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Simiarenol

$960

  • Brand : BIOFRON

  • Catalogue Number : BN-O1458

  • Specification : 98%(HPLC)

  • CAS number : 1615-94-7

  • Formula : C30H50O

  • Molecular Weight : 426.7

  • PUBCHEM ID : 12442794

  • Volume : 5mg

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Catalogue Number

BN-O1458

Analysis Method

HPLC,NMR,MS

Specification

98%(HPLC)

Storage

-20℃

Molecular Weight

426.7

Appearance

Cryst.

Botanical Source

This product is isolated and purified from the root of Rhododendron dauricum L.

Structure Type

Triterpenoids

Category

Standards;Natural Pytochemical;API

SMILES

CC(C)C1CCC2C1(CCC3(C2(CCC4(C3CC=C5C4CCC(C5(C)C)O)C)C)C)C

Synonyms

Simiarenol/1H-Cyclopenta[a]chrysen-9-ol, 2,3,3a,4,5,5a,5b,6,8,9,10,11,11a,11b,12,13,13a,13b-octadecahydro-3a,5a,8,8,11b,13a-hexamethyl-3-(1-methylethyl)-, (3R,3aR,5aR,5bS,9S,11aS,11bR,13aS,13bR)-/(3R,3aR,5aR,5bS,9S,11aS,11bR,13aS,13bR)-3-Isopropyl-3a,5a,8,8,11b,13a-hexamethyl-2,3,3a,4,5,5a,5b,6,8,9,10,11,11a,11b,12,13,13a,13b-octadecahydro-1H-cyclopenta[a]chrysen-9-ol/(3R,3aR,5aR,5bS,9S,11aS,11bR,13aS,13bR)-3a,5a,8,8,11b,13a-hexamethyl-3-(propan-2-yl)-2,3,3a,4,5,5a,5b,6,8,9,10,11,11a,11b,12,13,13a,13b-octadecahydro-1H-cyclopenta[a]chrysen-9-ol/Simiaren-3beta-ol

IUPAC Name

(3R,3aR,5aR,5bS,9S,11aS,11bR,13aS,13bR)-3a,5a,8,8,11b,13a-hexamethyl-3-propan-2-yl-1,2,3,4,5,5b,6,9,10,11,11a,12,13,13b-tetradecahydrocyclopenta[a]chrysen-9-ol

Density

1.0±0.1 g/cm3

Solubility

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

Flash Point

218.8±12.4 °C

Boiling Point

494.5±14.0 °C at 760 mmHg

Melting Point

InChl

InChI=1S/C30H50O/c1-19(2)20-9-12-23-27(20,5)15-17-30(8)24-13-10-21-22(11-14-25(31)26(21,3)4)28(24,6)16-18-29(23,30)7/h10,19-20,22-25,31H,9,11-18H2,1-8H3/t20-,22-,23-,24+,25+,27-,28+,29+,30-/m1/s1

InChl Key

XVXPXUMUGATHPD-JMJRLLIOSA-N

WGK Germany

RID/ADR

HS Code Reference

2933990000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:1615-94-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

28734125

Abstract

The efficacy of cold in situ perfusion and static storage of the liver is a possible determinant of transplantation outcomes. The aim of this study was to determine whether there is evidence to substantiate a preference for a particular perfusion route (aortic or dual) or perfusion/preservation solution in donation after brain death (DBD) liver transplantation. The Embase, MEDLINE, and Cochrane databases were used (1980‐2017). Random effects modeling was used to estimate effects on transplantation outcomes based on (1) aortic or dual in situ perfusion and (2) the use of University of Wisconsin (UW), histidine tryptophan ketoglutarate (HTK), Celsior, and/or Institut Georges Lopez-1 (IGL‐1) solutions for perfusion/preservation. A total of 22 articles were included (2294 liver transplants). The quality of evidence ranged from very low to moderate Grading of Recommendations, Assessment, Development and Evaluations score. Meta‐analyses were conducted for 14 eligible studies. Although there was no difference in the primary nonfunction (PNF) rate, a higher peak alanine aminotransferase (ALT) was recorded in dual compared with aortic‐only UW‐perfused livers (standardized mean difference, 0.24; 95% confidence interval, 0.01‐0.47); a back‐table portal venous flush was undertaken in the majority of aortic‐only perfused livers. There were no relevant differences in peak enzymes, PNF, thrombotic graft loss, biliary complications, or 1‐year graft survival in comparisons between dual‐perfused livers using UW, HTK, Celsior, or IGL‐1. In conclusion, there is no significant evidence that aortic‐only perfusion of the DBD liver compromises transplantation outcomes, and it may be favored because of its simplicity. However, there is currently insufficient evidence to advocate for the use of any particular perfusion/preservation fluid over the others. Liver Transplantation 23 1615-1627 2017 AASLD.

