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Sodium ferulic


  • Brand : BIOFRON

  • Catalogue Number : BD-H0002

  • Specification : 98%

  • CAS number : 24276-84-4

  • Formula : C10H9NaO4

  • Molecular Weight : 216.17

  • PUBCHEM ID : 23669636

  • Volume : 20mg

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Catalogue Number


Analysis Method






Molecular Weight



White crystalline powder

Botanical Source

Ferula teterrima Kar. et Kir

Structure Type


Standards; Pharmaceutical/API Drug Impurities/Metabolites;




3-(4-Hydroxy-3-methoxyphenyl)-2-propenoic acid monosodium salt/Natrium-(2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoat/2-Propenoic acid,3-(4-hydroxy-3-methoxyphenyl)-,monosodium salt/Monosodium 3-(4-hydroxy-3-methoxyphenyl)-2-propenoate/Sodium (2E)-3-(4-hydroxy-3-methoxyphenyl)acrylate/(2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid, sodium salt/Sodium (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate/Sodium Ferulate/Monosodium 4-hydroxy-3-methoxycinnamate/Ferulic acid sodium salt/2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, monosodium salt/2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, sodium salt, (2E)- (1:1)/4-HYDROXY-3-METHOXYCINNAMIC ACID SODIUM SALT/Cinnamic acid,4-hydroxy-3-methoxy-,monosodium salt/Sodium 3-(4-hydroxy-3-methoxyphenyl)acrylate/Sodium 4-hydroxy-3-methoxycinnamate/Ferulic acid (sodium)





DMSO : 16.6 mg/mL (76.79 mM; Need ultrasonic and warming);

Flash Point


Boiling Point

372.3ºC at 760 mmHg

Melting Point



InChl Key


WGK Germany


HS Code Reference


Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:24276-84-4) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.




Liberating high value-added compounds ferulic acid (FA) and xylo-oligosaccharides (XOSs) from agricultural residues is a promising strategy for the utilization of lignocellulose. In this study, a bifunctional xylanase/feruloyl esterase from bacterial consortium EMSD5 was heterogeneously expressed in Escherichia coli. Depending on the inter-domain synergism of the recombinant enzyme rXyn10A/Fae1A, high yields of FA (2.78, 1.82, 1.15 and 7.31 mg/g substrate, respectively) were obtained from 20 mg in-soluble wheat arabinoxylan, de-starched wheat bran, ultrafine-grinding corn stover and steam-exploded corncob. Meanwhile, 3.210, 1.235, 1.215 and 0.823 mg xylose/XOSs were also released. For cost-saving enzyme production, we firstly constructed a recombinant E. coli, which could secrete the bifunctional xylanase/feruloyl esterase out of cells. When the recombinant E. coli was cultured in medium containing 200 mg de-starched wheat bran, 474 μg FA and 18.2 mg xylose/XOSs were also detected. Hence, rXyn10A/Fae1A and the recombinant strain showed great applied potential for FA and XOSs production.

Copyright © 2019 Elsevier Ltd. All rights reserved.


Agricultural residues; Bifunctional xylanase/feruloyl esterase; Extracellular secretion; Ferulic acid; Inter-domain synergism


Efficient ferulic acid and xylo-oligosaccharides production by a novel multi-modular bifunctional xylanase/feruloyl esterase using agricultural residues as substrates.


Wang R1, Yang J1, Jang JM2, Liu J1, Zhang Y1, Liu L1, Yuan H3.

Publish date

2020 Feb




Large amounts of tomato fruits and derived products are produced in China and may be contaminated by Alternaria mycotoxins, which may have the potential risks for human health. There is thus an increasing interest in reducing the mycotoxins. In the present study, 26 Alternaria strains isolated from tomato black rots were identified according to morphological and molecular grounds, and their mycotoxigenic abilities for alternariol (AOH), alternariol monomethyl-ether (AME) and tenuazonic acid (TeA) were also investigated. The results showed that A. alternate was the predominant species with incidence values of 65.4% (17/26), followed by A. brassicae (7/26) and A. tenuissima (2/26). A. alternate isolates showed the highest capacity for AOH, AME and TeA production among the studied isolates either in vitro or in vivo, suggested that A. alternata may be the most important mycotoxin-producing species in tomato fruits. Thus, UV-C irradiation was used to reduce the mycotoxin produced by A. alternata in our study. The results showed that low dose of UV-C irradiation (0.25 kJ/m2) could effectively inhibit mycotoxins production and penetration in tomatoes. Upon treatment with UV-C, there was 79.6, 76.4 and 51.4% of reduction in AOH, AME and TeA penetration when compared to untreated fruits. This may be associated with the enhanced phenolics by UV-C irradiation. In fact, the induced phenolics were including p-coumaric, ferulic and pyrocatechuic acids, of which p-coumaric acid (1.0 mM) displayed the highest reduction of TeA with 60.2%, whereas ferulic acid (1.0 mM) showed strong inhibitory effects on the AOH and AME production by 59.4 and 79.1%, respectively. Therefore, the application of UV-C irradiation seems to be a promising method for reducing the potential risk of Alternaria mycotoxins in fruits and also for enhancing phenolics of processing products.

