This product is isolated and purified from the herbs of Lonicera maackii
Drugs & Clinic ,2014, 29 (5) :459-464. Chemical constituents of Dipsaci Radix.[Reference: WebLink]To study the chemical constituents of Dipsaci Radix. Methods The compounds were isolated by macroporous resin, reverse phase C18 silica gel, and semi-prepative HPLC. Their structures were identified on the basis of physicochemical properties and spectroscopic data. Results Thirteen compounds were separated, seven of which were iridoid glycosides, and six of which were lignans, identified as loganin(1), sweroside(2), 6'-O-beta-D-Apiofuranosylsweroside(3), dipsanoside H(4), dipsanoside F(5), dipsanoside E(6), triplostoside A(7),(7R, 8S, 7'R, 8'S)-5-methoxyprinsepiol-4-O-β-D-glucopyranoside(8),(7R, 8S, 7'R, 8'S)-prinsepiol-4-O-β-D-glucopyranoside(9), acanthoside D(10),(7R, 8S, 7'R, 8'S)-fraxiresinol-4'-O-β-D-glucopyranoside(11),(7R, 8S, 7'R, 8'S)-8-hydroxypinoresinol-4'-O-β-D-glucopyranoside(12), and(7R, 8S, 7'R, 8'S)-8-hydroxypinoresinol-4-O-β-Dglucopyranoside(13), respectively. Conclusion Compounds 8, 9, and 11—13 are isolated from this genus for the first time.
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
800.2±65.0 °C at 760 mmHg
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provides coniferyl ferulate(CAS#:266678-59-5) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate
Little is known about the relationship between sleep and obesity in young adults, particularly college students. This study examined the relationship between sleep (i.e., sleep duration and quality) and obesity in a large and diverse binational sample of college students.
Analyses were based on a 40-item paper survey from 2016/2017 to 2017/2018 academic years, with a 72% response rate. The samples were 1578 college students aged 18-25 years from five universities (two in the U.S. and three in South Korea). Weight and height were measured objectively; other measures (e.g., health behaviors) were self-reported. Multinomial logistic regression was used to assess the association between sleep duration and independent variables (race/nationality, gender, and BMI). Poisson regression was used to examine the relationship between sleep quality and independent variables.
Overall, blacks had a higher adjusted odds ratio (AOR) of short sleep (< 7 h/night) than whites (AOR = 1.74, P < .01); overweight participants had a higher AOR of short sleep than normal weight participants (AOR = 1.52, P < .01); and obese participants had a higher AORs of both short and long sleep (> 9 h/night) (AOR = 1.67, P < .01; AOR = 1.79, P < .05, respectively). Among men, being black, overweight, and obesity were associated with short sleep (P < .05), whereas only obesity was related to short sleep among women (P < .05). In analyses stratified by race and nationality, overweight and obesity were related to short sleep among blacks only (P < .05). Overall, sleep quality (getting enough sleep to feel rested in the morning in the past 7 days) was worse in blacks and South Koreans than whites (P < .05), worse in women than men (P < .05), and worse in participants with obesity than normal weight participants (P < .05). Conclusions Obesity was associated with both short (< 7 h/night) and long sleep duration (> 9 h/night) and poor sleep quality among all participants. In comparison with whites, blacks were more like to have short sleep, and blacks and South Koreans had worse sleep quality. Further investigations using a larger sample of college students in multiple countries may be helpful to identify target populations who are at a greater risk of obesity and sleep problems.
Sleep, Obesity, Race, South Korea, Gender
Relationship between sleep and obesity among U.S. and South Korean college students
Jaesin Sa,1 Siyoung Choe,2 Beom-young Cho,3 Jean-Philippe Chaput,4 Gyurin Kim,5 Chae-Hee Park,6 Joon Chung,7 Yoojin Choi,8 Beatrice Nelson,9 and Yongkyu Kimcorresponding author10
A chemical cross-talk between plants and insects is required in order to achieve a successful co-adaptation. In response to herbivory, plants produce specific compounds, and feeding insects respond adequately7 to molecules produced by plants. Here we show the role of the gut microbial community of the mint beetle Chrysolina herbacea in the chemical cross-talk with Mentha aquatica (or watermint).