Title

A systematic review and meta‐analysis of cold in situ perfusion and preservation of the hepatic allograft: Working toward a unified approach

Author

Ahmer M. Hameed, 1 , 2 , 3 Jerome M. Laurence, 3 , 4 , 5 Vincent W. T. Lam, 2 , 3 Henry C. Pleass, 2 , 3 , 4 and Wayne J. Hawthornecorresponding author 1 , 2 , 3

Publish date

2017 Dec;

PMID

23087037

Abstract

The U.S. EPA developed a sample concentration and preparation assay in conjunction with the total culturable virus assay for concentrating and measuring culturable viruses in source and drinking waters as part of the Information Collection Rule (ICR) promulgated in 1996. In an effort to improve upon this method, the U.S. EPA recently developed Method 1615: Measurement of Enterovirus and Norovirus Occurrence in Water by Culture and RT-qPCR. Method 1615 uses a culturable virus assay with reduced equipment and labor costs compared to the costs associated with the ICR virus method and introduces a new molecular assay for the detection of enteroviruses and noroviruses by reverse transcription-quantitative PCR. In this study, we describe the optimization of several new components of the molecular assay and examine virus recovery from ground, reagent-grade, and surface water samples seeded with poliovirus type 3 and murine norovirus. For the culturable virus and molecular assays, mean poliovirus recovery using the complete method was 58% and 20% in groundwater samples, 122% and 39% using low-titer spikes in reagent-grade water, 42% and 48% using high-titer spikes in reagent-grade water, and 11% and 10% in surface water with high turbidity, respectively. Murine norovirus recovery by the molecular assay was 30% in groundwater samples, less than 8% in both low- and high-titer spikes in reagent-grade water, and 6% in surface water with high turbidity. This study demonstrates the effectiveness of Method 1615 for use with groundwater samples and highlights the need for further research into its effectiveness with surface water.

Title

Development and Evaluation of EPA Method 1615 for Detection of Enterovirus and Norovirus in Water

Author

Jennifer L. Cashdollar, Nichole E. Brinkman, Shannon M. Griffin, Brian R. McMinn, Eric R. Rhodes, Eunice A. Varughese, Ann C. Grimm, Sandhya U. Parshionikar, Larry Wymer, G. Shay Fout

Publish date

2013 Jan;

PMID

21120123

Abstract

Study Objectives:
To determine the associations between deployment in support of the wars in Iraq and Afghanistan and sleep quantity and quality.

Design:
Longitudinal cohort study

Setting:
The Millennium Cohort Study survey is administered via a secure website or US mail.

Participants:
Data were from 41,225 Millennium Cohort members who completed baseline (2001-2003) and follow-up (2004-2006) surveys. Participants were placed into 1 of 3 exposure groups based on their deployment status at follow-up: nondeployed, survey completed during deployment, or survey completed postdeployment.

Measurements and Results:
Study outcomes were self-reported sleep duration and trouble sleeping, defined as having trouble falling asleep or staying asleep. Adjusted mean sleep duration was significantly shorter among those in the deployed and postdeployment groups compared with those who did not deploy. Additionally, male gender and greater stress were significantly associated with shorter sleep duration. Personnel who completed their survey during deployment or postdeployment were significantly more likely to have trouble sleeping than those who had not deployed. Lower self-reported general health, female gender, and reporting of mental health symptoms at baseline were also significantly associated with increased odds of trouble sleeping.

Conclusions:
Deployment significantly influenced sleep quality and quantity in this population though effect size was mediated with statistical modeling that included mental health symptoms. Personnel reporting combat exposures or mental health symptoms had increased odds of trouble sleeping. These findings merit further research to increase understanding of temporal relationships between sleep and mental health outcomes occurring during and after deployment.

Citation:
Seelig AD; Jacobson IG; Smith B; Hooper TI; Boyko EJ; Gackstetter GD; Gehrman P; Macera CA; Smith TC. Sleep patterns before, during, and after deployment to Iraq and Afghanistan. SLEEP 2010;33(12):1615-1622.

KEYWORDS

Sleep, deployment, Millennium Cohort, mental health, veterans

Title

Sleep Patterns Before, During, and After Deployment to Iraq and Afghanistan

Author

Amber D. Seelig, Isabel G. Jacobson, Besa Smith, Tomoko I. Hooper, Edward J. Boyko, Gary D. Gackstetter, Philip Gehrman, Carol A. Macera, Tyler C. Smith, for the Millennium Cohort Study Team

Publish date

2010 Dec 1


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