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Sparteine sulfate

$113

  • Brand : BIOFRON

  • Catalogue Number : BF-S2014

  • Specification : 98%

  • CAS number : 299-39-8

  • Formula : C15H28N2O4S

  • Molecular Weight : 332.459

  • PUBCHEM ID : 23616742

  • Volume : 20mg

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Catalogue Number

BF-S2014

Analysis Method

HPLC,NMR,MS

Specification

98%

Storage

2-8°C

Molecular Weight

332.459

Appearance

White powder

Botanical Source

herbs of Parochetus communis

Structure Type

Alkaloids

Category

Standards;Natural Pytochemical;API

SMILES

C1CCN2CC3CC(C2C1)CN4C3CCCC4.OS(=O)(=O)O

Synonyms

(7α,9α)-Sparteine sulfate (1:1)/Sparteinsulfat/(-)-Spartein,Sulfat/spartocin/Sparteine, sulfate/7,14-Methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine, dodecahydro-, (7R,7aR,14R,14aS)-, sulfate (1:1)/spareng/sparteine mono(hydrogen sulfate)/sparteal/(-)-sparteine,sulfate/(1S,2R,9S,10S)-7,15-Diazatetracyclo[7.7.1.0.0]heptadecansulfat/(1S,2R,9S,10S)-7,15-Diazatetracyclo[7.7.1.0.0]heptadecane sulfate/7,14-Methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine, dodecahydro-, (7S,7aR,14S,14aS)-, sulfate (1:1)/Sparteine sulfate (VAN)/[7S/sparm/Sparteine, sulfate (1:1)/spartin/spartein sulfate pentahydrate/Sparteine sulfate anhydrous/spatym/Spartea/spartepur/(1S,2R,9S,10S)-7,15-Diazatetracyclo[7.7.1.0.0]heptadecane sulfate/Sparteine Sulfate/spal/L-Spartein sulfat/Sparteine sulfate (1:1)

IUPAC Name

(1S,2R,9S,10S)-7,15-diazatetracyclo[7.7.1.02,7.010,15]heptadecane;sulfuric acid

Density

Solubility

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

Flash Point

148.3ºC

Boiling Point

340.9ºC at 760mmHg

Melting Point

135ºC

InChl

InChI=1S/C15H26N2.H2O4S/c1-3-7-16-11-13-9-12(14(16)5-1)10-17-8-4-2-6-15(13)17;1-5(2,3)4/h12-15H,1-11H2;(H2,1,2,3,4)/t12-,13-,14-,15+;/m0./s1

InChl Key

FCEHFCFHANDXMB-UMEYXWOPSA-N

WGK Germany

RID/ADR

HS Code Reference

2907290000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:299-39-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

PMID

3536704

Abstract

This study aimed at evaluating the influence of sparteine sulfate either upon basal plasma glucose and insulin or glucose-induced insulin secretion in normal man. Thirteen overnight fasted volunteers took part in this study; five of them were submitted to sparteine sulfate bolus (15 mg in 10 ml of saline solution) followed by a slow infusion (90 mg/100 ml X 60 min) and eight subjects underwent two different glucose pulses (20 gr. i.v.) in absence or in presence of sparteine, infused as described above. In basal conditions, along with sparteine infusion, plasma glucose showed a progressive and significant decrease (P less than 0.0001) and plasma insulin was significantly higher from min 10 to 120′ (P less than 0.0005-0.001). Even during the glucose-induced insulin secretion, in the presence of sparteine infusion, plasma glucose levels were significantly lower while plasma insulin levels were significantly higher when compared to those observed after glucose alone. The acute insulin response (AIR) was 42 +/- 10 microU/ml after glucose alone vs 67 +/- 9 microU/ml after glucose plus sparteine (P less than 0.05). Total insulinemic areas were significantly different being 1410 +/- 190 vs 2250 +/- 310 microU/ml/min (P less than 0.001) during glucose and glucose plus sparteine infusion, respectively. This study thereby, demonstrates that in normal man sparteine sulfate, administrated by intravenous infusion, is able to increase either basal or glucose-induced insulin secretion.

Title

Effect of sparteine sulfate on insulin secretion in normal men.

Author

Sgambato S, Passariello N, Paolisso G, Bisesti V, Tesauro P.

Publish date

1986 Oct


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