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Simulanol

$1,152

  • Brand : BIOFRON

  • Catalogue Number : BN-O0964

  • Specification : 95%(HPLC)

  • CAS number : 500574-38-9

  • Formula : C21H24O7

  • Molecular Weight : 388.41

  • PUBCHEM ID : 22297418

  • Volume : 5mg

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Catalogue Number

BN-O0964

Analysis Method

HPLC,NMR,MS

Specification

95%(HPLC)

Storage

2-8°C

Molecular Weight

388.41

Appearance

Powder

Botanical Source

Structure Type

Lignans

Category

Standards;Natural Pytochemical;API

SMILES

CC(C)(C)OC(=O)C(=CC1=CC=CO1)NC2=NC=C(N=C2CC3=CC=CC=C3)C4=C(C(=CC=C4)[N+](=O)[O-])F

Synonyms

tert-butyl 2-[[3-benzyl-5-(2-fluoro-3-nitrophenyl)pyrazin-2-yl]amino]-3-(furan-2-yl)prop-2-enoate

IUPAC Name

4-[3-(hydroxymethyl)-5-[(E)-3-hydroxyprop-1-enyl]-7-methoxy-2,3-dihydro-1-benzofuran-2-yl]-2,6-dimethoxyphenol

Density

Solubility

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

Flash Point

Boiling Point

Melting Point

InChl

InChI=1S/C28H25FN4O5/c1-28(2,3)38-27(34)22(16-19-11-8-14-37-19)32-26-21(15-18-9-5-4-6-10-18)31-23(17-30-26)20-12-7-13-24(25(20)29)33(35)36/h4-14,16-17H,15H2,1-3H3,(H,30,32)

InChl Key

VISQIGRRFIEQDK-UHFFFAOYSA-N

WGK Germany

RID/ADR

HS Code Reference

2933990000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:500574-38-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

32075578

Abstract

Objectives
This study evaluated the incidence of colorectal cancer (CRC) according to the number of metabolic syndrome (MetS) components.

Methods
Using health checkup and insurance claims data of 6,365,409 subjects, the occurrence of CRC according to stage of MetS by sex was determined from the date of the health checkup in 2009 until December 31, 2018.

Results
Cumulative incidence rates (CIR) of CRC in men and women was 3.9 and 2.8 per 1000 (p < 0.001), respectively. CIR of CRC for the normal, pre-MetS, and MetS groups in men was 2.6, 3.9, and 5.5 per 1000 (p < 0.001) and CIR in women was 2.1, 2.9, and 4.5 per 1000 (p < 0.001), respectively. Compared with the normal group, the hazard ratio (HR) of CRC for the pre-MetS group was 1.25 (95% CI 1.17-1.33) in men and 1.09 (95% CI 1.02-1.17) in women, and the HR of CRC for the MetS group was 1.54 (95% CI 1.43-1.65) in men and 1.39 (95% CI 1.26-1.53) in women after adjustment. Conclusions We found that MetS is a risk factor for CRC in this study. Therefore, the prevention and active management of MetS would contribute to the prevention of CRC.

KEYWORDS

Metabolic syndrome, Colorectal cancer, Relevance, Koreans

Title

The relationship between metabolic syndrome and the incidence of colorectal cancer

Author

JungHyun Lee, Kun Sei Lee, Hyeongsu Kim, Hyoseon Jeong, Min-Jung Choi, Hai-Won Yoo, Tae-Hwa Han, Hyunjung Lee

Publish date

2020;


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