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Piceatannol 3′-O-glucoside

$538

  • Brand : BIOFRON

  • Catalogue Number : BD-P0090

  • Specification : 98.0%(HPLC)

  • CAS number : 94356-26-0

  • Formula : C20H22O9

  • Molecular Weight : 406.4

  • PUBCHEM ID : 11968990

  • Volume : 25mg

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Quantity
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Catalogue Number

BD-P0090

Analysis Method

HPLC,NMR,MS

Specification

98.0%(HPLC)

Storage

2-8°C

Molecular Weight

406.4

Appearance

Powder

Botanical Source

Structure Type

Phenols

Category

SMILES

C1=CC(=C(C=C1C=CC2=CC(=CC(=C2)O)O)OC3C(C(C(C(O3)CO)O)O)O)O

Synonyms

(2S,3R,4S,5S,6R)-2-[5-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]-2-hydroxyphenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol

IUPAC Name

(2S,3R,4S,5S,6R)-2-[5-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]-2-hydroxyphenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol

Applications

Density

1.6±0.1 g/cm3

Solubility

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

Flash Point

390.2±32.9 °C

Boiling Point

721.6±60.0 °C at 760 mmHg

Melting Point

InChl

InChI=1S/C20H22O9/c21-9-16-17(25)18(26)19(27)20(29-16)28-15-7-10(3-4-14(15)24)1-2-11-5-12(22)8-13(23)6-11/h1-8,16-27H,9H2/b2-1+/t16-,17-,18+,19-,20-/m1/s1

InChl Key

UMGCIIXWEFTPOC-CUYWLFDKSA-N

WGK Germany

RID/ADR

HS Code Reference

2938900000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:94356-26-0) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

94356

Abstract

Sera from C3H mammary tumor-bearing mice contain cytotoxic antibodies for mouse mammary tumor virus (MMTV)-producing cells, based on 51Cr release in a complement-dependent serum cytotoxicity assay. The cytotoxic antibodies could be absorbed by purified C3H MMTV gp52 and C3H MMTV-infected cat cells (C3H [MMTV] CrFK) containing cell surface MMTV gp52. However, purified MMTV p27 and uninfected CrFK cat cells were negative. Absorption of the sera with GR (MMTV) CrFK cells also removed all of the cytotoxicity, whereas absorption with RIII (MMTV) CrFK cells was negative, even though all three infected cat cells contained equivalent amounts of gp52. The same C3H cytotoxic sera also neutralized the focus-forming capacity of a C3H MMTV pseudotype of Kirsten sarcoma virus containing MMTV gp52. In contrast, sera from mammary tumor-bearing GR and RIII mice did not neutralize the pseudotype. Furthermore, neutralization could be achieved only by anti-gp52 but not by anti-gp36, -p27, -p14, or -p10 C3H MMTV sera. The gp52’s of C3H, GR, and RIII MMTV could also be distinguished by using a type-specific competition radioimmunoassay employing 125I-gp52 of C3H MMTV and a hyperimmune rabbit anti-C3H MMTV serum. To demonstrate these differences directly, we studied the primary structure of gp52 on the surface of the C3H, GR, and RIII (MMTV) CrFK cells. Two-dimensional tryptic peptide maps of the cell surface lactoper-oxidase-catalyzed iodinated gp52’s revealed a greater number of peptides common to the gp52’s of C3H and GR MMTVs than to RIII MMTV gp52. These results demonstrate that gp52 is a major target antigen for both cytotoxic and neutralizing antibodies, that the cell surface and virion-associated gp52’s of C3H, GR, and RIII MMTV contain both group- and type-specific determinants, and that C3H and GR MMTV gp52’s are antigenically more related to each other than to RIII MMTV gp52. Furthermore, C3H mammary tumor-bearing mice develop type-specific antibodies capable of recognizing unique gp52 determinants and, therefore, are able to distinguish the gp52 of C3H MMTV from the gp52’s of GR and RIII MMTV.

Title

Mice with Spontaneous Mammary Tumors Develop Type-Specific Neutralizing and Cytotoxic Antibodies Against the Mouse Mammary Tumor Virus Envelope Protein gp52

Author

Gerald Schochetman, Larry O. Arthur, Cedric W. Long, and Richard J. Massey

Publish date

1979 Oct

PMID

30356598

Abstract

Purpose
The primary aim of this study was to develop an assessment of the fundamental, combined, and complex movement skills required to support childhood physical literacy. The secondary aim was to establish the feasibility, objectivity, and reliability evidence for the assessment.

