White crystalline powder
(2E,4E)-5-[(1R,7S,8S,9R)-7-Acetoxy-4,9-dimethyl-11-oxo-10-oxatricyclo[126.96.36.199]tridec-3-en-9-yl]-2-methyl-2,4-pentadienoic acid/(2E,4E)-5-[(1R,7S,8S,9R)-7-Acetoxy-4,9-dimethyl-11-oxo-10-oxatricyclo[188.8.131.52]tridec-3-en-9-yl]-2-methylpenta-2,4-dienoic acid/2,4-Pentadienoic acid, 5-[(3R,4S,4aS,9aR)-4a-(acetyloxy)-3,4,4a,5,6,9-hexahydro-3,7-dimethyl-1-oxo-1H-4,9a-ethanocyclohepta[c]pyran-3-yl]-2-methyl-, (2E,4E)-/(2E,4E)-5-[(1R,7R,8S,9S)-7-Acetoxy-4,9-dimethyl-11-oxo-10-oxatricyclo[184.108.40.206]tridec-3-en-9-yl]-2-methyl-2,4-pentadienoic acid/(2E,4E)-5-[(3R,4S,4aS,9aR)-4a-(acetyloxy)-3,7-dimethyl-1-oxo-3,4,4a,5,6,9-hexahydro-4,9a-ethanocyclohepta[c]pyran-3(1H)-yl]-2-methylpenta-2,4-dienoic acid/pseudolaric acid A/2,4-Pentadienoic acid, 5-[(3S,4S,4aR,9aR)-4a-(acetyloxy)-3,4,4a,5,6,9-hexahydro-3,7-dimethyl-1-oxo-1H-4,9a-ethanocyclohepta[c]pyran-3-yl]-2-methyl-, (2E,4E)-/PseudolaricAcid A
Pseudolaric Acid A is a diterpene acid isolated from Pseudolarix kaempferi, has antifungal, cytotoxic and antifertile activities.
Methanol; Acetontrile; DMSO
571.5±50.0 °C at 760 mmHg
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Personal Projective Equipment
For Reference Standard and R&D, Not for Human Use Directly.
provides coniferyl ferulate(CAS#:82508-32-5) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate
A new strategy for the stereoselective total synthesis of natural product pseudolaric acid A (1) was accomplished in 16 steps from commercially available starting material, featuring a samarium diiodide (SmI(2))-mediated intramolecular alkene-ketyl radical cyclization and a ring-closing metathesis (RCM) reaction to stereoselectively cast the unusual trans-fused [5-7]-bicyclic core of pseudolaric acid A (1).
A concise approach for the total synthesis of pseudolaric acid A.
Xu T1, Li CC, Yang Z.
2011 May 20
Total synthesis of pseudolaric acid A.
Geng Z1, Chen B, Chiu P.
2006 Sep 18
Pseudolaric acid-A and -B, the novel diterpene acids isolated from Pseudolarix kaempferi, and their related derivatives have been tested for cytotoxicity against KB, A-549, HCT-8, P-388, and L-1210 tumor cells. The results showed that pseudolaric acid-A and -B demonstrated potent cytotoxicity. The selectivity of pseudolaric acid-A and -B which inhibit the growth of particular cell types within the disease-oriented human cancer cell line panels is discussed.
The cytotoxic principles of Pseudolarix kaempferi: pseudolaric acid-A and -B and related derivatives.
Pan DJ1, Li ZL, Hu CQ, Chen K, Chang JJ, Lee KH.