Catalogue Number
BD-P0008
Analysis Method
Specification
94.0%(HPLC)
Storage
-20℃
Molecular Weight
522.46
Appearance
Yellow powder
Botanical Source
This product is isolated and purified from the herbs of Hypericum perforatum L.
Structure Type
Category
SMILES
CC1=CC(=C2C(=C1)C3=C4C5=CC(=CC(=C5C(=O)C6=C(C=C(C(=C46)C7=C3C(=C(C=C7O)O)C2=O)O)O)O)CO)O
Synonyms
IUPAC Name
Density
1.8±0.1 g/cm3
Solubility
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Flash Point
584.0±30.8 °C
Boiling Point
1019.3±65.0 °C at 760 mmHg
Melting Point
InChl
InChl Key
QFAPJWSQKUFHAP-UHFFFAOYSA-N
WGK Germany
RID/ADR
HS Code Reference
Personal Projective Equipment
Correct Usage
For Reference Standard and R&D, Not for Human Use Directly.
Meta Tag
provides coniferyl ferulate(CAS#:54328-09-5) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate
No Technical Documents Available For This Product.
26822391
Plants of the genus Hypericum are widely known for their therapeutic properties. The most biologically active compounds of this genus are naphtodianthrones and phloroglucinols. Indirect desorption electrospray ionization mass spectrometry (DESI-MS) imaging allows visualization and localization of secondary metabolites in different plant tissues. This study is focused on localization of major secondary compounds in the leaves of 17 different in vitro cultured Hypericum species classified in 11 sections. Generally, all identified naphtodianthrones, protohypericin, hypericin, protopseudohypericin and pseudohypericin were co-localized in the dark glands of eight hypericin producing species at the site of their accumulation. The known phloroglucinols, hyperforin, adhyperforin, hyperfirin and some new phloroglucinols with m/z [M – H](-) 495 and 569 were localized in the translucent and pale cavities within the leaf in the majority of studied species. The comparison of different Hypericum species revealed an interspecific variation in the distribution of the dark and translucent glands corresponding with the localization of hypericins and phloroglucinols. Moreover, similarities in the localization and composition of the phloroglucinols were observed in the species belonging to the same section. Adding to various quantitative studies focused on the detection of secondary metabolites, this work using indirect DESI-MSI offers additional valuable information about localization of the above-mentioned compounds.
Interspecific variation in localization of hypericins and phloroglucinols in the genus Hypericum as revealed by desorption electrospray ionization mass spectrometry imaging
Andrea Kucharikova 1, Katarina Kimakova 1, Christian Janfelt 2, Eva cellarova 1
2016 May
19791496
Within the framework of our continuous efforts to explore Hypericum species from Jordan, we report the analysis of the major active metabolites, naphthodianthrones and phloroglucinols, in the methanolic extracts of two under-explored Hypericum species; H. empetrifolium Willd. and H. sinaicum Hochst. & Steud. ex Boiss., using LC-(+,-)-ESI-MS (TIC and SIM) and LC-UV/Vis spectroscopy. Based on their LC-UV/Vis profiles, retention times and (+,-)-ESI-MS (TIC and SIM) spectral data, hypericin, protohypericin and pseudohypericin were identified in both of the investigated species. In addition adhyperfirin was only detected in H. empetrifolium, while hyperforin and protopseudohypericin were only detected in H. sinaicum. This is the first report documenting the presence of hypericin, protohypericin, pseudohypericin, protopseudohypericin, and hyperforin in H. sinaicum, and adhyperfirin in H. empetrifolium.
LC-MS and LC-PDA analysis of Hypericum empetrifolium and Hypericum sinaicum
Feras Q Alali 1, Khaled Tawaha, Mohammad Gharaibeh
Jul-Aug 2009
18671196
10.1055/s-2008-1081337
Influence of the habitat altitude on the (proto)hypericin and (proto)pseudohypericin levels of hypericum plants from Crete
Marina Xenophontos 1, Ilias Stavropoulos, Emmanuel Avramakis, Eleni Navakoudis, Dieter Dornemann, Kiriakos Kotzabasis
2008 Oct;
Description :
Monatshefte für Chemie, 1992,123( 8-9):731-739. On the nature of “soluble” hypericin inHypericum species[Reference: WebLink]METHODS AND RESULTS:The two red and two violet “soluble” pigments ofHypericum species were isolated by means of extraction, chromatography, and counter-current droplet chromatography. In contrast to authentic hypericin, they are soluble in common organic solvents and even in water. Using NMR experiments it was deduced that hypericin, pseudohypericin, protohypericin, and Protopseudohypericin are present in the plant as their rapidly interconverting 3- and 4-phenolate ions. From AAS the main counter-ion of these phenolates was derived to be potassium. The potassium and N-ethyl-N,N-diisopropylammonium salts of hypericin were synthesizcd for comparison. CONCLUSIONS: A preparative procedure to isolate hypericin and pseudohypericin from plant material was developed.