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Scabertopin

$1,143

  • Brand : BIOFRON

  • Catalogue Number : BD-P0498

  • Specification : 98.0%(HPLC)

  • CAS number : 185213-52-9

  • Formula : C20H22O6

  • Molecular Weight : 358.39

  • PUBCHEM ID : 21575211

  • Volume : 25mg

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Catalogue Number

BD-P0498

Analysis Method

HPLC,NMR,MS

Specification

98.0%(HPLC)

Storage

-20℃

Molecular Weight

358.39

Appearance

White crystalline powder

Botanical Source

Elephantopus scaber

Structure Type

Sesquiterpenoids

Category

Standards;Natural Pytochemical;API

SMILES

CC=C(C)C(=O)OC1CC2=CC(CC(=CC3C1C(=C)C(=O)O3)C)OC2=O

Synonyms

2-Butenoic acid, 2-methyl-, (3aR,4S,9S,11Z,12aR)-2,3,3a,4,5,9,10,12a-octahydro-11-methyl-3-methylene-2,7-dioxo-7H-9,6-methenofuro[2,3-f]oxacycloundecin-4-yl ester, (2Z)-/(3S,4R,8R,9Z,12S)-10-Methyl-5-methylene-6,14-dioxo-7,13-dioxatricyclo[10.2.1.0]pentadeca-1(15),9-dien-3-yl (2Z)-2-methyl-2-butenoate

IUPAC Name

[(3S,4R,8R,9E,12S)-10-methyl-5-methylidene-6,14-dioxo-7,13-dioxatricyclo[10.2.1.04,8]pentadeca-1(15),9-dien-3-yl] (Z)-2-methylbut-2-enoate

Applications

Scabertopin, isolated from the whole plant of Elephantopus scaber[1], is a sesquiterpene lactone. Scabertopin has been found to be prominent anticancer constituents[2].

Density

1.2±0.1 g/cm3

Solubility

Methanol

Flash Point

260.5±30.2 °C

Boiling Point

592.7±50.0 °C at 760 mmHg

Melting Point

InChl

InChI=1S/C20H22O6/c1-5-11(3)18(21)25-16-9-13-8-14(24-20(13)23)6-10(2)7-15-17(16)12(4)19(22)26-15/h5,7-8,14-17H,4,6,9H2,1-3H3/b10-7+,11-5-/t14-,15+,16-,17-/m0/s1

InChl Key

FTPHYXGWMIZVMP-RZYABJHASA-N

WGK Germany

RID/ADR

HS Code Reference

2933990000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:185213-52-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

29736139

Abstract

Three new species of the genus Plato from caves in the states of Para and Minas Gerais, Brazil, are described. P. novalima sp. n., from Minas Gerais, is the first record of the genus in the southeastern region of Brazil. P. ferriferus sp. n. and P. striatus sp. n., from Carajas, Para, north of Brazil, are also described. The former is an extremely abundant species, whereas the latter has only one known male specimen. Cuacuba gen. n. is proposed and represented by two new species, C. mariana sp. n. (type species) and C. morrodopilar sp. n., both from the state of Minas Gerais. Morphology of genitalia in Cuacuba gen. n. is similar to other Theridiosomatidae genera and is herein discussed. None of the proposed species presents troglomorphic adaptations. They are widespread, abundant inside caves in different and large karst areas, and each genus prefers different lithologies.

KEYWORDS

biospeleology, Neotropical region, taxonomy

Title

Three new species of the spider genus Plato and the new genus Cuacuba from caves of the states of Para and Minas Gerais, Brazil (Araneae, Theridiosomatidae)

Author

Pedro H. Prete,1 Igor Cizauskas,1 and Antonio D. Brescovit1

Publish date

2018

PMID

29629519

Abstract

Background
This study aims to determine whether significant associations exist between the parents’ country of birth and adolescent depressive symptoms in the early stages of a multicultural society.

Methods
We used data from the 2012-2016 Korea Youth Risk Behavior Web-based Survey, which included responses from 327,357 individuals. Participants were classified into groups according to their parent’s country of birth. Logistic regression analysis was used to examine the significance of the associations.

