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Salicylic acid


  • Brand : BIOFRON

  • Catalogue Number : BF-S3016

  • Specification : 98%

  • CAS number : 69-72-7

  • Formula : C7H6O3

  • Molecular Weight : 138.12

  • PUBCHEM ID : 338

  • Volume : 25mg

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Catalogue Number


Analysis Method






Molecular Weight



White crystalline powder

Botanical Source

Leonurus japonicus,Morus alba,Myrica rubra,Pueraria montana var. lobata,Trifolium pratense

Structure Type



Standards;Natural Pytochemical;API




Verrugon/Acid, Salicylic/Duoplant/Freezone/Acid, o-Hydroxybenzoic/SAX/Saligel/Hydroxybenzenecarboxylic acid/Salonil/phenol-carboxylic acid/Stri-Dex/Benzoic acid, 2-hydroxy-/ORTHO-HYDROXYBENZOIC ACID/2-Hydroxybenzenecarboxylic acid/2 Hydroxybenzoic Acid/Salicylic acid/Acid, 2-Hydroxybenzoic/Benzoic acid, o-hydroxy-/2-hydroxy-benzoic acid/ortho Hydroxybenzoic Acid/Ionil/2-hydroxybenzoic acid/Acid, ortho-Hydroxybenzoic/o-hydroxybenzoic acid/Duofilm/Rutranex/Keralyt/Lamivudine Impurity 3


2-hydroxybenzoic acid


1.4±0.1 g/cm3


Methanol; Water

Flash Point

144.5±19.1 °C

Boiling Point

336.3±0.0 °C at 760 mmHg

Melting Point

158-161 °C(lit.)


InChl Key

WGK Germany


HS Code Reference


Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:69-72-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate




This article is part of the Distinguished Review Article Series in Conceptual and Methodological Breakthroughs in Molecular Plant-Microbe Interactions. Salicylic acid (SA) is a critical plant hormone that regulates numerous aspects of plant growth and development as well as the activation of defenses against biotic and abiotic stress. Here, we present a historical overview of the progress that has been made to date in elucidating the role of SA in signaling plant immune responses. The ability of plants to develop acquired immunity after pathogen infection was first proposed in 1933. However, most of our knowledge about plant immune signaling was generated over the last three decades, following the discovery that SA is an endogenous defense signal. During this timeframe, researchers have identified i) two pathways through which SA can be synthesized, ii) numerous proteins that regulate SA synthesis and metabolism, and iii) some of the signaling components that function downstream of SA, including a large number of SA targets or receptors. In addition, it has become increasingly evident that SA does not signal immune responses by itself but, rather, as part of an intricate network that involves many other plant hormones. Future efforts to develop a comprehensive understanding of SA-mediated immune signaling will therefore need to close knowledge gaps that exist within the SA pathway itself as well as clarify how crosstalk among the different hormone signaling pathways leads to an immune response that is both robust and optimized for maximal efficacy, depending on the identity of the attacking pathogen.


Systemic Acquired Resistance and Salicylic Acid: Past, Present, and Future.


Klessig DF1, Choi HW1, Dempsey DA1.

Publish date

2018 Sep




Salicylic acid (SA) is a phytohormone that plays important roles in many aspects of plant life, notably in plant defenses against pathogens. Key mechanisms of SA signal transduction pathways have now been uncovered. Even though details are still missing, we understand how SA production is regulated and which molecular machinery is implicated in the control of downstream transcriptional responses. The NPR1 pathway has been described to play the main role in SA transduction. However, the mode of SA perception is unclear. NPR1 protein has been shown to bind SA. Nevertheless, NPR1 action requires upstream regulatory events (such as a change in cell redox status). Besides, a number of SA-induced responses are independent from NPR1. This shows that there is more than one way for plants to perceive SA. Indeed, multiple SA-binding proteins of contrasting structures and functions have now been identified. Yet, all of these proteins can be considered as candidate SA receptors and might have a role in multinodal (decentralized) SA input. This phenomenon is unprecedented for other plant hormones and is a point of discussion of this review.


NPR1; SABP; Salicylic acid; pathogens; salicylic acid binding protein; stress response


Salicylic Acid Binding Proteins (SABPs): The Hidden Forefront of Salicylic Acid Signalling.


Pokotylo I1,2, Kravets V1, Ruelland E3,4.

Publish date

2019 Sep 6




As more evidence emerges supporting the possibility that nonsteroidal anti-inflammatory drugs, especially aspirin (acetyl salicylic acid), might have a role in the prevention and management of certain types of cancer, there have been several attempts to fabricate salicylic acid-based polymers that can be employed in the targeted therapy of tumors. The primary disadvantage so far has been in use of nontherapeutic polymeric backbones that constitute the majority of the therapeutic particle’s size. The focus of this research is the creation of a biodegradable polymer consisting only of salicylic acid, and its use as the main building block in targeted nanotherapeutics that would consequently provide both high local dose and sustained release of the active moiety. This work demonstrates the synthesis and degradation of polysalicylates, and modulation of their size and hydrolytic stability through the formation of nanostructures.

© 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


block copolymers; degradable polymers; polymer prodrugs; salicylic acid


Degradable Polymers and Nanoparticles Built from Salicylic Acid.


Akkad S1, Serpell CJ1.

Publish date

2018 Jul

Description :

Salicylic acid inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation.