Taurine/tauphon/Taukard/taurine zwitterion/2-aminoethanesulphonic acid/b-Aminoethylsulfonic acid/Ethanesulfonic acid, 2-amino-/2-aminoethane sulfonic acid/TATU/TURIN/2-aminoethylsulfonic acid/2-sulfoethylamine/β-Aminoethylsulfonic acid/O-Due/Taufon/2-Aminoethanesulfonic acid
Taurine is an organic acid widely distributed in animal tissues.Target: OthersTaurine is a major constituent of bile and can be found in the large intestine and accounts for approximately 0.1% of total human body weight . Taurine is present in high concentration in algae and in the animals including insects and arthropods, but is generally absent or present in traces in the bacterial and plant kingdoms . In cardiac tissue alone, taurine levels of 20 mM or higher may be found. Taurine availability protects against cholestasis induced by monohydroxy bile acids remains confined to guinea pigs . Oral supplementation of taurine results in increased plasma taurine concentrations and is associated with normalization of left ventricular function in both groups of cats. Myocardial concentrations of taurine are directly related to plasma concentrations and low plasma concentrations are found to be associated with myocardial failure in cats, proposing a direct link occurs between decreased taurine concentration in the myocardium and decreased myocardial mechanical function .
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provides coniferyl ferulate(CAS#:107-35-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate
Taurine or 2-aminoethanesulfonic has many fundamental biological roles such as conjugation of bile acids, antioxidation, osmoregulation, membrane stabilization, and modulation of calcium signaling. It is essential for cardiovascular function and development and function of the skeletal muscle, the retina, and the central nervous system. Functions of taurine include osmoregulation; membrane stabilization; modulation of calcium levels; and antioxidation, antiapoptotic, anti-inflammatory, and antilipid activities. Taurine was first discovered as a component of ox (Bos taurus, from which its name is derived) bile in 1827; it had taken over a century before insights into its physiological functions were made. The present review throws light on the multifactorial properties of taurine and its potential to be used in periodontal therapy.
Anti-inflammatory; antilipid action; antioxidant; periodontitis; taurine
Taurine: A Potential Mediator for Periodontal Therapy
Swantika Chaudhry 1 , Bhuvanesh Tandon 2 , Akanksha Gupta 3 , Sugandha Gupta 4
Taurine is the most abundant amino acid in the retina. In the 1970s, it was thought to be involved in retinal diseases with photoreceptor degeneration, because cats on a taurine-free diet presented photoreceptor loss. However, with the exception of its introduction into baby milk and parenteral nutrition, taurine has not yet been incorporated into any commercial treatment with the aim of slowing photoreceptor degeneration. Our recent discovery that taurine depletion is involved in the retinal toxicity of the antiepileptic drug vigabatrin has returned taurine to the limelight in the field of neuroprotection. However, although the retinal toxicity of vigabatrin principally involves a deleterious effect on photoreceptors, retinal ganglion cells (RGCs) are also affected. These findings led us to investigate the possible role of taurine depletion in retinal diseases with RGC degeneration, such as glaucoma and diabetic retinopathy. The major antioxidant properties of taurine may influence disease processes. In addition, the efficacy of taurine is dependent on its uptake into retinal cells, microvascular endothelial cells and the retinal pigment epithelium. Disturbances of retinal vascular perfusion in these retinal diseases may therefore affect the retinal uptake of taurine, resulting in local depletion. The low plasma taurine concentrations observed in diabetic patients may further enhance such local decreases in taurine concentration. We here review the evidence for a role of taurine in retinal ganglion cell survival and studies suggesting that this compound may be involved in the pathophysiology of glaucoma or diabetic retinopathy. Along with other antioxidant molecules, taurine should therefore be seriously reconsidered as a potential treatment for such retinal diseases.
Diabetic retinopathy; Glaucoma; Neuroprotection; Nutrition; Retinal degeneration; Retinal ganglion cells; Retinitis pigmentosa; Taurine; Taurine transporter.
Taurine: The Comeback of a Neutraceutical in the Prevention of Retinal Degenerations
Nicolas Froger 1 , Larissa Moutsimilli 2 , Lucia Cadetti 2 , Firas Jammoul 2 , Qing-Ping Wang 2 , Yichao Fan 2 , David Gaucher 3 , Serge G Rosolen 2 , Nathalie Neveux 4 , Luc Cynober 4 , Jose-Alain Sahel 5 , Serge Picaud 6
Taurine is a ubiquitous dietary constituent of most mammals and is present in especially high concentrations in the tissues of developing mammals. Research to date indicates that taurine plays an important role in the development of the nervous system and the process of migration in particular. It is speculated that taurine uptake and release, in conjunction with glutamate uptake and release, may represent one form of communication between neurons and glial cells. The need of taurine by the body is emphasized by the ability of the kidney to curtail taurine excretion to conserve taurine in the face of a low dietary taurine intake. The evidence for a special role of taurine in development is considered and discussed.
Taurine in Development
J A Sturman 1