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Thunberginol C

$1,152

  • Brand : BIOFRON

  • Catalogue Number : BN-O1635

  • Specification : 98%(HPLC)

  • CAS number : 147517-06-4

  • Formula : C15H12O5 

  • Molecular Weight : 272.3

  • PUBCHEM ID : 10333412

  • Volume : 5mg

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Catalogue Number

BN-O1635

Analysis Method

Specification

98%(HPLC)

Storage

-20℃

Molecular Weight

272.3

Appearance

Powder

Botanical Source

This product is isolated and purified from the rhizomes of Saussurea superba

Structure Type

Category

SMILES

C1C(OC(=O)C2=C1C=C(C=C2O)O)C3=CC=C(C=C3)O

Synonyms

6,8-Dihydroxy-3-(4-hydroxyphenyl)-3,4-dihydro-1H-isochromen-1-one/1H-2-Benzopyran-1-one, 3,4-dihydro-6,8-dihydroxy-3-(4-hydroxyphenyl)-/thunberginol c

IUPAC Name

Density

1.5±0.1 g/cm3

Solubility

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

Flash Point

232.0±23.6 °C

Boiling Point

595.8±50.0 °C at 760 mmHg

Melting Point

InChl

InChl Key

WMAITHDYVBQITD-UHFFFAOYSA-N

WGK Germany

RID/ADR

HS Code Reference

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:147517-06-4) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

8795265

Abstract

Following the characterization of thunberginols A, B, and F, six bioactive principles, thunberginols C, D, and E, thunberginol G 3′-O-glucoside, (-)-hydrangenol 4′-O-glucoside, and (+)-hydrangenol 4′-O-glucoside, were isolated from Hydrangeae Dulcis Folium, the processed leaves of Hydrangea macrophylla SERINGE var. thunbergii MAKINO, together with four kaempferol and quercetin oligoglycosides. Their chemical structures have been determined on the basis of chemical and physicochemical evidence. Thunberginols C, D, E, and G and (-)-hydrangenol 4′-O-glucoside showed antiallergic activity in the in vitro bioassay using the Schultz-Dale reaction. These components also exhibited inhibitory activities on the histamine release from rat mast cells and on the histamine-induced contraction in isolated guinea pig tracheal chain. In addition, thunberginols C, D, E, and G showed antimicrobial activities against oral bacteria.

Title

Development of bioactive functions in hydrangeae dulcis folium. V. On the antiallergic and antimicrobial principles of hydrangeae dulcis folium. (2). Thunberginols C, D, and E, thunberginol G 3'-O-glucoside, (-)-hydrangenol 4'-o-glucoside, and (+)-hydrangenol 4'-O-glucoside.

Author

Yoshikawa M1, Matsuda H, Shimoda H, Shimada H, Harada E, Naitoh Y, Miki A, Yamahara J, Murakami N.

Publish date

1996 Aug

PMID

1363465

Abstract

New antiallergic and antimicrobial dihydroisocoumarins, thunberginols C, D, and E, were isolated from Hydrangeae Dulcis Folium, the fermented and dried leaves of Hydrangea macrophylla SERINGE var. thunbergii MAKINO, together with new dihydroisocoumarin glycosides, thunberginol G 3′-O-glucoside and (-)-hydrangenol 4′-O-glucoside. Their chemical structures have been determined on the basis of chemical and physicochemical evidence. Thunberginols C, D, E, G, and (-)-hydrangenol 4′-O-glucoside showed antiallergic activity in the in vitro bioassay using the Schults-Dale reaction in sensitized guinea pig bronchial muscle, and they also exhibited antimicrobial activity against oral bacteria.

Title

Thunberginols C, D, and E, new antiallergic and antimicrobial dihydroisocoumarins, and thunberginol G 3'-O-glucoside and (-)-hydrangenol 4'-O-glucoside, new dihydroisocoumarin glycosides, from Hydrangeae Dulcis Folium.

Author

Yoshikawa M1, Uchida E, Chatani N, Kobayashi H, Naitoh Y, Okuno Y, Matsuda H, Yamahara J, Murakami N.

Publish date

1992 Dec


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