We Offer Worldwide Shipping
Login Wishlist

Pholidotol C

$1,152

  • Brand : BIOFRON

  • Catalogue Number : BN-O0957

  • Specification : 98%(HPLC)

  • CAS number : 1013909-91-5

  • Formula : C15H14O4

  • Molecular Weight : 258.27

  • Volume : 5mg

Available on backorder

Quantity
Checkout Bulk Order?

Catalogue Number

BN-O0957

Analysis Method

HPLC,NMR,MS

Specification

98%(HPLC)

Storage

2-8°C

Molecular Weight

258.27

Appearance

Solid

Botanical Source

Structure Type

Phenols

Category

Standards;Natural Pytochemical;API

SMILES

C1=CC=C2C(=C1)C3=CC=CC=C3N2C4=CC5=C(C=C4)N(C6=CC=CC=C65)C7=CC8=C(C=C7)OC9=C(C81C2=C(C3=C1C=C(C=N3)N1C3=CC=CC=C3C3=CC=CC=C31)N=CC(=C2)N1C2=CC=CC=C2C2=CC=CC=C21)C=C(C=C9)N1C2=CC=CC=C2C2=CC=CC=C21

Synonyms

2',5,11-tri(carbazol-9-yl)-7'-(3-carbazol-9-ylcarbazol-9-yl)spiro[3,13-diazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene-8,9'-xanthene]

IUPAC Name

Density

Solubility

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

Flash Point

Boiling Point

Melting Point

InChl

InChI=1S/C83H49N7O/c1-10-28-69-55(19-1)56-20-2-11-29-70(56)86(69)50-37-40-78-64(43-50)63-27-9-18-36-77(63)88(78)52-39-42-80-66(45-52)83(65-44-51(38-41-79(65)91-80)87-71-30-12-3-21-57(71)58-22-4-13-31-72(58)87)67-46-53(89-73-32-14-5-23-59(73)60-24-6-15-33-74(60)89)48-84-81(67)82-68(83)47-54(49-85-82)90-75-34-16-7-25-61(75)62-26-8-17-35-76(62)90/h1-49H

InChl Key

AMPVKSQOPJSHLK-UHFFFAOYSA-N

WGK Germany

RID/ADR

HS Code Reference

2933990000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:1013909-91-5) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

24990991

Abstract

Gene conversions and crossovers are related products of the repair of double-stranded DNA breaks by homologous recombination. Most previous studies of mitotic gene conversion events have been restricted to measuring conversion tracts that are <5 kb. Using a genetic assay in which the lengths of very long gene conversion tracts can be measured, we detected two types of conversions: those with a median size of ∼6 kb and those with a median size of >50 kb. The unusually long tracts are initiated at a naturally occurring recombination hotspot formed by two inverted Ty elements. We suggest that these long gene conversion events may be generated by a mechanism (break-induced replication or repair of a double-stranded DNA gap) different from the short conversion tracts that likely reflect heteroduplex formation followed by DNA mismatch repair. Both the short and long mitotic conversion tracts are considerably longer than those observed in meiosis. Since mitotic crossovers in a diploid can result in a heterozygous recessive deleterious mutation becoming homozygous, it has been suggested that the repair of DNA breaks by mitotic recombination involves gene conversion events that are unassociated with crossing over. In contrast to this prediction, we found that ∼40% of the conversion tracts are associated with crossovers. Spontaneous mitotic crossover events in yeast are frequent enough to be an important factor in genome evolution.

KEYWORDS

yeast, mitotic recombination, gene conversion, DNA damage repair, loss of heterozygosity

Title

High-Resolution Mapping of Two Types of Spontaneous Mitotic Gene Conversion Events in Saccharomyces cerevisiae

Author

Eunice Yim, Karen E. O’Connell, Jordan St. Charles,1 and Thomas D. Petes2

Publish date

2014 Sep;


Description :

Empty ...