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Rhodiosin

$476

  • Brand : BIOFRON

  • Catalogue Number : BD-P0604

  • Specification : 98.0%(HPLC)

  • CAS number : 86831-54-1

  • Volume : 25mg

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Catalogue Number

BD-P0604

Analysis Method

HPLC,NMR,MS

Specification

98.0%(HPLC)

Storage

2-8°C

Molecular Weight

Appearance

Botanical Source

Structure Type

Category

SMILES

CC1C(C(C(C(O1)OC2=C(C3=C(C(=C2)O)C(=O)C(=C(O3)C4=CC=C(C=C4)O)O)O)O)OC5C(C(C(C(O5)CO)O)O)O)O

Synonyms

herbacetin 7-O-(3'-O-β-D-glucopyranosyl-α-L-rhamnopyranoside)/3,5,8-Trihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl 6-deoxy-3-O-β-D-glucopyranosyl-α-L-mannopyranoside/Herbacetin-7-O-glucorhamnoside/4H-1-BENZOPYRAN-4-ONE,7-[(6-DEOXY-3-O-B-D-GLUCOPYRANOSYL-A-L-MANNOPYRANOSYL)OXY]-3,5,8-TRIHYDROXY-2-(4-HYDROXYPHENYL)-/4H-1-Benzopyran-4-one, 7-[(6-deoxy-3-O-β-D-glucopyranosyl-α-L-mannopyranosyl)oxy]-3,5,8-trihydroxy-2-(4-hydroxyphenyl)-/Rhodiosin

IUPAC Name

Applications

Density

1.8±0.1 g/cm3

Solubility

Alcohol water mixed solvent

Flash Point

329.1±27.8 °C

Boiling Point

994.3±65.0 °C at 760 mmHg

Melting Point

InChl

InChl Key

WGK Germany

RID/ADR

HS Code Reference

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:86831-54-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

31356124

Abstract

Context: Rhodiola rosea L. (Crassulaceae) is well-known to contain flavonoids such as the herbacetin derivative rhodiosin. However, flavonoids are not typically used in quality control. Objective: This study analyses two flavonoids of R. rosea rhizomes and roots for their potential as analytical markers. Materials and methods: Two constituents were isolated from ethanolic extracts via HPLC, identified via NMR and quantified via RP-HPLC. Presence and content variation was investigated according to extraction (solvent and repetitions), drying (temperature and duration) and sample origin (homogenously cultivated plants of different provenance, commercial samples). Results: Rhodiosin was identified as a main flavonoid, accompanied by 10-fold lower concentrated herbacetin. Both compounds were best extracted with 70-90% ethanol, but were also detectable in more aqueous extracts. Different drying conditions had no effect on the flavonoid content. These two flavonoids were consistently identified in rhizome and root extracts of over 100 R. rosea samples. Rhizomes tend to contain less flavonoids, with average ratios of rosavins to flavonoids of 1.4 (rhizomes) and 0.4 (roots). Provenance differences were detected in the range (rhodiosin plus herbacetin) of 760-6300 µg/mL extract corresponding to a maximum of approximately 0.5-4.2% (w/w) in the dry drug. Conclusions: For the first time, two main flavonoids present in R. rosea were quantified systematically. Rhodiosin and herbacetin can be detected simultaneously to phenylpropenoids or salidroside in authentic samples, influenced by the plant part examined and the plant origin. Rhodiosin and herbacetin may serve as additional marker to guarantee a consistent content of R. rosea products.

KEYWORDS

HPLC; flavonoid

Title

Rhodiosin and herbacetin in Rhodiola rosea preparations: additional markers for quality control?

Author

Peter Zomborszki Z1,2, Kúsz N1,2, Csupor D1,2, Peschel W3.

Publish date

2019 Dec