We Offer Worldwide Shipping
Login Wishlist

Pterostilbene

$78

  • Brand : BIOFRON

  • Catalogue Number : BF-P3023

  • Specification : 98%

  • CAS number : 537-42-8

  • Formula : C16H16O3

  • Molecular Weight : 256.3

  • PUBCHEM ID : 5281727

  • Volume : 25mg

In stock

Quantity
Checkout Bulk Order?

Catalogue Number

BF-P3023

Analysis Method

HPLC,NMR,MS

Specification

98%

Storage

2-8°C

Molecular Weight

256.3

Appearance

White crystalline powder

Botanical Source

Dracaena cochinchinensis,Caragana acanthophylla,Dalbergia cochinchinensis

Structure Type

Stilbenes

Category

Standards;Natural Pytochemical;API

SMILES

COC1=CC(=CC(=C1)C=CC2=CC=C(C=C2)O)OC

Synonyms

4-(3,5-Dimethoxystyryl)phenol/4-[(E)-2-(3,5-Dimethoxyphenyl)ethenyl]phenol/Phenol, 4-(2-(3,5-dimethoxyphenyl)ethenyl)-, (E)-/3,5-Dimethoxy-4'-hydroxy-trans-stilbene/3',5'-Dimethoxy-4-stilbenol/4-(2-(3,5-Dimethoxyphenyl)ethenyl)phenol/4-[(E)-2-(3,5-Dimethoxyphenyl)vinyl]phenol/(E)-4-(3,5-Dimethoxystyryl)phenol/trans-1-(3,5-Dimethoxyphenyl)-2-(4-hydroxyphenyl)ethylene/Pterostilbene/4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]phenol/Phenol, 4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]-/Pterostilbene,Pterocarpus marsupium/(E)-pterostilbene/4-Stilbenol, 3',5'-dimethoxy-, (E)-/3,5-dimethoxy-4'-hydroxystilbene/4'-hydroxy-3,5-dimethoxystilbene/4'-Hydroxy-3,5-dimethoxy-trans-stilbene

IUPAC Name

4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]phenol

Density

1.2±0.1 g/cm3

Solubility

Methanol; Chloroform

Flash Point

208.1±25.9 °C

Boiling Point

420.5±35.0 °C at 760 mmHg

Melting Point

89-92ºC

InChl

InChl Key

WGK Germany

RID/ADR

HS Code Reference

2909500000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:537-42-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

PMID

29168580

Abstract

Resveratrol is a natural phytoestrogen with neuroprotective properties. Polyphenolic compounds including resveratrol exert in vitro antioxidant, anti-inflammatory, and antiamyloid effects. Resveratrol and its derivative pterostilbene are able to cross the blood-brain barrier and to influence brain activity. The present short review summarizes the available evidence regarding the effects of these polyphenols on pathology and cognition in animal models and human subjects with dementia. Numerous investigations in cellular and mammalian models have associated resveratrol and pterostilbene with protection against dementia syndromes such as Alzheimer’s disease (AD) and vascular dementia. The neuroprotective activity of resveratrol and pterostilbene demonstrated in in vitro and in vivo studies suggests a promising role for these compounds in the prevention and treatment of dementia. In comparison to resveratrol, pterostilbene appears to be more effective in combatting brain changes associated with aging. This may be attributed to the more lipophilic nature of pterostilbene with its two methoxyl groups compared with the two hydroxyl groups of resveratrol. The findings of available intervention trials of resveratrol in individuals with mild cognitive impairment or AD do not provide evidence of neuroprotective or therapeutic effects. Future clinical trials should be conducted with long-term exposure to preparations of resveratrol and pterostilbene with high bioavailability.

© 2017 BioFactors, 44(1):83-90, 2018.

KEYWORDS

cognition; dementia; polyphenols; pterostilbene; resveratrol

Title

Resveratrol, pterostilbene, and dementia.

Author

Lange KW1, Li S2.

Publish date

2018 Jan

PMID

29210129

Abstract

Over the past years, several studies have found that foods rich in polyphenols protect against age-related disease, such as atherosclerosis, cardiovascular disease, cancer, arthritis, cataracts, osteoporosis, type 2 diabetes (T2D), hypertension and Alzheimer’s disease. Resveratrol and pterostilbene, the polyphenol found in grape and blueberries, have beneficial effects as anti-aging compounds through modulating the hallmarks of aging, including oxidative damage, inflammation, telomere attrition and cell senescence. In this review, we discuss the relationship between resveratrol and pterostilbene and possible aging biomarker, including oxidative stress, inflammation, and high-calorie diets. Moreover, we also discuss the positive effect of resveratrol and pterostilbene on lifespan, aged-related disease, and health maintenance. Furthermore, we summarize a variety of important mechanisms modulated by resveratrol and pterostilbene possibly involved in attenuating age-associated disorders. Overall, we describe resveratrol and pterostilbene potential for prevention or treatment of several age-related diseases by modulating age-related mechanisms.

© 2017 BioFactors, 44(1):69-82, 2018.

KEYWORDS

aging; healthspan; lifespan; pterostilbene; resveratrol

Title

Effect of resveratrol and pterostilbene on aging and longevity.

Author

Li YR1,2, Li S3, Lin CC2,4,5.

Publish date

2018 Jan

PMID

29315886

Abstract

Beneficial properties of resveratrol and pterostilbene, a dimethyl ether analog of resveratrol, have attracted increasing interest in recent years. Resveratrol and pterostilbene exhibit many pharmacological similarities and both of them are generally considered to be safe for human consumption. Beyond the structural and general bioactivity similarities between them, large amounts of data are now available to reveal the metabolic fate and pharmacological differences between them. Pterostilbene was found to be more metabolically stable and usually exhibited stronger pharmacological activities than that of resveratrol. As a contribution to clarify and compare aspects like metabolic stability and pharmacokinetics of resveratrol and pterostilbene, as well as explain the pharmacological similarities and differences between them, this review presents and compares recent data on the metabolism and pharmacokinetics of resveratrol and pterostilbene.

© 2018 BioFactors, 44(1):16-25, 2018.

KEYWORDS

metabolism; pharmacokinetics; pharmacological activities; pterostilbene; resveratrol

Title

Metabolism and pharmacokinetics of resveratrol and pterostilbene.

Author

Wang P1, Sang S1.

Publish date

2018 Jan


Description :

Pterostilbene is a stilbenoid isolated from blueberries and Pterocarpus marsupium[1]. Shows anti-oxidant, anti-inflammatory, anti-carcinogenic, anti-diabetic and anti-obesity properties[1][4]. Pterostilbene blocks ROS production[3], also exhibits inhibitory activity against various free radicals such as DPPH, ABTS, hydroxyl, superoxide and hydrogen peroxide[4].