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Sipeimine

$225

  • Brand : BIOFRON

  • Catalogue Number : BF-S2028

  • Specification : 98%

  • CAS number : 61825-98-7

  • Formula : C27H43NO3

  • Molecular Weight : 429.63

  • PUBCHEM ID : 442977

  • Volume : 20mg

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Catalogue Number

BF-S2028

Analysis Method

HPLC,NMR,MS

Specification

98%

Storage

2-8°C

Molecular Weight

429.63

Appearance

White needle crystal

Botanical Source

Fritillaria pallidiflora

Structure Type

Alkaloids

Category

Standards;Natural Pytochemical;API

SMILES

CC1CCC2C(C3CCC4C(C3CN2C1)CC5C4CC(=O)C6C5(CCC(C6)O)C)(C)O

Synonyms

Raddeamine,Sipeimine/(3β,5α)-3,20-Dihydroxycevan-6-one/Imperialine/Cevan-6-one, 3,20-dihydroxy-, (3β,5α)-/Sipeimine/3β,20-Dihydroxy-5α-cevan-6-one/RADDEAMINE/Imperialin/Kashmirine/(3β,5α,17β)-3,20-Dihydroxycevan-6-one/3,20-dihydroxycevan-6-one/peiminine/Cevan-6-one, 3,20-dihydroxy-, (3β,5α,17β)-/Verticinone

IUPAC Name

(1R,2S,6S,9S,10S,11R,14S,15S,18S,20S,23R,24S)-10,20-dihydroxy-6,10,23-trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacosan-17-one

Density

1.2±0.1 g/cm3

Solubility

Methanol

Flash Point

296.8±30.1 °C

Boiling Point

567.1±50.0 °C at 760 mmHg

Melting Point

InChl

InChI=1S/C27H43NO3/c1-15-4-7-25-27(3,31)21-6-5-17-18(20(21)14-28(25)13-15)11-22-19(17)12-24(30)23-10-16(29)8-9-26(22,23)2/h15-23,25,29,31H,4-14H2,1-3H3/t15-,16-,17+,18+,19-,20-,21+,22-,23+,25-,26+,27-/m0/s1

InChl Key

IQDIERHFZVCNRZ-LRCDAWNTSA-N

WGK Germany

RID/ADR

HS Code Reference

2933990000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:61825-98-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

PMID

19227824

Abstract

Ten strains of endophytic fungi were isolated from the bulbs of the traditional Chinese medicinal plant Fritillaria ussuriensis. The extract from one of them, Fu7, showed a positive reaction with Dragendorff’s reagent and the same Rf value in thin-layer chromatography (TLC) analysis as authentic sipeimine. A further TLC scan and high-performance liquid chromatography-evaporative light-scattering detection (HPLC-ELSD) showed that one ingredient of the extract of strain Fu7 had a similar absorption curve in the range 200-700 nm and the same retention time as authentic sipeimine. Thus, the fungus produces the bioactive ingredient sipeimine, as does its host plant, and could be used for the production of sipeimine by fermentation.

Title

Sipeimine-producing endophytic fungus isolated from Fritillaria ussuriensis.

Author

Yin H1, Chen JL.

Publish date

2008 Nov-Dec

PMID

11173441

Title

Sipeimine, a steroidal alkaloid from Fritillaria roylei Hooker.

Author

Jiang RW1, Ma SS, But PP, Dong H, Mak TC.

Publish date

2001 Feb


Description :

Sipeimine is a natural product isolated from Fritillaria ussuriensis.IC50 value:Target:In vitro: Sipeimine can induce rejuvenation of a endophytic fungus; Sipeimine yield of the strain rejuvenated by adding 3% bulbus was effectively improved to 0.0563 mg/L and it is 21.9% higher than that of the initial strain [1].In vivo: