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Sterebins A

$538

  • Brand : BIOFRON

  • Catalogue Number : BD-P0428

  • Specification : 98.0%(HPLC)

  • CAS number : 107647-14-3

  • Formula : C18H30O4

  • Molecular Weight : 310.4284

  • PUBCHEM ID : 71694416

  • Volume : 5mg

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Quantity
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Catalogue Number

BD-P0428

Analysis Method

HPLC,NMR,MS

Specification

98.0%(HPLC)

Storage

2-8°C

Molecular Weight

310.4284

Appearance

Powder

Botanical Source

Structure Type

Diterpenoids

Category

SMILES

CC(=O)C=CC1C2(CCCC(C2C(C(C1(C)O)O)O)(C)C)C

Synonyms

(E)-4-[(1R,2S,3S,4R,8aS)-2,3,4-trihydroxy-2,5,5,8a-tetramethyl-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]but-3-en-2-one

IUPAC Name

(E)-4-[(1R,2S,3S,4R,8aS)-2,3,4-trihydroxy-2,5,5,8a-tetramethyl-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]but-3-en-2-one

Applications

Density

Solubility

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

Flash Point

Boiling Point

Melting Point

InChl

InChI=1S/C18H30O4/c1-11(19)7-8-12-17(4)10-6-9-16(2,3)14(17)13(20)15(21)18(12,5)22/h7-8,12-15,20-22H,6,9-10H2,1-5H3/b8-7+/t12-,13-,14?,15+,17-,18+/m1/s1

InChl Key

GUVJPXABQYFWPD-GSZDNMEJSA-N

WGK Germany

RID/ADR

HS Code Reference

2933990000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:107647-14-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

28932429

Abstract

The solvated title compound, bis­[2,6-bis­(1-{[4-(di­methyl­amino)­phen­yl]imino-κN}eth­yl)pyridine-κN]nickel(II) dichloride-di­chloro­methane-water (1/2/2), [Ni(C25H29N5)2]Cl2·2CH2Cl2·2H2O, represents a nickel(II) bis­(pyridine di­imine) complex with electron-donating di­methyl­amino­phenyl substituents. The complex crystallizes as a water/di­chloro­methane solvate with Z′ = 2, thus the asymmetric unit consists of two NiII complex cations, four chloride anions, four adventitious water and four di­chloro­methane solvent mol­ecules. Around each octa­hedrally coordinated NiII cation, one pendant phenyl group on each of the two ligands has an intra­molecular π-π inter­action with the pyridine ring of the other chelating ligand. In the crystal, pairs of water mol­ecules are hydrogen bonded to pairs of chlorine atoms. The di­chloro­methane solvent mol­ecules are likewise hydrogen bonded to the chloride anions.

KEYWORDS

crystal structure, nickel complex, pyridine di­imine, redox non-innocent ligand, electron-donating groups

Title

Synthesis and crystal structure of a disubstituted nickel(II) bis­[(di­methyl­amino­phenyl­imino)­eth­yl]pyridine chloride complex

Author

Morgan Matthews,a Madison Sendzik,a Adrienne Bruggeman,a Claire Kearns,a Allen G. Oliver,b and Dominic C. Babbinia,*

Publish date

2017 Jul 1;

PMID

30453968

Abstract

Background
Few countries in the Middle East have a population-based cancer registry, despite a clear need for accurate cancer statistics in this region. We therefore established a registry in the East Azerbaijan province, the sixth largest province in northwestern Iran.

Methods
We actively collected data from 20 counties, 62 cities, and 44 districts for the period between 20th March 2015 and 19th March 2016 (one Iranian solar year). The CanReg5 software was then used to estimate age-standardized incidence rates (ASRs) per 100,000 for all cancers and different cancer types.

Results
Data for 11,536 patients were identified, but we only analyzed data for 6655 cases after removing duplicates and non-residents. The ASR for all cancers, except non-melanoma skin cancer, was 167.1 per 100,000 males and 125.7 per 100,000 females. The most common cancers in men were stomach (ASR 29.7), colorectal (ASR 18.2), bladder (ASR 17.6), prostate (ASR 17.3), and lung (ASR 15.4) cancers; in women, they were breast (ASR 31.1), colorectal (ASR 13.7), stomach (13.3), thyroid (ASR 7.8), and esophageal (ASR 7.1) cancers. Both the death certificate rate (19.5%) and the microscopic verification rate (65%) indicated that the data for the cancer registry were of reasonable quality.

Conclusion
The results of the East Azerbaijan Population-based Cancer Registry show a high incidence of cancer in this province, especially gastrointestinal cancers.

KEYWORDS

Cancer, Registry, Population-based, Iran, Incidence

Title

Cancer incidence in the East Azerbaijan province of Iran in 2015-2016: results of a population-based cancer registry

Author

Mohammad Hossein Somi,1 Roya Dolatkhah,corresponding author2 Sepideh Sepahi,3 Mina Belalzadeh,3 Jabraeil Sharbafi,3 Leila Abdollahi,3 Azin Nahvijou,4 Saeed Nemati,4 Reza Malekzadeh,5 and Kazem Zendehdelcorresponding author4,6

Publish date

2018;

PMID

27193363

Abstract

Objective
Detecting cognitive decline in presymptomatic Alzheimer’s disease (AD) and early mild cognitive impairment (MCI) is challenging, but important for treatments targeting AD-related neurodegeneration. The current study aimed to investigate the utility and performance of internally developed robust norms and standard norms in identifying cognitive impairment in late middle-age (baseline age range = 36-68; M = 54).

Method
Robust norms were developed for neuropsychological measures based on longitudinally confirmed cognitively normal (CN) participants (n= 476). Seven hundred and seventy-nine participants enriched for AD risk were classified as psychometric MCI (pMCI) or CN based on standard and robust norms and “single-test” versus “multi-test” criteria.

Results
Prevalence of pMCI ranged from 3% to 49% depending on the classification scheme used. Those classified as pMCI using robust norms exhibited greater subjective cognitive complaints, diagnostic stability, and mild clinical symptoms at follow-up.

Conclusions
Results suggest that identifying early clinically relevant cognitive decline in late middle-age is feasible using robust norms and multi-test criteria.

KEYWORDS

Mild cognitive impairment, Alzheimer's disease, Norms/normative studies, Elderly/Geriatrics/Aging, Dementia, Learning and Memory

Title

Mild Cognitive Impairment in Late Middle Age in the Wisconsin Registry for Alzheimer's Prevention Study: Prevalence and Characteristics Using Robust and Standard Neuropsychological Normative Data

Author

Lindsay R. Clark,1,2 Rebecca L. Koscik,1 Christopher R. Nicholas,2,3 Ozioma C. Okonkwo,1,2,3 Corinne D. Engelman,1,4 Lisa C. Bratzke,1,5 Kirk J. Hogan,1,6 Kimberly D. Mueller,1 Barbara B. Bendlin,2,3 Cynthia M. Carlsson,1,2,3 Sanjay Asthana,1,2,3 Mark A. Sager,1 Bruce P. Hermann,1,7 and Sterling C. Johnson1,2,3,*

Publish date

2016 Nov;