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Succinic acid


  • Brand : BIOFRON

  • Catalogue Number : BF-S3013

  • Specification : 98%

  • CAS number : 110-15-6

  • Formula : C4H6O4

  • Molecular Weight : 118.09

  • PUBCHEM ID : 1110

  • Volume : 100mg

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Catalogue Number


Analysis Method






Molecular Weight



White crystal

Botanical Source

Angelica sinensis

Structure Type



Standards;Natural Pytochemical;API




4-02-00-01908/Butane diacid/Butanedioic acid,natural/HOOC-CH2-CH2-COOH/4-02-00-01908 (Beilstein Handbook Reference)/Bernsteinsaure [German]/Succinic acid/1,4-Butanedioic acid/1,2-Ethanedicarboxylic acid/Sal succini/QV2VQ/Succinic acid/Butanedioic acid/Asuccin/Katasuccin/Wormwood/spirit of amber/AMBER ACID


butanedioic acid


1.4±0.1 g/cm3


Methanol; DMSO

Flash Point

110.9±16.3 °C

Boiling Point

236.1±13.0 °C at 760 mmHg

Melting Point

185 °C


InChl Key

WGK Germany


HS Code Reference


Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:110-15-6) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate




Environmental conditions, particularly pH, have significant effects on the efficiency and final titers of bio-based products. Therefore, these factors need to be identified to ensure the fermentation process is economically attractive. In this study, strategies for controlling pH were optimized to enhance succinic acid production by Corynebacterium crenatum J-2. The results indicate that pH 6.8 is the optimal value for anaerobic succinic acid production by C. crenatum J-2 in terms of productivity and titer. The use of Mg(OH)2 as the neutralizing agent for pH control resulted in the highest levels of succinic acid concentration, yield, and productivity; superior to the levels obtained with Ca(OH)2, KOH, and NaOH. Under conditions of pH 6.8 and Mg(OH)2 as the neutralizing agent, 45.7 g/L succinic acid was produced within 12 h during the prophase of anaerobic fermentation, resulting in a succinic acid productivity of 3.8 g/(L·h). Succinic acid concentration reached 53.8 g/L at 22 h, with a productivity of 2.45 g/(L·h). The results of this study will be useful for the development of highly efficient succinic acid production processes utilizing industrial Corynebacterium spp. strains.


Anaerobic fermentation; Corynebacterium crenatum; Neutralizing agent optimization; Succinic acid; pH control.


Influence of pH and Neutralizing Agent on Anaerobic Succinic Acid Production by a Corynebacterium Crenatum Strain


Xiaoju Chen 1 , Xuefeng Wu 2 , Shaotong Jiang 3 , Xingjiang Li 3

Publish date

2017 Oct




In this study, six different herbal-extraction residues were evaluated for succinic acid production in terms of chemical composition before and after dilute acid pretreatment (DAP) and sugar release performance. Chemical composition showed that pretreated residues of Glycyrrhiza uralensis Fisch (GUR) and Morus alba L. (MAR) had the highest cellulose content, 50% and 52%, respectively. Higher concentrations of free sugars (71.6 g/L total sugar) and higher hydrolysis yield (92%) were both obtained under 40 FPU/g DM at 10% solid loading for GUR. Using scanning electron microscopy (SEM), GUR was found to show a less compact structure due to process of extraction. Specifically, the fibers in pretreated GUR were coarse and disordered compared with that of GUR indicated by SEM. Finally, 65 g/L succinic acid was produced with a higher yield of 0.89 g/g total sugar or 0.49 g/g GUR. Our results illustrate the potential of GUR for succinic acid production.


Biomass; Herbal-extraction residues; Succinic acid.


Efficient Production of Succinic Acid From Herbal Extraction Residue Hydrolysate


Caixia Wang 1 , Xinyao Su 2 , Wei Sun 1 , Sijing Zhou 3 , Junyu Zheng 1 , Mengting Zhang 4 , Mengchu Sun 5 , Jianping Xue 5 , Xia Liu 6 , Jianmin Xing 7 , Shilin Chen 8

Publish date

2018 Oct




Succinic acid (SA) has been recognized as one of the most important bio-based building block chemicals due to its numerous potential applications. Fermentation SA production from renewable carbohydrate feedstocks can have the economic and sustainability potential to replace petroleum-based production in the future, not only for existing markets, but also for new larger volume markets. Design and operation of bio-reactors play a key role. During the last 20 years, many different fermentation strategies for SA production have been described in literature, including utilization of immobilized biocatalysts, integrated fermentation and separation systems and batch, fed-batch, and continuous operation modes. This review is an overview of different fermentation process design developed over the past decade and provides a perspective on remaining challenges for an economically feasible succinate production processes. The analysis stresses the idea of improving the efficiency of the fermentation stage by improving bioreactor design and by increasing bioreactor performance.


Succinic acid; batch and continuous process; bioreactor; biorefinery; fermentation.


Bioreactors for Succinic Acid Production Processes


Mariateresa Ferone 1 2 , Francesca Raganati 1 , Giuseppe Olivieri 1 3 , Antonio Marzocchella 1

Publish date

2019 Jun

Description :

Succinic acid is an intermediate product of the tricarboxylic acid cycle, as well as one of fermentation products of anaerobic metabolism.