Results
Adolescents whose parents were born abroad are more likely to have depressive symptoms (odds ratio [OR] = 1.68; 95% confidence interval [CI], 1.33-2.12) than adolescents whose parents were native Koreans. Respondents whose father was born in North Korea or Japan or Taiwan show greater odds of depressive symptoms than respondents whose parents were native Korean.

Conclusion
Adolescents whose parents were born abroad are more likely to have depressive symptoms. Multicultural family support policies should be implemented in consideration of the characteristics of the parents’ country of birth.

KEYWORDS

Multicultural, Depression, Adolescent, Parents' Birth of Country, Migration

Title

Association between Parents' Country of Birth and Adolescent Depressive Symptoms: the Early Stages of Multicultural Society

Author

Jieun Jang,1,2 Eun-Cheol Park,2,3 Sang Ah Lee,1,2 Young Choi,1,2 Yoon Soo Choy,1,2 Woorim Kim,1,2 and Sung-In Jangcorresponding author2,3

Publish date

2018 Apr 9;

PMID

26423836

Abstract

Background
Dermoscopy is a highly effective and noninvasive imaging technique used in diagnosis of melanoma and other pigmented skin lesions. Many aspects of the lesion under consideration are defined in relation to the lesion border. This makes border detection one of the most important steps in dermoscopic image analysis. In current practice, dermatologists often delineate borders through a hand drawn representation based upon visual inspection. Due to the subjective nature of this technique, intra- and inter-observer variations are common. Because of this, the automated assessment of lesion borders in dermoscopic images has become an important area of study.

Methods
Fast density based skin lesion border detection method has been implemented in parallel with a new parallel technology called WebCL. WebCL utilizes client side computing capabilities to use available hardware resources such as multi cores and GPUs. Developed WebCL-parallel density based skin lesion border detection method runs efficiently from internet browsers.

Results
Previous research indicates that one of the highest accuracy rates can be achieved using density based clustering techniques for skin lesion border detection. While these algorithms do have unfavorable time complexities, this effect could be mitigated when implemented in parallel. In this study, density based clustering technique for skin lesion border detection is parallelized and redesigned to run very efficiently on the heterogeneous platforms (e.g. tablets, SmartPhones, multi-core CPUs, GPUs, and fully-integrated Accelerated Processing Units) by transforming the technique into a series of independent concurrent operations. Heterogeneous computing is adopted to support accessibility, portability and multi-device use in the clinical settings. For this, we used WebCL, an emerging technology that enables a HTML5 Web browser to execute code in parallel for heterogeneous platforms. We depicted WebCL and our parallel algorithm design. In addition, we tested parallel code on 100 dermoscopy images and showed the execution speedups with respect to the serial version. Results indicate that parallel (WebCL) version and serial version of density based lesion border detection methods generate the same accuracy rates for 100 dermoscopy images, in which mean of border error is 6.94%, mean of recall is 76.66%, and mean of precision is 99.29% respectively. Moreover, WebCL version’s speedup factor for 100 dermoscopy images’ lesion border detection averages around ~491.2.

Conclusions
When large amount of high resolution dermoscopy images considered in a usual clinical setting along with the critical importance of early detection and diagnosis of melanoma before metastasis, the importance of fast processing dermoscopy images become obvious. In this paper, we introduce WebCL and the use of it for biomedical image processing applications. WebCL is a javascript binding of OpenCL, which takes advantage of GPU computing from a web browser. Therefore, WebCL parallel version of density based skin lesion border detection introduced in this study can supplement expert dermatologist, and aid them in early diagnosis of skin lesions. While WebCL is currently an emerging technology, a full adoption of WebCL into the HTML5 standard would allow for this implementation to run on a very large set of hardware and software systems. WebCL takes full advantage of parallel computational resources including multi-cores and GPUs on a local machine, and allows for compiled code to run directly from the Web Browser.

Title

Density-based parallel skin lesion border detection with webCL

Author

James Lemon,1 Sinan Kockara,corresponding author1 Tansel Halic,1 and Mutlu Mete2

Publish date

2015;