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Stearic acid

$43

  • Brand : BIOFRON

  • Catalogue Number : BF-S3024

  • Specification : 98%

  • CAS number : 57-11-4

  • Formula : C18H36O2

  • Molecular Weight : 284.484

  • Volume : 1000mg

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Catalogue Number

BF-S3024

Analysis Method

HPLC,NMR,MS

Specification

98%

Storage

2-8°C

Molecular Weight

284.484

Appearance

powder

Botanical Source

Trachycarpus fortunei

Structure Type

Others

Category

SMILES

CCCCCCCCCCCCCCCCCC(=O)O

Synonyms

IUPAC Name

Density

0.84

Solubility

DMSO : 125 mg/mL (439.40 mM; Need ultrasonic)
H2O : < 0.1 mg/mL (insoluble)

Flash Point

>230 °F

Boiling Point

361 °C(lit.)

Melting Point

67-72 °C(lit.)

InChl

InChI=1S/C18H36O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h2-17H2,1H3,(H,19,20)

InChl Key

QIQXTHQIDYTFRH-UHFFFAOYSA-N

WGK Germany

RID/ADR

HS Code Reference

2915700000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:57-11-4) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

PMID

31963838

Abstract

The hydrophobicity and anti-fouling properties of materials have important application value in industrial and agricultural production and people’s daily life. To study the relationship between the unit width L0 of the parabolic hydrophobic material and the hydrophobicity and anti-fouling properties, the rough surface structure of the parabolic with different widths was prepared by grinding with different SiC sandpapers, and further, to obtain hydrophobic materials through chemical oxidation and chemical etching, and modification with stearic acid (SA). The morphology, surface wetting and anti-fouling properties of the modified materials were characterized by SEM and contact angle measurement. The oil-water separation performance and self-cleaning performance of the materials were explored. The surface of the modified copper sheet forms a rough structure similar to a paraboloid. When ground with 1500 grit SiC sandpaper, it is more conducive to increase the hydrophobicity of the copper sheet surface and increase the contact angle of water droplets on the copper surface. Additionally, the self-cleaning and anti-fouling experiments showed that as L0 decreases, copper sheets were less able to stick to foreign things such as soil, and the better the self-cleaning and anti-fouling performance was. Based on the oil-water separation experiment of copper mesh, the lower L0 has a higher oil-water separation efficiency. The results showed that material with parabolic morphology has great self-cleaning, anti-fouling, and oil-water separation performance. The smaller the L0 was, the larger the contact angle and the better hydrophobic performance and self-cleaning performance were.

KEYWORDS

anti-fouling; contact angle; hydrophobicity; oil-water separation; parabolic.

Title

Hydrophobic and Anti-Fouling Performance of Surface on Parabolic Morphology

Author

Yu Li 1 2, Shengke Yang 1 2, Yangyang Chen 1 2, Dan Zhang 1 2

Publish date

2020 Jan 19

PMID

31819443

Abstract

Background: Ovarian cancer is a common malignancy in the female reproductive system with a high mortality rate. The most important reason is multidrug resistance (MDR) of cancer chemotherapy. To reduce side effects, reverse resistance and improve efficacy for the treatment of ovarian cancer, a “core-shell” polymeric nanoparticle-mediated curcumin and paclitaxel co-delivery platform was designed.

Methods: Nuclear magnetic resonance confirmed the successful grafting of polyethylenimine (PEI) and stearic acid (SA) (PEI-SA), which is designed as a mother core for transport carrier. Then, PEI-SA was modified with hyaluronic acid (HA) and physicochemical properties were examined. To understand the regulatory mechanism of resistance and measure the anti-tumor efficacy of the treatments, cytotoxicity assay, cellular uptake, P-glycoprotein (P-gp) expression and migration experiment of ovarian cancer cells were performed. In addition, adverse reactions of nanoformulation to the reproductive system were examined.

Results: HA-modified drug-loaded PEI-SA had a narrow size of about 189 nm in diameters, and the particle size was suitable for endocytosis. The nanocarrier could target specifically to CD44 receptor on the ovarian cancer cell membrane. Co-delivery of curcumin and paclitaxel by the nanocarriers exerts synergistic anti-ovarian cancer effects on chemosensitive human ovarian cancer cells (SKOV3) and multi-drug resistant variant (SKOV3-TR30) in vitro, and it also shows a good anti-tumor effect in ovarian tumor-bearing nude mice. The mechanism of reversing drug resistance may be that the nanoparticles inhibit the efflux of P-gp, inhibit the migration of tumor cells, and curcumin synergistically reverses the resistance of PTX to increase antitumor activity. It is worth noting that the treatment did not cause significant toxicity to the uterus and ovaries with the observation of macroscopic and microscopic.

Conclusion: This special structure of targeting nanoparticles co-delivery with the curcumin and paclitaxel can increase the anti-tumor efficacy without increasing the adverse reactions as a promising strategy for therapy ovarian cancer.

KEYWORDS

adverse reactions; co-delivery; curcumin; ovarian cancer; paclitaxel; reverse resistance.

Title

Co-Delivery of Curcumin and Paclitaxel by "Core-Shell" Targeting Amphiphilic Copolymer to Reverse Resistance in the Treatment of Ovarian Cancer

Author

Meng-Dan Zhao 1, Jun-Qin Li 2, Feng-Ying Chen 1, Wei Dong 3, Li-Juan Wen 4, Wei-Dong Fei 1, Xiao Zhang 1, Pei-Lei Yang 1, Xin-Mei Zhang 2, Cai-Hong Zheng 1

Publish date

2019 Dec 2

PMID

31783480

Abstract

TiO2 thin films with different titanium isopropoxide (TTIP):acetylacetone (AcacH) molar ratios in solution were prepared by the chemical spray pyrolysis method. The TTIP:AcacH molar ratio in spray solution varied from 1:3 to 1:20. TiO2 films were deposited onto the glass substrates at 350 °C and heat-treated at 500 °C. The morphology, structure, surface chemical composition, and photocatalytic activity of the obtained TiO2 films were investigated. TiO2 films showed a transparency of ca 80% in the visible spectral region and a band gap of ca 3.4 eV irrespective of the TTIP:AcacH molar ratio in the spray solution. TiO2 films consist of the anatase crystalline phase with a mean crystallite size in the range of 30-40 nm. Self-cleaning properties of the films were estimated using the stearic acid (SA) test. A thin layer of 8.8-mM SA solution was spin-coated onto the TiO2 film. The degradation rate of SA as a function of irradiation time was monitored by Fourier-transform infrared spectroscopy (FTIR). An increase in the TTIP:AcacH molar ratio from 1:4 to 1:8 resulted in a ten-fold increase in the photodegradation reaction rate constant (from 0.02 to the 0.2 min-1) under ultraviolet light and in a four-fold increase under visible light.

KEYWORDS

TiO2; acetylacetone; photocatalysis; stearic acid; thin film; ultrasonic spray pyrolysis.

Title

Effect of the Titanium Isopropoxide:Acetylacetone Molar Ratio on the Photocatalytic Activity of TiO 2 Thin Films

Author

Jekaterina Spiridonova 1, Atanas Katerski 1, Mati Danilson 2, Marina Krichevskaya 3, Malle Krunks 1, Ilona Oja Acik 1

Publish date

2019 Nov 27;


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