By using two-dimensional gas chromatography-mass spectrometry we first evaluated the chemical patterns of both M. aquatica leaf and frass volatiles extracted by C. herbacea males and females feeding on plants, and observed marked differences between males and females volatiles. The sex-specific chemical pattern of the frass paralleled with sex-specific distribution of cultivable gut bacteria. Indeed, all isolated gut bacteria from females belonged to either α- or γ-Proteobacteria, whilst those from males were γ-Proteobacteria or Firmicutes. We then demonstrated that five Serratia marcescens strains from females possessed antibacterial activity against bacteria from males belonging to Firmicutes suggesting competition by production of antimicrobial compounds. By in vitro experiments, we lastly showed that the microbial communities from the two sexes were associated to specific metabolic patterns with respect to their ability to biotransform M. aquatica terpenoids, and metabolize them into an array of compounds with possible pheromone activity.
Our data suggest that cultivable gut bacteria of Chrysolina herbacea males and females influence the volatile blend of herbivory induced Mentha aquatica volatiles in a sex-specific way.
Electronic supplementary material
The online version of this article (doi:10.1186/s12870-017-0986-6) contains supplementary material, which is available to authorized users.
Mentha aquatica, Chrysolina herbacea, Terpenoids, Insect pheromones, Gut microbial community, Microbial organic volatile compounds, Antimicrobial compounds
Cultivable gut bacteria provide a pathway for adaptation of Chrysolina herbacea to Mentha aquatica volatiles
Graziano Pizzolante,#1 Chiara Cordero,#2 Salvatore M. Tredici,1 Davide Vergara,1 Paola Pontieri,3 Luigi Del Giudice,3 Andrea Capuzzo,4 Patrizia Rubiolo,2 Chidananda N. Kanchiswamy,5 Simon A. Zebelo,6 Carlo Bicchi,2 Massimo E. Maffei,corresponding author4 and Pietro Alifanocorresponding author1
Testing for hepatitis C virus (HCV) infection may reduce the risk of liver-related morbidity, by facilitating earlier access to treatment and care. This review investigated the effectiveness of targeted testing interventions on HCV case detection, treatment uptake, and prevention of liver-related morbidity. A literature search identified studies published up to 2013 that compared a targeted HCV testing intervention (targeting individuals or groups at increased risk of HCV) with no targeted intervention, and results were synthesised using meta-analysis. Exposure to a targeted testing intervention, compared to no targeted intervention, was associated with increased cases detected [number of studies (n) = 14; pooled relative risk (RR) 1.7, 95 % CI 1.3, 2.2] and patients commencing therapy (n = 4; RR 3.3, 95 % CI 1.1, 10.0). Practitioner-based interventions increased test uptake and cases detected (n = 12; RR 3.5, 95 % CI 2.5, 4.8; and n = 10; RR 2.2, 95 % CI 1.4, 3.5, respectively), whereas media/information-based interventions were less effective (n = 4; RR 1.5, 95 % CI 0.7, 3.0; and n = 4; RR 1.3, 95 % CI 1.0, 1.6, respectively). This meta-analysis provides for the first time a quantitative assessment of targeted HCV testing interventions, demonstrating that these strategies were effective in diagnosing cases and increasing treatment uptake. Strategies involving practitioner-based interventions yielded the most favourable outcomes. It is recommended that testing should be targeted at and offered to individuals who are part of a population with high HCV prevalence, or who have a history of HCV risk behaviour.
Electronic supplementary material
The online version of this article (doi:10.1007/s10654-014-9958-4) contains supplementary material, which is available to authorized users.
Hepatitis C, Testing, Systematic review, Meta-analysis
Targeted hepatitis C antibody testing interventions: a systematic review and meta-analysis
Esther Jane Aspinall,corresponding author Joseph Samuel Doyle, Stephen Corson, Margaret Elena Hellard, David Hunt, David Goldberg, Tim Nguyen, Yngve Falck-Ytter, Rebecca Lynn Morgan, Bryce Smith, Mark Stoove, Stefan Zbyszko Wiktor, and Sharon Hutchinson