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Quinovic acid

$1,152

  • Brand : BIOFRON

  • Catalogue Number : BN-O1625

  • Specification : 98%(HPLC)

  • CAS number : 465-74-7

  • Formula : C30H46O5

  • Molecular Weight : 486.7

  • PUBCHEM ID : 120678

  • Volume : 5mg

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Catalogue Number

BN-O1625

Analysis Method

HPLC,NMR,MS

Specification

98%(HPLC)

Storage

-20℃

Molecular Weight

486.7

Appearance

Powder

Botanical Source

This product is isolated and purified from the herbs of Mitragyna rotundifolia

Structure Type

Triterpenoids

Category

Standards;Natural Pytochemical;API

SMILES

CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)O)C)C)C2C1C)C(=O)O)C(=O)O

Synonyms

(3β)-3-Hydroxyurs-12-ene-27,28-dioic acid/quinovic acid/Chinovic acid/Quinovaic acid/3-β-Hydroxyurs-12-ene-27,28-dioic acid/Urs-12-ene-27,28-dioic acid, 3-hydroxy-, (3β)-/Chinova acid

IUPAC Name

(1S,2R,4aS,6aR,6aR,6bR,8aR,10S,12aR,14bS)-10-hydroxy-1,2,6b,9,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a,6a-dicarboxylic acid

Applications

Density

1.2±0.1 g/cm3

Solubility

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

Flash Point

343.9±28.0 °C

Boiling Point

621.9±55.0 °C at 760 mmHg

Melting Point

298°C (rough estimate)

InChl

InChI=1S/C30H46O5/c1-17-9-14-29(24(32)33)15-16-30(25(34)35)19(23(29)18(17)2)7-8-21-27(5)12-11-22(31)26(3,4)20(27)10-13-28(21,30)6/h7,17-18,20-23,31H,8-16H2,1-6H3,(H,32,33)(H,34,35)/t17-,18+,20+,21-,22+,23+,27+,28-,29+,30-/m1/s1

InChl Key

OJUYFGQEMPENCE-DPKHZRJYSA-N

WGK Germany

RID/ADR

HS Code Reference

2918190000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:465-74-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

17402003

Abstract

Two glycosides, isolated in good yields from roots of Macfadyena unguis-cati (L.) A. G entry (syn. Doxantha unguis-cati (L.) Miers), gave on hydrolysis the same aglycone (quinovic acid). The sugar moieties have been identified as fucose and glucose respectively. This is the first time that saponins have been found in Bignoniaceae and their occurrence may account of the use of the plant in folk medicine.

Title

Quinovic acid glycosides from roots of Macfadyena unguis-cati

Author

Ferrari F1, Kiyan de Cornelio I, Delle Monache F, Marini Bettolo GB

Publish date

1981 Sep

PMID

1367339

Abstract

From the bark of Uncaria guianensis, two new quinovic acid glycosides, quinovic acid 3 beta-O-beta-D-quinovopyranoside and quinovic acid 3 beta-O-beta-D-fucopyranosyl-(27—-1)-beta-D-glucopyranosylester, have been isolated, in addition to known quinovic acid 3 beta-O-[beta-D-glucopyranosyl-(1—-3)-beta-D-fucopyranosyl]-(27—-1)- beta-D-glucopyranosylester and quinovic acid 3 beta-O-beta-D-fucopyranoside. Their structures were elucidated by spectral and chemical studies.

Title

Quinovic acid glycosides from Uncaria guianensis

Publish date

1991

PMID

17089325

Abstract

Nine quinovic acid glycosides and the alkaloid cadambine acid isolated from N. diderrichii, an evergreen endemic plant of West and Central Africa, were assessed for their in vitro antileishmanial activity against Leishmania infantum. Four quinovic acid glycosides and cadambine acid revealed a strong antileishmanial activity (IC (50) = 1 microM) highly specific for the intracellular amastigote form of the parasite. Quinovic acid glycosides were shown to inhibit parasite internalisation by interfering with promastigotes while cadambine acid exerted immunomodulatory activity by inducing NO production in human macrophages. The association of cadambine acid with amphotericin B demonstrated an interesting synergism, suggesting that cadambine acid could be used as a complement of such conventional therapy.

Title

Antileishmanial activity of quinovic acid glycosides and cadambine acid isolated from Nauclea diderrichii

Publish date

2006 Dec