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Tricin

$1,143

  • Brand : BIOFRON

  • Catalogue Number : BD-P0404

  • Specification : 98.0%(HPLC)

  • CAS number : 520-32-1

  • Formula : C17H14O7

  • Molecular Weight : 330.3

  • PUBCHEM ID : 5281702

  • Volume : 25mg

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Catalogue Number

BD-P0404

Analysis Method

Specification

98.0%(HPLC)

Storage

-20℃

Molecular Weight

330.3

Appearance

Yellow powder

Botanical Source

This product is isolated and purified from the herb of Avena sativa

Structure Type

Category

SMILES

COC1=CC(=CC(=C1O)OC)C2=CC(=O)C3=C(C=C(C=C3O2)O)O

Synonyms

Tricetin 3',5'-di-methyl ether/5,7-Dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-4H-1-benzopyran-4-one/3',5'-DIMETHOXY-4',5,7-TRIHYDROXYFLAVONE/5,7,4'-trihydroxy-3',5'-dimethoxyflavone/Tricin/4',5,7-trihydroxy-3',5'-dimethoxyflavone/3',5'-O-dimethyltricetin/4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-/5,7-dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)chromen-4-one/3',5'-di-O-methyltricetin/5,7-Dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-4H-chromen-4-one/tricetine-3',5'-dimethyl ether

IUPAC Name

Applications

Density

1.5±0.1 g/cm3

Solubility

Methanol

Flash Point

224.0±23.6 °C

Boiling Point

598.5±50.0 °C at 760 mmHg

Melting Point

InChl

InChl Key

HRGUSFBJBOKSML-UHFFFAOYSA-N

WGK Germany

RID/ADR

HS Code Reference

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:520-32-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

30526376

Abstract

This study was undertaken to determine the effects of enzyme-treated Zizania latifolia (ETZL) and of its major compound tricin on skin photo-aging and to investigate the mechanisms involved. It was found ETZL and tricin suppressed matrix metalloproteinase (MMP) production and increased type I-procollagen production in UVB-irradiated human dermal fibroblasts (HDFs). Furthermore, ETZL and tricin significantly up-regulated the expressions of the antioxidant enzymes HO-1 and SOD1, reduced UVB-induced reactive oxygen species (ROS) generation and mitogen-activated protein kinase (MAPK) induction by ROS and thereby attenuated activator protein-1 (AP-1) expression. In addition, ETZL and tricin both reduced the phosphorylations of IκBα and IKKα/ß and κB blocked the nuclear translocation of nuclear factor-κB (NF-κB) p65. These results show that ETZL have skin protective effects against UVB and suggest tricin as major efficacious material in ETZL protecting skin photoaging.

KEYWORDS

MAPK/AP-1; MMPs; NF-κB; tricin

Title

Protection against UVB-induced damages in human dermal fibroblasts: efficacy of tricin isolated from enzyme-treated Zizania latifolia extract.

Author

Park SH1,2, Lee SS3, Bang MH3, Jo SK4, Jhee KH2, Yang SA5.

Publish date

2019 Mar

PMID

30360380

Abstract

Xanthine oxidase, an enzyme present in significant levels in the intestine and liver, metabolizes hypoxanthine to xanthine and xanthine to uric acid in the purine catabolic pathway. An inhibitory compound acting against xanthine oxidase was isolated from sweet white clover (Melilotus albus) by bioassay and high-performance liquid chromatography guided separation. It was identified as tricin by spectroscopic analysis. Tricin possessed a potent xanthine oxidase inhibitory activity with an IC50 value of 4.13 μM. Further inhibition kinetics data indicated it to be a mixed-type inhibitor and Ki and KI values were determined to be 0.47 μM and 4.41 μM. To find a rich source of tricin, the distribution of tricin in seven different tissues from four Gramineae species was investigated by high-performance liquid chromatography analysis. The highest amount (1925.05 mg/kg dry materials) was found in the straw of wheat, which is considered as a potentially valuable source of natural tricin.

KEYWORDS

Gramineae species; Melilotus albus Medic. ex Desr; tricin; xanthine oxidase

Title

Isolation of Tricin as a Xanthine Oxidase Inhibitor from Sweet White Clover (Melilotus albus) and Its Distribution in Selected Gramineae Species.

Author

Liu XX1, Sun SW2, Yuan WJ3, Gao H4, Si YY5, Liu K6, Zhang S7, Liu Y8, Wang W9.

Publish date

2018 Oct 22;

PMID

30292367

Abstract

Lippia alba is a popular Brazilian herb known as ‘cidreira’ that presents several chemotypes which exhibit different chemical profile and they are widely used as seasonings and traditional medicine. This work describes the seasonal variation of metabolites of polar extracts of carvone and linalool chemotypes, identified by GC-MS analyses of the essential oils. A methodology was elaborated in order to obtain a seasonal variation in the chemical composition of leaf employing HPLC-DAD. Acteoside, isoacteoside, geneposidic acid, 8-epi-loganin, mussaenoside, luteolin 7-O-glucoside, apigenin 7-O-glucuronide and tricin 7-O-diglucuronide have been isolated and identified for validation procedures and chromatographic analysis. Geneposidic acid was presented in all samples, in contrast to the 8-epi-loganin and, mussaenoside which were presented only in the carvone-chemotype. Acteoside was the major metabolite detected from July to November while tricin-7-O-diglucuronide was the major compound in all other months. Besides, phenylpropanoids are predominant in winter and flavonoids in summer season.

Copyright © 2017 Elsevier Ltd. All rights reserved.

KEYWORDS

8-epi-Loganin (PubChem CID:100955855); Acteoside (PubChem CID: 5281800); Apigenin 7-O- glucuronide (PubChem CID: 24721579); Chemotypes; Geneposidic acid (PubChem CID: 443354); Iridoids; Isoacteoside (PubChem CID: 6476333); Lippia alba; Luteolin 7-O-glucuronide (PubChem CID 528060); Mussaenoside (PubChem CID: 182423); Seasonal chemical variation; Tricin 7-O-glucoronide (PubChem CID 44258271)

Title

Seasonal variation in the chemical composition of two chemotypes of Lippia alba.

Author

Gomes AF1, Almeida MP2, Leite MF3, Schwaiger S4, Stuppner H4, Halabalaki M5, Amaral JG2, David JM6.

Publish date

2019 Feb 1;