katsuzo Kamoshita, and Masaki Furuya2

Publish date

1987 Dec

PMID

30410583

Abstract

Background
Visceral adiposity indicators and the product of triglyceride and fasting plasma glucose (TyG) index-related parameters are effective surrogate markers for insulin resistance (IR) and are predictors of metabolic syndrome and diabetes mellitus. However, their genetic determinants have not been previously reported. Pleiotropic associations of LIPC variants have been observed in lipid profiles and atherosclerotic cardiovascular diseases. We aimed to investigate LIPC polymorphisms as the genetic determinants of adiposity status, visceral adiposity indicators and TyG index-related parameters.

Methods
A total of 592 participants from Taiwan were genotyped for three LIPC single nucleotide polymorphisms (SNPs).

Results
The LIPC SNPs rs2043085 and rs1532085 were significantly associated with body mass index (BMI), waist circumference (WC), lipid accumulation product, visceral adiposity index, and TyG index-related parameters [including the TyG index, TyG with adiposity status (TyG-BMI), and TyG-WC index], whereas the rs1800588 SNP was only significantly associated with the TyG index. The associations became nonsignificant after further adjustment for serum TG levels. No significant association was observed between any the studied LIPC SNPs and IR status.

Conclusion
Our data revealed a pleiotropic association between the LIPC variants and visceral adiposity indicators and TyG index-related parameters, which are mediated by serum TG levels.

Electronic supplementary material
The online version of this article (10.1186/s13098-018-0383-9) contains supplementary material, which is available to authorized users.

KEYWORDS

LIPC variants as genetic determinants of adiposity status, visceral adiposity indicators, and triglyceride-glucose (TyG) index-related parameters mediated by serum triglyceride levels

Title

LIPC variants as genetic determinants of adiposity status, visceral adiposity indicators, and triglyceride-glucose (TyG) index-related parameters mediated by serum triglyceride levels

Author

Ming-Sheng Teng,#1 Semon Wu,#1,2 Leay-Kiaw Er,3,4 Lung-An Hsu,5 Hsin-Hua Chou,6 and Yu-Lin Kocorresponding author1,4,6

Publish date

2018;


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