Copyright © 2019 Elsevier B.V. All rights reserved.


Alternaria mycotoxin; Phenolics; Tomato fruits; UV-C irradiation


Effects of ultraviolet-c treatment on growth and mycotoxin production by Alternaria strains isolated from tomato fruits.


Jiang N1, Li Z2, Wang L1, Li H3, Zhu X4, Feng X1, Wang M5.

Publish date

2019 Dec 2




Ferulate (FA) units esterified to grass arabinoxylans are involved in cross-linking cell wall polymers. In this work, this contention is strengthened by the identification of FA homo- and heterodimers esterified to methyl arabinofuranoside (MeAra) units after their release from the xylan by mild acidolysis in dioxane/methanol/HCl. Acidolysis of poorly lignified maize bran cell walls provided diferulate (DFA) isomers, including those from 8-5, 8-O-4, and 5-5 interunit bonding, esterified to one or two MeAra units. Acidolysis of lignified grass samples released crossed dimers esterified to one MeAra unit and derived from the β-O-4 coupling of coniferyl alcohol to FA esters. The evaluation of these heterodimeric esters by LC-UV of their aglycones revealed that the parent structures occur in significant amounts in lignified cell walls (0.5-1 mg/g expressed as FA equivalents). The present results position mild acidolysis as an efficient strategy to obtain improved details regarding the FA-mediated cross-linking of grass cell walls.


cell wall cross-link; dehydrodimer; diferulate; lignification; monocot; radical coupling


Arabinose Conjugates Diagnostic of Ferulate-Ferulate and Ferulate-Monolignol Cross-Coupling Are Released by Mild Acidolysis of Grass Cell Walls.


Lapierre C1, Voxeur A1, Boutet S1, Ralph J2.

Publish date

2019 Nov 20

Description :

Ferulic acid (4-hydroxy-3-methoxycinnamic acid) is a phenolic compound present in several plants with claimed beneficial effects in prevention and treatment of disorders linked to oxidative stress and inflammation.IC50 value:Target: 5-HT ReceptorIn vitro: In the present study we have showed that pre-treatment with Ferulic Acid (FA) reduces NO accumulation in the culture medium of LPS-induced macrophage cells. Moreover, real-time experiments have revealed that FA has an inhibitory effect at the transcriptional level on the expression of some inflammatory mediators such as IL-6, TNF-α and iNOS and an activation effect on the expression of some antioxidant molecules such as Metallothioneins (MT-1, MT-2). Importantly, we have found that FA reduced the translocation of NF-E2-related factor 2 (Nrf2) and nuclear transcription factor-κB (NF-κB) into the nuclei through a reduction of the expression of phosphorylated IKK and consequently inhibited IL-6 and NF-κB promoter activity in a luciferase assay [1]. FA treatment significantly, although not completely, protected the cells against lead acetate-induced neurite outgrowth inhibition. The effects of FA could be blocked by PD98059, zinc protoporphyrin (Zn-PP), and Nrf2 shRNA. In addition, FA induced heme oxygenase 1 (HO-1) gene expression, enhanced antioxidant response element (ARE) promoter activity, promoted ERK1/2 phosphorylation, and Nrf2 translocation in PC12 cells exposed to lead acetate. ERK1/2 locate upstream of Nrf2 and regulate Nrf2-dependent HO-1 expression in antioxidative effects of FA [2].In vivo: We aimed to verify the possible antidepressant-like effect of acute oral administration of Ferulic acid produced an antidepressant-like effect in the FST and TST (0.01-10 mg/kg, p.o.), without ccompanying changes in ambulation. The pretreatment of mice with WAY100635 (0.1 mg/kg, s.c., a selective 5-HT1A receptor ntagonist) or ketanserin (5 mg/kg, i.p., a 5-HT2A receptor ntagonist) was able to reverse the anti-immobility effect of ferulicacid (0.01 mg/kg, p.o.) in the TST. The combination of fluoxetine (5 mg/kg, p.o.), paroxetine (0.1 mg/kg, p.o.) or sertraline (1 mg/kg, p.o.) with a sub-effective dose of ferulic acid (0.001 mg/kg, p.o.) produced a synergistic antidepressant-like effect in the TST, without causing hyperlocomotion in the open-field test. ferulic acid in the forced swimming test (FST) and tail suspension test (TST) in mice [3].