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provides coniferyl ferulate(CAS#:85329-59-5) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate
Rabdosia trichocarpa is used in a popular home-made remedy for gastric and stomachic complaints in Japan. A diterpene, trichorabdal A from R. trichocarpa, showed a very strong in vitro antibacterial activity against Helicobacter pylori. With regard to the antibacterial activity of the extract and constituents of R. trichocarpa against H. pylori, the effect of traditional use of this plant for the treatment of gastritis is probably due to the suppression of H. pylori since the extract of R. trichocarpa particularly inhibits the growth of H. pylori. It could be a promising native herb treatment for patients with gastric complaints including gastric ulcer caused by H. pylori.
Antibacterial Activity of Trichorabdal A From Rabdosia Trichocarpa Against Helicobacter Pylori
S Kadota 1, P Basnet, E Ishii, T Tamura, T Namba
The first total syntheses of (-)-trichorabdal A and (-)-longikaurin E are reported. A unified synthetic strategy is employed that relies on a Pd-mediated oxidative cyclization of a silyl ketene acetal to generate an all-carbon quaternary center and build the bicyclo[3.2.1]octane framework. These studies, taken together with our previous synthesis of (-)-maoecrystal Z, demonstrate that three architecturally distinct ent-kauranoids can be prepared from a common spirolactone intermediate.
A Unified Strategy to Ent-Kauranoid Natural Products: Total Syntheses of (-)-Trichorabdal A and (-)-Longikaurin E
John T S Yeoman 1, Victor W Mak, Sarah E Reisman
2013 Aug 14
Four antibacterial diterpenes, trichorabdals A, B, C and H were isolated from the leaves of Rabdosia trichocarpa and the relationship between their conformations analysed by spectroscopic and computational methods. Their antibacterial activity is discussed.
Antibacterial Trichorabdal Diterpenes From Rabdosia Trichocarpa
K Osawa 1, H Yasuda, T Maruyama, H Morita, K Takeya, H Itokawa