Methods
An expert advisory group recommended a course format for the assessment that would require children to complete a series of dynamic movement skills. Criterion-referenced skill performance and completion time were the recommended forms of evaluation. Children, 8-12 years of age, self-reported their age and gender and then completed the study assessments while attending local schools or day camps. Face validity was previously established through a Delphi expert (n = 19, 21% female) review process. Convergent validity was evaluated by age and gender associations with assessment performance. Inter- and intra-rater (n = 53, 34% female) objectivity and test-retest (n = 60, 47% female) reliability were assessed through repeated test administration.

Results
Median total score was 21 of 28 points (range 5-28). Median completion time was 17 s. Total scores were feasible for all 995 children who self-reported age and gender. Total score did not differ between inside and outside environments (95% confidence interval (CI) of difference: −0.7 to 0.6; p = 0.91) or with/without footwear (95%CI of difference: −2.5 to 1.9; p = 0.77). Older age (p < 0.001, η2 = 0.15) and male gender (p < 0.001, η2 = 0.02) were associated with a higher total score. Inter-rater objectivity evidence was excellent (intraclass correlation coefficient (ICC) = 0.99) for completion time and substantial for skill score (ICC = 0.69) for 104 attempts by 53 children (34% female). Intra-rater objectivity was moderate (ICC = 0.52) for skill score and excellent for completion time (ICC = 0.99). Reliability was excellent for completion time over a short (2-4 days; ICC = 0.84) or long (8-14 days; ICC = 0.82) interval. Skill score reliability was moderate (ICC = 0.46) over a short interval, and substantial (ICC = 0.74) over a long interval. Conclusion The Canadian Agility and Movement Skill Assessment is a feasible measure of selected fundamental, complex and combined movement skills, which are an important building block for childhood physical literacy. Moderate-to-excellent objectivity was demonstrated for children 8-12 years of age. Test-retest reliability has been established over an interval of at least 1 week. The time and skill scores can be accurately estimated by 1 trained examiner.

KEYWORDS

Agility course, Children, Dynamic motor skill, Locomotor skill, Object manipulation, Population assessment

Title

Canadian Agility and Movement Skill Assessment (CAMSA): Validity, objectivity, and reliability evidence for children 8-12 years of age

Author

Patricia E. Longmuir,a,b,* Charles Boyer,a Meghann Lloyd,c Michael M. Borghese,a,d Emily Knight,a Travis J. Saunders,a,e Elena Boiarskaia,f Weimo Zhu,f and Mark S. Tremblaya,b

Publish date

2017 Jun;

PMID

30416932

Abstract

Purpose of review
Our goal was to assess current literature and knowledge on associations between characteristics (mean, variability, extremes) of ambient temperatures and human health. We were motivated by concerns that climate change, which operates on a time frame of decades or longer, may influence not only shorter-term associations between weather and health (daily/weekly) but also have enduring implications for population health. We reviewed papers published between 2010 and 2017 on the health effects of longer-term (3 weeks to years) exposures to ambient temperature. We sought to answer: ‘What health outcomes have been associated with longer-term exposures?’ We included studies on a diverse range of health outcomes, with the exception of vector borne diseases such as malaria. Longer-term exposures were considered to be exposures to annual and seasonal temperatures and temperature variability.

Recent findings
We found 26 papers meeting inclusion criteria, which addressed mortality, morbidity, respiratory disease, obesity, suicide, infectious diseases and allergies among various age groups. In general, most studies found associations between longer-term temperature metrics and health outcomes. Effects varied by population subgroup. For example, associations with suicide differed by sex and underlying chronic illness modified effects of heat on mortality among the elderly.

Summary
We found that regional and local temperatures, and changing conditions in weather due to climate change, were associated with a diversity of health outcomes through multiple mechanisms. Future research should focus on evidence for particular mechanistic pathways in order to inform adaptation responses to climate change.

KEYWORDS

temperature, review, epidemiology, climate change

Title

Longer-Term Outdoor Temperatures and Health Effects: A Review

Author

Antonella Zanobetti, PhD1 and Marie S. O’Neill, PhD2

Publish date

2019 Jun 1.