White crystalline powder
Vitis vinifera,Morus alba,Paeonia suffruticosa,Dracaena cochinchinensis,Reynoutria japonica
5-[(E)-2-(4-Hydroxyphenyl)ethenyl]benzol-1,3-diol/1,3-Benzenediol, 5-[(E)-2-(4-hydroxyphenyl)ethenyl]-/RESVERTROL/3',4,5'-trihydroxy-trans-stilbene/1,3-Benzenediol, 5-(2-(4-hydroxyphenyl)ethenyl)-, (E)-/3,4',5-Trihydroxy-trans-stilbene/(E)-5-(p-Hydroxystyryl)resorcinol/trans-3,5,4'-trihydroxy-stilbene/5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol/(E)-5-[2-(4-hydroxyphenyl)ethenyl]-1,3-benzendiol/3,5,4'-Trihydroxy-trans-stilbene/5-[(E)-2-(4-Hydroxyphenyl)vinyl]benzene-1,3-diol/RESVERATROLE/3,4',5-trihydroxy-stilbene/Resveratrol/TRANS-RESVERATROL/5-[(E)-2-(4-Hydroxyphenyl)vinyl]-1,3-benzenediol/5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol/trans-1,2-(3,4',5-Trihydroxydiphenyl)ethylene/(E)-5-(4-hydroxystyryl)benzene-1,3-diol/5-[2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol
449.1±14.0 °C at 760 mmHg
HS Code Reference
Personal Projective Equipment
For Reference Standard and R&D, Not for Human Use Directly.
provides coniferyl ferulate(CAS#:501-36-0) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate
The present study was designed to examine the potential preventive effect of curcumin (CMN; CAS 458-37-7), rosiglitazone (RGN; CAS 155141-29-0), N-acetylcysteine (NAC; CAS 616-91-1), resveratrol (RSV; CAS 501-36-0), and losartan (LOS; CAS 114798-26-4) on sodium valproate-induced hepatotoxicity. Sodium valproate (SVP; CAS 1069-66-5) was given at a dose of 250 mg/kg i. p. 3 times daily for one week. The tested compounds were given simultaneously with SVP for one week. The results demonstrate that CMN, RGN and NAC treatment can confer protection from SVP-induced hepatotoxicity. The second part of the study includes an evaluation of the effect of CMN, RGN and NAC on the anticonvulsant activity of SVP against pentetrazole-induced seizures in mice. The results demonstrate that CMN, RGN and NAC do not affect the anticonvulsant activity of SVP. Combined administration of either of CMN, RGN and NAC with valproate appears to be beneficial in reducing valproate-induced hepatotoxicity.
Prevention of sodium valproate-induced hepatotoxicity by curcumin, rosiglitazone and N-acetylcysteine in rats.
Said SA1, El-Agamy DS.
Resveratrol (trans-3,4′,5-trihydroxystilbene, CAS 501-36-0), a natural antioxidant and polyphenol found in grapes and wine, has been found to pharmacologically precondition the heart in nitric oxide (NO)-dependent manner. In the vascular system, NO functions as an endogenous inhibitor of leukocyte chemotaxis, adherence, and activation. The present study was designed to determine if resveratrol, through NO, can block the proadhesive molecules generated in the ischemic reperfused myocardium. Isolated hearts were prepared from properly anesthetized rats, and mounted on a Langendorff apparatus. The hearts were randomly assigned to one of the three groups: (i) control, (ii) resveratrol, and (iii) resveratrol + NG-nitro-L-arginine ethyl ester (L-NAME). The hearts were perfused in the absence (n = 6) or presence of 10 micromol/L resveratrol (n=6) or resveratrol + L-NAME (n = 6) for 15 min. All the hearts were then subjected to 30 min ischemia followed by 2 h of reperfusion. Ventricular function was monitored, infarct size and apoptotic cell death measured, and the proadhesive molecules and malonaldehyde formation determined in the perfusate. Resveratrol significantly improved postischemic ventricular function and reduced myocardial infarct size compared to the non-treated control group. The amount of proadhesive molecules including soluble intracellular adhesion molecule-1 (sICAM-1), endothelial leukocyte adhesion molecule-1 (sE-Selectin) and vascular cell adhesion molecule-1 (sVCAM-1) were each significantly decreased during reperfusion in the resveratrol group. L-NAME, a NO blocker, completely abolished such beneficial effects of resveratrol. The results support an anti-inflammatory action of resveratrol through a NO-dependent mechanism.
Attenuation of ischemia/reperfusion injury in rats by the anti-inflammatory action of resveratrol.
Das S1, Falchi M, Bertelli A, Maulik N, Das DK.
Resveratrol (SRT 501), a natural polyphenol that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. It has a wide spectrum of targets including mTOR, JAK, β-amyloid.