This product is isolated and purified from the bark of Phellodendron chinense
Pyruvicacid phenylhydrazone/2-Phenylhydrazono-propionsaeure/2-phenylhydrazono-propionic acid/Brenztraubensaeure-phenylhydrazon/piscidinol A/(13α,14β,17α,20S,23R,24S)-23,24,25-Trihydroxylanost-7-en-3-one/3-oxo-threo-23,24,25-trihydroxytirucall-7-ene/Lanost-7-en-3-one, 23,24,25-trihydroxy-, (13α,14β,17α,20S,23R,24S)-/piruvic acid phenylhydrazone/pyruvate phenylhydrazone
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
599.4±50.0 °C at 760 mmHg
HS Code Reference
Personal Projective Equipment
For Reference Standard and R&D, Not for Human Use Directly.
provides coniferyl ferulate(CAS#:100198-09-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate
Four types of piscidinol A derivatives were synthesized and evaluated their ability to inhibit HIV-1 protease to understand their structure-activity relationships. Of these tirucallane-type triterpene derivatives, an A-seco derivative (1b) moderately inhibited human immunodeficiency virus (HIV) protease (IC50 38.2 μM). The 2,2-dimethyl succinic acid (DMS) acylated tirucallane derivatives (4b, 6a, and 7b, 50 < IC50 < 100 μM) were more inhibitory against HIV-1 PR than the others (PA, 2a, 4a, 4c-4d, 5a, 6b-6d, and 7a, IC50 > 100 μM). These findings indicated that the 2,3-seco-2,3-dioic acid (1b) and DMS-acylated tirucallane-type derivatives preferably inhibited HIV viral protease.
A-ring modified derivatives; HIV-1 protease; bi-acylated derivatives; mono-acylated derivatives; multi-acylated derivatives; piscidinol A
Synthesis of piscidinol A derivatives and their ability to inhibit HIV-1 protease.
Wei Y1, Ma CM2, Jiang TB1, Du J1, Zhou X3, Liu GQ1, Hattori M4.