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Sodium Demethylcantharidate

$93

  • Brand : BIOFRON

  • Catalogue Number : BF-S2005

  • Specification : 98%

  • CAS number : 13114-29-9

  • Formula : C8H19O5.Na

  • Molecular Weight : 218.22

  • PUBCHEM ID : 8519

  • Volume : 20mg

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Catalogue Number

BF-S2005

Analysis Method

HPLC,NMR,MS

Specification

98%

Storage

2-8°C

Molecular Weight

218.22

Appearance

White powder

Botanical Source

synthesis

Structure Type

Others

Category

Standards;Natural Pytochemical;API

SMILES

C1CC2C(C(C1O2)C(=O)[O-])C(=O)[O-].[Na+].[Na+]

Synonyms

sodium 7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylate/disodium endothallate/disodium 1-oxabicyclo[2.2.1]heptane-2,3-dicarboxylate/disodium demethylcantharate/Na2(demethylcantharate)/Na2(DCA)

IUPAC Name

disodium;7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylate

Density

Solubility

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

Flash Point

Boiling Point

Melting Point

InChl

InChI=1S/C8H10O5.2Na/c9-7(10)5-3-1-2-4(13-3)6(5)8(11)12;;/h3-6H,1-2H2,(H,9,10)(H,11,12);;/q;2*+1/p-2

InChl Key

XRHVZWWRFMCBAZ-UHFFFAOYSA-L

WGK Germany

RID/ADR

HS Code Reference

2942000000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:13114-29-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

PMID

23861725

Abstract

Arteriovenous fistula (AVF) is an important vascular access for hemodialysis (HD) treatment but has 20-60% rate of early failure. Detecting association between patient’s parameters and early AVF failure is important for reducing its prevalence and relevant costs. Also predicting incidence of this complication in new patients is a beneficial controlling procedure. Patient safety and preservation of early AVF failure is the ultimate goal. Our research society is Hasheminejad Kidney Center (HKC) of Tehran, which is one of Iran’s largest renal hospitals. We analyzed data of 193 HD patients using supervised techniques of data mining approach. There were 137 male (70.98%) and 56 female (29.02%) patients introduced into this study. The average of age for all the patients was 53.87 ± 17.47 years. Twenty eight patients had smoked and the number of diabetic patients and nondiabetics was 87 and 106, respectively. A significant relationship was found between “diabetes mellitus,” “smoking,” and “hypertension” with early AVF failure in this study. We have found that these mentioned risk factors have important roles in outcome of vascular surgery, versus other parameters such as “age.” Then we predicted this complication in future AVF surgeries and evaluated our designed prediction methods with accuracy rates of 61.66%-75.13%.

Title

Implementation of Predictive Data Mining Techniques for Identifying Risk Factors of Early AVF Failure in Hemodialysis Patients

Author

Mohammad Rezapour, 1 Morteza Khavanin Zadeh, 2 ,* and Mohammad Mehdi Sepehri 1 , 3

Publish date

2013 Jun 4

PMID

17167100

Abstract

The adult human brain retains the capacity to generate new neurons in the hippocampal formation (Eriksson et al., 1998) and neuronal progenitor cells (NPCs) in the forebrain (Bernier et al., 2000), but to what extent it is capable of reacting to injuries, such as ischemia, is not known. We analyzed postmortem tissue from normal and pathological human brain tissue (n = 54) to study the cellular response to ischemic injury in the forebrain. We observed that cells expressing the NPC marker polysialylated neural adhesion cell molecule (PSA-NCAM) are continuously generated in the adult human subventricular zone (SVZ) and migrate along the olfactory tracts. These cells were not organized in migrating chains as in the adult rodent rostral migratory stream, and their number was lower in the olfactory tracts of brains from old (56-81 years of age) compared with young (29 + 36 years of age) individuals. Moreover, we show that in brains of patients of advanced age (60-87 years of age), ischemia led to an elevated number of Ki-67-positive cells in the ipsilateral SVZ without concomitant apoptotic cell death. Additionally, ischemia led to an increased number of PSA-NCAM-positive NPCs close to the lateral ventricular walls, compared with brains of comparable age without obvious neuropathologic changes. These results suggest that the adult human brain retains a capacity to respond to ischemic injuries and that this capacity is maintained even in old age.

KEYWORDS

ischemia, human, subventricular zone, neural progenitor cells, aging, neuropathology

Title

Increased Generation of Neuronal Progenitors after Ischemic Injury in the Aged Adult Human Forebrain

Author

Jadranka Macas, Christian Nern, Karl H. Plate, and Stefan Mommacorresponding author

Publish date

2006 Dec 13

PMID

31511634

Abstract

Estimating forces acting between our hand and objects is essential for dexterous motor control. An earlier study suggested that vision contributes to the estimation by demonstrating changes in grip force pattern caused by delayed visual feedback. However, two possible vision-based force estimation processes, one based on hand position and another based on object motion, were both able to explain the effect. Here, to test each process, we examined how visual feedback of hand and object each contribute to grip force control during moving an object (mass) connected to the grip by a damped-spring. Although force applied to the hand could be estimated from its displacement, we did not find any improvements by the hand feedback. In contrast, we found that visual feedback of object motion significantly improved the synchrony between grip and load forces. Furthermore, when both feedback sources were provided, the improvement was observed only when participants were instructed to direct their attention to the object. Our results suggest that visual feedback of object motion contributes to estimation of dynamic forces involved in our actions by means of inverse dynamics computation, i.e., the estimation of force from motion, and that visual attention directed towards the object facilitates this effect.

KEYWORDS

Computational neuroscience, Sensorimotor processing

Title

Better grip force control by attending to the controlled object: Evidence for direct force estimation from visual motion

Author

Shinya Takamukucorresponding author and Hiroaki Gomi

Publish date

2019 Sep 11


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